Featured series 
Tag: Howard Hughes Medical Institute
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Nation & World
7 from Harvard among new Howard Hughes Medical Institute investigators
Seven Harvard affiliates are among 33 scientists from across the United States to be appointed as investigators by the Howard Hughes Medical Institute.
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Nation & World
New gene-editing technique shows promise against sickle cell disease
Scientists at Harvard and the Broad Institute have demonstrated that it is possible to treat sickle cell disease in mice using a new gene-editing technique.
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Nation & World
A ‘miracle poison’ for novel therapeutics
Researchers prove they can engineer proteins to find new targets with high selectivity, a critical advance toward potential new treatments to help neuroregeneration, cytokine storm.
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Nation & World
Innovative tool offers hope for children with rapid-aging disease
Several hundred children worldwide live with progeria, a deadly premature aging disease.
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Nation & World
A promise to a friend
Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.
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Nation & World
Science at the speed of ‘light-sheet’
Combining two recently developed technologies — expansion microscopy and lattice light-sheet microscopy — researchers have developed a method that yields high-resolution visualizations of large volumes of brain tissue, at speeds roughly 1,000 times faster than other methods.
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Nation & World
Ten from Harvard named HHMI Faculty Scholars
Ten Harvard scientists have won the support of a new funding initiative by the Howard Hughes Medical Institute, the Simons Foundation, and the Gates Foundation.
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Nation & World
Harvard biologist is first woman to lead HHMI
Erin O’Shea, the Paul C. Mangelsdorf Professor of Molecular and Cellular Biology and of Chemistry and Chemical Biology, has been named the sixth president of the Howard Hughes Medical Institute.
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Nation & World
Potential diabetes treatment advances
Researchers at MIT’s David H. Koch Institute for Integrative Cancer Research, in collaboration with scientists at the Harvard Stem Cell Institute and several other institutions, have developed an implantable device that in mice shielded insulin-producing beta cells from immune system attack for six months — a substantial proportion of life span.
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Nation & World
Three appointed as investigators
Howard Hughes Medical Institute appoints Levi Garraway, Pardis Sabeti, and Tobias Walther as investigators.
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Nation & World
Andrew Murray named an HHMI professor
Professor Andrew Murray was named a Howard Hughes Medical Institute professor and will receive $1 million in funding for innovation in undergraduate science education.
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Nation & World
New hope in regenerative medicine
Harvard Stem Cell Institute researchers at Boston Children’s Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells have the functional hallmarks of HSCs and are able to self-renew like those cells.
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Nation & World
‘Junk?’ Not so fast
Research by Harvard Stem Cell Institute scientists shows that much lincRNA, which had been generally believed useless, plays an important role in the genome.
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Nation & World
Summer in the lab
Students from local high schools spent a chunk of the summer at work in a Harvard lab as part of program co-sponsored by the University’s Life Sciences Education program and the Howard Hughes Medical Institute.
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Nation & World
New investigators named
Adam Cohen, professor of chemistry and chemical biology and of physics, and Hopi Hoekstra, professor of organismic and evolutionary biology and molecular and cellular biology, are among the 27 scientists nationwide to be appointed as investigators by the Howard Hughes Medical Institute.
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Nation & World
Potential diabetes breakthrough
Researchers at the Harvard Stem Cell Institute have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated 26 million Americans.
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Nation & World
Warren E.C. Wacker dies
Warren E.C. Wacker, former Henry K. Oliver Professor of Hygiene Emeritus, died on Dec. 29, 2012.
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Nation & World
HHMI taps Erin O’Shea
Erin K. O’Shea, the director of the FAS Center for Systems Biology, has accepted the position of vice president and chief scientific officer of the Howard Hughes Medical Institute. She will also maintain her lab and involvement at Harvard.
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Nation & World
The early days of discovery
A recipient of this year’s Nobel Prize in chemistry investigated the workings of cell receptors, the basis of his groundbreaking research involving the complex process of how the body’s cells communicate and interact, while a young medical resident at Harvard.
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Nation & World
Three GSAS among winners of HHMI fellowships
Three Graduate School of Arts and Sciences students — Nataly Moran Cabili, Mehmet Fisek, and Le Cong — are among the 48 winners in a new fellowship competition from the Howard Hughes Medical Institute.
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Nation & World
Dialing down sickle cell disease
Flipping a single molecular switch can reverse illness in an animal model of sickle cell disease, according to a study by Harvard researchers at Children’s Hospital Boston and Dana-Farber Cancer Institute.
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Nation & World
Animal scents
A Harvard study of how mice respond to scent cues from potential mates, competitors, and nearby predators has laid a foundation for further investigations that may eventually lead to a greater understanding of social recognition in the animal brain, with implications for a host of human disorders ranging from autism to post-traumatic stress disorder.
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Nation & World
RNA dynamics deconstructed
RNA plays a critical role in directing the creation of proteins, but there is more to the life of an RNA molecule than simply carrying DNA’s message.
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Nation & World
Better blood
An innovative experimental treatment for boosting the effectiveness of blood stem-cell transplants with umbilical cord blood has a favorable safety profile in long-term animal studies, according to Harvard Stem Cell Institute scientists at Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, and Children’s Hospital Boston.
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Nation & World
Speeding up biomolecular evolution
Scientists at Harvard University have harnessed the prowess of fast-replicating bacterial viruses, also known as phages, to accelerate the evolution of biomolecules in the laboratory.
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Nation & World
Brain changes found in normal elders
Harvard-affiliated researchers using two brain-imaging technologies have found that apparently normal older individuals with brain deposits of amyloid beta — the primary constituent of the plaques found in the brains of Alzheimer’s disease patients — also had changes in brain structure similar to those seen in Alzheimer’s patients.
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Nation & World
Multiple myeloma genome unveiled
Harvard scientists have unveiled the most comprehensive picture to date of the full genetic blueprint of multiple myeloma, a form of blood cancer.
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Nation & World
Genes tied to prostate cancer uncovered
For the first time, researchers have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease.
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Nation & World
Throwing a genetic switch
Study finds that maternal genes in mice predominate in the developing brain, while paternal genes gain the upper hand in adulthood. Researchers also find 1,300 imprinted genes in the brain, far more than previously known.
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Nation & World
House masters appointed
Harvard College Dean Evelynn M. Hammonds, announced the appointment of three House masters: Douglas Melton, Christie McDonald, and Rakesh Khurana.
