For roughly 2,000 years, Chinese herbalists have treated malaria using a root extract, commonly known as chang shan, from a type of hydrangea that grows in Tibet and Nepal. More recent studies suggest that halofuginone, a compound derived from this extract’s bioactive ingredient, could be used to treat many autoimmune disorders as well. Now, researchers from the Harvard School of Dental Medicine have discovered the molecular secrets behind this herbal extract’s power.
Experiments conducted in a Harvard lab reveal that, while sharks’ sandpaperlike skin does allow the animals to swim faster and more efficiently, the structure of some high-tech swimsuits has no effect when it comes to reducing drag as swimmers move through the water.
Synaptic plasticity — the ability of the synaptic connections between the brain’s neurons to change and modify over time — has been shown to be a key to memory formation and the acquisition of new learning behaviors. Now research reveals that the neural circuits controlling hunger and eating behaviors are also controlled by plasticity.
Researchers in a Harvard lab have developed a device, dubbed LADY GAGA, that allows them for the first time to precisely control airborne scents. They have used the device in their work unraveling how animals make navigational decisions based on their environment.
A study by Harvard-affiliated Dana-Farber Cancer Institute finds that most terminally ill cancer patients discuss end-of-life care with physicians but that such discussions often occur late in their illness.
As science wrestles with the problem of how life arose on Earth, hindsight shows that seemingly intractable obstacles can have simple, even elegant solutions, said Nobel laureate Jack Szostak.
Biophysicist Aravinthan Samuel has developed new techniques to monitor and influence the behavior of roundworms to learn how their basic nervous systems work, a first step to understanding the circuitry in more complex creatures, like humans.
Harvard researchers have been at the forefront of many battles against devastating diseases, leading pivotal breakthroughs against scourges from 1800 to the present.
Now 74 years young, the Harvard Study of Adult Development continues to yield a treasure trove of data about how people behave, and change — including predictions of strong indicators to a happy life.
The Eli and Edythe L. Broad Institute of Harvard and MIT today announced that it has received a $32.5 million grant from the Boston-based Klarman Family Foundation to support a new collaborative effort focused on deciphering how human cells are wired.
Perfluorinated compounds (PFCs), widely used in manufactured products such as non-stick cookware, waterproof clothing, and fast-food packaging, were associated with lowered immune response to vaccinations in children in research led by Philippe Grandjean of the Harvard School of Public Health.
Dozens of Harvard undergraduates started the year with a new emphasis on wellness, thanks to the Optimal Health program. With presentations from a lifestyle medicine consultant, a nutritionist, a personal trainer, a sleep specialist, and a stress manager, Optimal Health emphasized prevention and fitness.
Color-coded food labeling and adjusting the way food items are positioned in display cases encouraged healthy choices in a large hospital cafeteria in a study by MGH researchers.
Harvard scientists have developed the fullest picture yet of how neurons in the brain interact to reinforce behaviors that range from learning to drug use, a finding that could open the door to new treatments for addiction.
A new study from Harvard-affiliated Beth Israel Deaconess Medical Center finds that a group of little-explored cells in the tumor microenvironment likely serves as an important gatekeeper against cancer progression and metastasis.
Nutrition experts at HSPH and chefs and dietitians at the Culinary Institute of America have developed five muffin recipes that incorporate healthy fats and whole grains, and use a lighter hand on the salt and sugar.
Research collaboration between the Wyss Institute for Biologically Inspired Engineering at Harvard University and Children’s Hospital Boston has developed “smart” injectable nanotherapeutics that can be programmed to selectively deliver drugs to the cells of the pancreas.
A team led by researchers at Harvard-affiliated Dana-Farber Cancer Institute has isolated a natural hormone from muscle cells that triggers some of the key health benefits of exercise.
Harvard researchers have found that a tiny motor inside of us called dynein, one tasked with shuttling vital payloads throughout the cell’s intricate highway infrastructure, staggers, which is quite contrary to the regular, efficient poise of its fellow motors.
In a new study, Harvard stem cell researchers and scientists at the University of Cambridge have found that the age-related degeneration in conditions such as multiple sclerosis (MS) may be reversible.
John Huth, the creator of the popular “Primitive Navigation” course, spent most of last summer investigating a mysterious phenomenon called “underwater lightning,” which some say can be used as a navigational tool.
Efforts to halt the growing abuse of prescription drugs must include addressing the availability of these drugs on the Internet and increasing physician awareness of the dangers posed by Internet pharmacies.
With health care costs set to gobble up more of the federal budget, analysts say that additional reforms are inevitable, though national indecision over what they should look like could mean a rocky path ahead.
Harvard researchers have found a treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington’s disease and other neurodegenerative disorders.
A new study led by Harvard School of Public Health researchers provides a novel explanation as to why some tuberculosis cells are inherently more difficult to treat with antibiotics.
Ninety instructors and junior faculty members at Harvard Medical School have received fellowships from the Eleanor and Miles Shore 50th Anniversary Fellowship Program for Scholars in Medicine. The program provides grants for recipients to hire lab help or to gain protected time by easing clinical duties.
The first-of-its-kind strategy is credited for curing at least five of 10 children at a rural Rwandan hospital; two others are in remission while receiving chemotherapy, and three children have died. The long-distance team approach was designed by Harvard Medical School instructor in medicine Sara Stulac, director of pediatrics for Partners In Health.
Featured series 
