Tag: Donald Ingber

  • Nation & World

    DNA, assemble

    A concept for seeded all-or-nothing assembly of micron-scale DNA nanostructures that could extend nanofabrication capabilities and enable creation of highly specific diagnostics.

    7 minutes
    William Shih.
  • Nation & World

    Better vaccines are in our blood

    New platform technology uses red blood cells to generate targeted immune responses in mice

    6 minutes
    Syringe in vaccine bottle.
  • Nation & World

    Blood-brain barrier chip performs human-like drug and antibody transport

    Wyss Institute scientists have developed chip technology that mimics the blood-brain barrier in humans. The new models will help researchers study drugs to treat cancer, neurodegeneration, and other diseases of the central nervous system.

    7 minutes
    A transparent plastic model of a human skull
  • Nation & World

    Wyss donates third major gift

    The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today the latest gift of $131 million from its founder, entrepreneur and philanthropist Hansjörg Wyss, M.B.A. ’65.

    9 minutes
  • Nation & World

    A step closer to tissue-engineered kidneys

    The Wyss Institute and Roche Innovation Center Basel in Switzerland have teamed up to create 3-D bioprinted proximal tubules beside functioning blood vessel compartments, closely mimicking the kidney’s blood-filtration system that removes waste products while returning “good” molecules, such as glucose and amino acids, back into the bloodstream.

    5 minutes
  • Nation & World

    Harnessing nature to beat cancer

    Every year, more than 18 million people around the world are told, “You have cancer.” In the U.S., nearly half of all men and more than one-third of women will…

    18 minutes
    Nanoparticles
  • Nation & World

    Creating a smoking machine

    Researchers at Harvard’s Wyss Institute have developed an instrument that smokes cigarettes like a human, and delivers whole smoke to the air space of microfluidic human airway chips. The machine may enable new insights into how nonsmokers and COPD patients respond to smoke.

    5 minutes
  • Nation & World

    Creating 3-D tissue and its potential for regeneration

    “This latest work extends the capabilities of our multi-material bioprinting platform to thick human tissues, bringing us one step closer to creating architectures for tissue repair and regeneration,” says the study’s senior author, Jennifer A. Lewis of both the Wyss Institute and Harvard’s Paulson School for Engineering and Applied Sciences.

    4 minutes
  • Nation & World

    Blood clot breakthrough uses drug-device combo

    Harvard-affiliated researchers are working on a procedure that will allow fully obstructed blood clots in the brain to be cleared using a device that opens a small channel through the blockage, which combines with a clot-busting drug to target the obstructed site.

    4 minutes
  • Nation & World

    Wyss improves sepsis device

    Scientists at the Wyss Institute have improved a device developed last year to treat sepsis that works by mimicking the human spleen. The new device is better positioned for near-term use in clinics.

    5 minutes
  • Nation & World

    Bacteria ‘factories’ churn out valuable chemicals

    A team of researchers led by Harvard geneticist George Church at the Wyss Institute for Biologically Inspired Engineering and Harvard Medical School has made big strides toward a future in which the predominant chemical factories of the world are colonies of genetically engineered bacteria.

    3 minutes
  • Nation & World

    Wyss Institute’s organs-on-chips develops into new company

    The Wyss Institute for Biologically Inspired Engineering at Harvard University announced on Monday that its human organs-on-chips technology will be commercialized by a newly formed private company to accelerate the development of pharmaceutical, chemical, cosmetic, and personalized medicine products.

    3 minutes
  • Nation & World

    Sharper image

    Harvard’s Wyss Institute has found a new DNA-based, super-resolution microscopy method that could simultaneously spot dozens of distinct types of biomolecules. This could potentially lead to new ways to diagnose disease, track its prognosis, or monitor the effectiveness of therapies at a cellular level.

    4 minutes
  • Nation & World

    Measuring life’s tugs and nudges

    Harvard scientists have devised the first method to measure the push and pull of cells as embryonic tissue develops. The cells’ tiny forces are measured in 3-D tissues and living embryos.

    4 minutes
  • Nation & World

    Cancer vaccine begins Phase I clinical trials

    A cross-disciplinary team of Harvard scientists, engineers, and clinicians announced Sept. 6 that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer.

    3 minutes
  • Nation & World

    A year of change, month by month

    2012-13 was a year of inventions and ascensions, elections and projections, digitizing and prioritizing. The University also launched HarvardX, the wildly popular web learning platform.

    22 minutes
  • Nation & World

    Lung-on-a-Chip wins prize

    Wyss Institute Founding Director Donald Ingber received the NC3Rs 3Rs Prize from the U.K.’s National Centre for the Replacement, Refinement, and Reduction of Animals in Research for his innovative Lung-on-a-Chip.

    1 minute
  • Nation & World

    Building with DNA bricks

    Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created more than 100 3-D nanostructures using DNA building blocks that function like Lego bricks — a major advance from the two-dimensional structures the same team built a few months ago.

    3 minutes
  • Nation & World

    New way to model human disease

    Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have mimicked pulmonary edema in a microchip lined by living human cells. They used this “lung-on-a-chip” to study drug toxicity and identify potential new therapies to prevent this life-threatening condition.

    5 minutes
  • Nation & World

    Smart suit improves physical endurance

    Harvard’s Wyss Institute for Biologically Inspired Engineering announced that it has received a $2.6 million contract from the Defense Advanced Research Projects Agency (DARPA) to develop a smart suit that helps improve physical endurance for soldiers in the field.

    2 minutes
  • Nation & World

    Clot-busting technology goes straight to work

    Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard have developed a novel biomimetic strategy that delivers life-saving nanotherapeutics directly to obstructed blood vessels, dissolving blood clots before they cause serious damage or even death.

    3 minutes
  • Nation & World

    Using nature to inspire robotics

    The annual symposium of the Wyss Institute for Biologically Inspired Engineering, held at Harvard Medical School, prompted a spirited discussion on robotics and medicine, with nature as a model.

    3 minutes
  • Nation & World

    Using DNA as bricks and mortar

    Researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering have figured out how to use short lengths of DNA as physical, rather than genetic, building blocks, creating letters and other shapes from the molecules in a proof of design that could one day lead to the creation of structures that, among other things, deliver drugs…

    3 minutes
  • Nation & World

    A time was had by all

    A fond look back at the memorable events of Harvard’s 375th year.

    16 minutes
  • Nation & World

    Sending DNA robot to do the job

    Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a robotic device made from DNA that could potentially seek out specific cell targets within a complex mixture of cell types and deliver important molecular instructions, such as telling cancer cells to self-destruct or programming immune responses.

    5 minutes
  • Nation & World

    As strong as an insect’s shell

    Wyss Institute scientists have created a material that mimics the hard outer skin of bugs. The result is low-cost and easily manufactured, and tough. It eventually might provide a more environmentally friendly alternative to plastic.

    4 minutes
  • Nation & World

    Donald Ingber wins 2011 Holst Medal

    Donald Ingber, the Judah Folkman Professor of Vascular Biology at Harvard Medical School and founding director of the Wyss Institute for Biologically Inspired Engineering, has been awarded the 2011 Holst Medal.

    1 minute
  • Nation & World

    Wyss Institute project targets sepsis

    The Wyss Institute for Biologically Inspired Engineering at Harvard has been awarded a $12.3 million, four-year grant from the Defense Advanced Research Projects Agency to develop a treatment for sepsis, a commonly fatal bloodstream infection.

    3 minutes
  • Nation & World

    Bucky on stage

    Inventor and futurist R. Buckminster Fuller, thrown out of Harvard College twice in the early 20th century, returns in the center of a one-man play on the “history (and mystery) of the universe.”

    5 minutes
  • Nation & World

    Living, breathing human lung-on-a-chip

    Researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering have created a device that mimics a living, breathing human lung on a microchip. The device, about the size of a rubber eraser, acts much like a lung in a human body and is made using human lung and blood vessel cells.

    5 minutes