Harvard researchers working at the Broad Institute of MIT and Harvard have uncovered nine rare genetic mutations that dramatically increase the risk of developing type 2 diabetes. The discovery of the mutations highlights the dizzying genetic diversity of a disease rapidly spreading around the world.
A Harvard Stem Cell Institute study comparing how blood stem cells and leukemia cells consume nutrients found that cancer cells are far less tolerant of shifts in their energy supply than their normal counterparts. The results suggest there could be ways to target and kill cancer cells without affecting healthy cells.
The fight to end the Ebola epidemic is not just about saving lives, it’s also about heading off a potentially broader humanitarian crisis, according to a Harvard Kennedy School panel.
Researchers uncovered a variety of features in the genomes of five species of African cichlid fish that enabled them to thrive in new habitats and ecological niches. The findings from these “natural mutants” shed new light on the molecular process of evolution in all vertebrate species.
Harvard scientists have developed a new test for sickle cell disease that provides results in just 12 minutes and costs as little as 50 cents — far faster and cheaper than other tests.
Dietary quality in the United States has improved steadily in recent years, but overall dietary quality remains poor and disparities continue to widen among socioeconomic and racial/ethnic groups, according to a new study from the Harvard School of Public Health.
A team of researchers from the Broad Institute, Harvard University, and elsewhere has sequenced and analyzed dozens of Ebola virus genomes in the present outbreak. Their findings could have important implications for rapid field diagnostic tests.
Researchers at Harvard-affiliated McLean Hospital are reporting that xenon gas, used in humans for anesthesia and diagnostic imaging, has the potential to be a treatment for post-traumatic stress disorder (PTSD) and other memory-related disorders
In the Hunnewell Building is the Arnold Arboretum Horticultural Library, whose books, papers, and photographs ― stored near living collections of many of the same plants they describe ― draw scholars from around the world.
A new study conducted by Harvard scientists shows that in deer mice, a species known to be highly promiscuous, sperm clump together to swim in a more linear fashion, increasing their chances of fertilization.
The protective gear needed to get Sierra Leone’s health clinics reopened, coupled with public education about the Ebola epidemic, are the greatest areas of need, according to a Harvard Fulbright Fellow and physician from Sierra Leone.
Though the threat to the U.S. population from the Ebola outbreak in West Africa is low, the need in epidemic countries is great, says Michael VanRooyen, director of the Harvard Humanitarian Initiative.
In pre-clinical studies conducted by the researchers, a one-time, local injection of the hydrogel-drug combo prevented graft rejection for more than 100 days. This compared with 35.5 days for recipients receiving only tacrolimus, and 11 days for recipients without treatment or only receiving hydrogel.
Using genetic tools to implant genes that produce fluorescent proteins in the DNA of transparent C. elegans worms, Harvard scientists have been able to shed light on neuron-specific “alternative splicing,” a process that allows a single gene to produce many different proteins.
Studies begun by Harvard Stem Cell Institute scientists eight years ago have led to a report that may be a major step in developing treatments for amyotrophic lateral sclerosis, or Lou Gehrig’s disease.
Harvard researchers have joined with counterparts in the U.S. and Botswana governments to conduct a major evaluation of AIDS treatment targeted specifically to reduce infectivity.
Children born with so-called “bubble boy” disease have the best chance of survival if they undergo a hematopoietic stem cell transplant as soon after birth as possible, according to a detailed analysis of 10 years of outcome data by researchers at the Harvard-affiliated Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.
A new study shows that boosting inhibitory neurotransmission early in brain development can help reverse deficits in inhibitory circuit maturation that are associated with autism.
In a study at Harvard-affiliated McLean Hospital, individuals with major depressive disorder or bipolar disorder who received low-field magnetic stimulation (LFMS) showed immediate and substantial mood improvement.
Bauer Fellow Rachel Dutton has identified three general types of microbial communities that live on cheese, opening the door to using each as a “model” community for the study of whether and how various microbes and fungi compete or cooperate as they form communities, as well as what molecules and mechanisms are involved in the process.
To David Altshuler, the recent discovery of a genetic mutation that protects against type 2 diabetes offers hope in fighting more than just diabetes. It also illustrates how using the…
The largest-ever phylogenetic spider study shows that, contrary to popular opinion, the two groups of spiders that weave orb-shaped webs do not share a single origin.
Philanthropist Ted Stanley announced plans to donate $650 million to the Broad Institute of Harvard and MIT to foster research into psychiatric diseases, whose biological causes, long a mystery, scientists have begun to tease out in recent years.
Harvard-affiliated researchers joined an international team to identify more than 100 locations in the human genome associated with the risk of developing schizophrenia in what is the largest genomic study published on any psychiatric disorder to date.
A new technique for observing neural activity will allow scientists to stimulate neurons and observe their firing pattern in real time. Tracing those neural pathways can help researchers answer questions about how neural signals propagate, and could one day allow doctors to design individualized treatments for a host of disorders.