The Harvard Gazette

Diabetes

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Fried foods tied to diabetes and heart disease

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DateJuly 30, 2014

Searching for “broken genes” — those whose protective effects come from shutting off and ceasing to function — gives drug companies an important leg up, explained David Altshuler, professor of genetics and medicine at Harvard Medical School. Creating a drug to stop a gene from working is less complicated than creating one to turn a gene on, make it go faster, or change how it functions. During the Broad Institute's summer lecture series, Altshuler was explaining the recent discovery of a genetic mutation that protects against type 2 diabetes.

‘Broken genes’ for a broken system

Diabetes discovery illuminates path to new drugs, says HMS professor

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DateJuly 24, 2014April 18, 2019

Nutrition is a balancing act

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DateJune 12, 2014

The Harvard Stem Cell Institute began with a group of about two dozen principal investigators in Harvard’s Schools and affiliated hospitals as a pragmatic solution to a political and funding problem and now is a world leader in the exploding field of stem cell biology.

A decade of breakthroughs

Harvard Stem Cell Institute, initially just an idea, quickly became a generator of scientific discoveries

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DateMay 29, 2014July 9, 2019

Alan Saghatelian (left), associate professor of chemistry and chemical biology, and David Liu, professor of chemistry and chemical biology, have discovered a compound that inhibits insulin-degrading enzyme from breaking down insulin in the body.

Strategy for diabetes treatment

Newly discovered compound slows natural degradation of insulin in body

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DateMay 21, 2014April 17, 2019

Increasing daily coffee consumption may reduce type 2 diabetes risk

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DateApril 29, 2014

New diabetes prevention website launched to stop growing epidemic in Asia

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DateMarch 18, 2014

‘Binge-watching’ TV may be harmful to health

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DateFebruary 26, 2014

HSPH study dispels type 2 diabetes myth

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DateJanuary 17, 2014

Muscle training linked with lowered risk of type 2 diabetes

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DateJanuary 16, 2014

Alessandro Demaio, a Harvard Global Equity Initiative fellow, says the typical person suffering a noncommunicable disease today is a woman under 70, living in poverty, most likely in Asia. To raise awareness of this, Demaio and others started started a global nonprofit named NCDFREE.

Fighting disease on a global scale

Fellow’s nonprofit aims to raise awareness, spur local leadership

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DateJanuary 7, 2014March 18, 2019

Barry Bloom offered reflections on TB research during the “TB in the 21st Century" symposium, which honored HSPH's 100th anniversary (photo 1). Gokhan Hotamisligil, chair of the School’s Department of Genetics and Complex Diseases, focused in part on the obesity epidemic and the link between metabolism and immunity (photo 2), while Associate Professor Sarah Fortune pointed out that the No. 1 risk factor for TB globally was not HIV, but diabetes.

TB’s links to diabetes

Symposium draws researchers to strategize against metabolic diseases

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DateOctober 16, 2013May 10, 2019

Harvard School of Public Health’s Department of Global Health and Population took time to appreciate 50 years of advances during a daylong symposium. HSPH Dean Julio Frenk (at podium), who gave the welcoming remarks, pointed out that anniversaries are important occasions on which to not only reflect on the past, but also refocus on the future.

Giants behind, challenges ahead

HSPH Global Health and Population Department marks 50 years

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DateApril 30, 2013May 31, 2019

“It could eventually mean that instead of taking insulin injections three times a day, you might take an injection of this hormone once a week or once a month, or in the best case maybe even once a year,” said Doug Melton (right). Melton and postdoctoral fellow Peng Yi discovered the hormone betatrophin, which has the potential to improve diabetes treatment.

Potential diabetes breakthrough

Harvard researchers discover hormone that spurs beta cell production; research boosted by federal funding

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DateApril 25, 2013September 11, 2019

“We now can say without question that stopping smoking has a very positive effect on cardiovascular risk for patients with and without diabetes, even if they experience the moderate weight gain seen in this study, which matches post-cessation weight increase reported in other studies,” said Harvard Medical School Associate Professor James Meigs.

Weighing the benefits

Weight gain after quitting smoking doesn't negate cardiovascular benefits

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DateMarch 12, 2013April 9, 2019

HSPH researchers support petition for limits on added sugars in beverages

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DateFebruary 20, 2013

The anti-poverty goal — to halve the proportion of people living in extreme poverty, on less than $1.25 a day — has already been achieved, said Helen Clark, the administrator for the United Nations Development Programme. Much of that success is due to rapid development in China, she told Philip Hilts (left), director of the Knight Science Journalism Fellowships at MIT, adding that it has come at an environmental cost.

Worldwide, women’s inequality

Mortality, poverty remain dogged problems, says U.N. official

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DateFebruary 5, 2013

Researchers throughout the Harvard community are uniting with one goal in mind: to stop the childhood obesity crisis in its tracks. “Childhood obesity is one of the biggest problems in this country,” says Lee Nadler, dean for clinical and translational research at Harvard Medical School and director of Harvard Catalyst.

Health in the balance

Harvard researchers take on obesity epidemic

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DateSeptember 11, 2012June 4, 2019

The no-diet dietitian

Health Services’ Gallant teaches people to trust their gut on food

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DateMarch 22, 2012

The twin epidemics of obesity and its cousin, diabetes, have been the target of numerous studies at Harvard and its affiliated hospitals and institutions. Among seminal findings was the first study to document the extraordinarily tight connection between the two diseases. Research done by Harvard School of Public Health Professor Walter Willett and his colleagues showed that being even slightly overweight increased diabetes risk five times, and being seriously obese increased it 60 times.

Obesity? Diabetes? We’ve been set up

Harvard researchers are targeting obesity and its cousin, diabetes

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DateMarch 7, 2012March 6, 2019

A new diabetes treatment based on a decades-old tuberculosis vaccine has produced promising results in humans, says lead researcher Denise Faustman.

New hope against diabetes

In early trial, drug killed autoimmune cells, raised marker of insulin production

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DateJune 24, 2011

Wynton Marsalis’ appointment is the latest example of the University’s closer embrace of the arts since a presidential task force called in 2008 for a concerted effort to increase the presence of the arts on campus. “I am delighted that Harvard has recognized the need to make cultural literacy an integral part of its curriculum,” Marsalis said. “I hope that other institutions will follow suit to foster a deeper appreciation among all Americans for the democratic victory of our cultural legacy.”

It was a very good year

Harvard's year highlighted by innovation and historical benchmarks

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DateMay 26, 2011July 19, 2019

Work led by MGH researchers offers clues to the development of type 2 diabetes, and may advance detection and treatment methods.

Thinking ahead on diabetes

Research may open path to earlier detection

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DateMarch 22, 2011May 23, 2019

“It’s probably one of the biggest experiments in lifestyle ever conducted in the history of man,” said Associate Professor of Epidemiology Michelle Holmes, with research partner Hans-Olav Adami, Epidemiology Department chair.

Sick to death

Organizers of sweeping study seek to understand Africa’s chronic ailments

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DateDecember 16, 2010

HSPH professor awarded for diabetes research

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DateNovember 22, 2010March 29, 2019

“Just because a country has a bigger burden of infectious disease, that doesn’t mean they have a lesser burden of chronic disease," said Institute of Medicine President Harvey Fineberg. Fineberg delivered his talk, “The Under-appreciated Burden: Chronic Illness in the Developing World,” in conjunction with a reception to highlight a new effort to study chronic disease in Africa.

The rise of chronic disease

As developing nations mature, some illnesses thrive too

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DateNovember 9, 2010April 23, 2019

Mapping the road to obesity

Epigenomics discovery yields new information about fat cells

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DateOctober 14, 2010May 29, 2019

Researchers have found 18 gene sites associated with obesity, and 13 associated with body fat distribution, helping to unravel the riddle of obesity.

Progress on obesity

Gene findings may lead to better treatment

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DateOctober 13, 2010March 13, 2019

Researchers at Harvard Medical School and the Harvard Catalyst have recently selected 12 pioneering ideas for attacking type 1 diabetes, ideas selected through a crowdsourcing experiment called the Challenge. Robynn Sturm (center), assistant deputy chief technology officer at the Office of Science and Technology Policy, speaks with Kevin Dolan (right), HMS's senior human resources consultant, and HMS Dean Jeffrey Flier.

Challenge of finding a cure

Mining the 'wisdom of crowds' to attack disease

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DateSeptember 28, 2010July 18, 2019

The discovery may advance therapies for a variety of diseases — from vaccines that prompt the immune system to stage a sustained assault on cancers, to treatments that derail the onslaught associated with autoimmune diseases.

Poised for progress

Discovery highlights promise of immune system-based therapies

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DateSeptember 17, 2010June 26, 2019

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