They began with a discovery in zebrafish in 2007, and now researchers at the Harvard Stem Cell Institute (HSCI) have published initial results of a Phase Ib human clinical trial of a therapeutic that could improve the success of blood stem cell transplantation. This marks the first time that HSCI has carried a discovery from the lab bench to the clinic.
Targeted nanotherapy is the wave of the medical future, according to Omid Farokhzad, a Harvard Medical School and Brigham and Women’s Hospital researcher who has two nanoparticle-based therapies in clinical trials and a slew of ideas for new ways to put the tiny capsules to work for human health.
Harvard research shows that while only 10 percent of adults with sore throat have strep, the only common cause of sore throat requiring antibiotics, the national antibiotic prescribing rate for adults with sore throat has remained at 60 percent.
As part of a project by Professor Deirdre Barrett to resurrect a study started in 1940, a group of Harvard undergraduates probed the dreams of British officers captured early in World War II and held in a German prison camp.
With a new flu virus appearing in China in April and a new SARS-like respiratory ailment appearing in the Middle East, the Gazette sat down with Harvard epidemiologist Marc Lipsitch to talk about the upcoming flu season.
Harvard researchers have found that the brain uses two largely independent neural circuits to learn spatial and temporal aspects of complex motor skills.
Many modern chronic diseases result from mismatches between how our bodies evolved to be used and how we use them today, Harvard evolutionary biologist Daniel Lieberman writes in a new book.
The key to programming bacteria to follow orders has been found in its protein production. Researchers have learned that by using more rare words, or codons, near the start of a gene, they can remove roadblocks to protein production. The knowledge may mean new drugs and biofuels.
Harvard researchers recently developed the most detailed “specificity profile” for Cas9 — a “machine” made of protein and RNA that can be programmed to target specific DNA sequences and to precisely cut, paste, and turn on or turn off genes. Future researchers will use the data when developing genetic tools and therapies.
People who are married when diagnosed with cancer live longer than those who are not married. Married patients also tended to have cancers diagnosed at an earlier stage, according to Harvard researchers.
Attorneys, judges, scholars and activists interested in expanding health rights through the law were at the Harvard School of Public Health to discuss progress and challenges.
After the U.S. Centers for Disease Control and Prevention issued a report on the threat from drug-resistant bacteria, David Hooper, a physician at Massachusetts General Hospital and an authority on the subject, discussed the issues during a question-and-answer session.
A Harvard study has found that 40 percent of all colorectal cancers might be prevented if people underwent regular colonoscopy screenings. The new research also supports existing guidelines that recommend that people with an average risk of colorectal cancer should have a colonoscopy every 10 years.
Professor Howard Green stumbled across a skin transplant technique that involved growing keratinocytes into full skin layers, making him a pioneer in regenerative medicine.
A panel discussion held by the Forum at Harvard School of Public Health probed the reasons for the modern epidemic of overeating and its particularly harmful effects on children, who are especially susceptible to food marketing.
By synthesizing the data collected in multiple government-sponsored health surveys conducted in recent decades, researchers from the National Bureau of Economic Research, Harvard University, and the University of Massachusetts were able to measure how the quality-adjusted life expectancy of Americans has changed over time.
Removing a woman’s healthy breasts might seem like a radical response to fears of breast cancer. But for women with genetic mutations that put them at high risk of developing the disease, it’s a step that can cut their vulnerability by 90 to 95 percent.
Students from local high schools spent a chunk of the summer at work in a Harvard lab as part of program co-sponsored by the University’s Life Sciences Education program and the Howard Hughes Medical Institute.
A team of researchers at the Wyss Institute has found a way to self-assemble complex structures out of gel “bricks” smaller than a grain of salt. The new method could help solve one of the major challenges in tissue engineering.
Jessica Meir, an assistant professor of anesthesia at Harvard Medical School and Massachusetts General Hospital, is the latest member of the Harvard community given a chance to head to space, joining moon-walkers and Hubble Space Telescope repairmen as she trains to become a NASA astronaut.
A cross-disciplinary team of Harvard scientists, engineers, and clinicians announced Sept. 6 that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer.
In the high-tech laboratory at the Arnold Arboretum’s Weld Hill Research Building, amid an array of expensive, shiny new equipment, sits a 1931 microtome, a machine whose well-oiled parts keep cranking out slices of tissue just 10 micrometers wide, thin enough for light to penetrate and perfect for making slides to see the internal cellular structure of plants.
In the battle against brain cancer, doctors now have a new weapon: an imaging technology that will make brain surgery dramatically more accurate by allowing surgeons to distinguish between brain tissue and tumors, and at a microscopic level.
Harvard researchers have found that people who ate at least two servings each week of certain whole fruits — particularly blueberries, grapes, and apples — reduced their risk for type 2 diabetes by as much as 23 percent in comparison to those who ate less than one serving per month.
A team at the Wyss Institute at Harvard has received a $5.6 million grant from the FDA to use its organs-on-chips technology to test human physiological responses to radiation and evaluate drugs designed to counter those effects.
An international scientific collaborative led by the Harvard Stem Cell Institute’s Kornelia Polyak has discovered why women who give birth in their early 20s are less likely to develop breast cancer than women who don’t, triggering a search for a way to confer this protective state on all women.
The Harvard Allston Education Portal on Thursday hosted a workshop examining the effects of gluten on health, with Jennifer Zartarian of Cambridge Health Associates answering questions and acting as a guide through the latest research.
Scientists at Harvard-affiliated Dana-Farber Cancer Institute observed a strong and selective immune response in some patients who received several doses of a “personalized” tumor vaccine composed of their own inactivated leukemia cells combined with an immune stimulant.
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