Tag: Doug Melton

  • Nation & World

    Forward thinking

    Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.

    6 minutes
    Scientists
  • Nation & World

    Medical hope on horizon

    Stem cell science is accelerating development of therapies for diabetes, ALS, other diseases, researchers tell HUBweek sessions.

    9 minutes
  • Nation & World

    First area cell transplantation center

    An expansive effort by several Harvard-affiliated units and hospitals has created the first cell transplantation center in the Boston area.

    4 minutes
  • Nation & World

    Potential diabetes treatment advances

    Researchers at MIT’s David H. Koch Institute for Integrative Cancer Research, in collaboration with scientists at the Harvard Stem Cell Institute and several other institutions, have developed an implantable device that in mice shielded insulin-producing beta cells from immune system attack for six months — a substantial proportion of life span.

    3 minutes
  • Nation & World

    Hope against disease targeting children

    Harvard Stem Cell Institute researchers studying spinal muscular atrophy have found molecular changes that help trigger the genetic disease in children.

    4 minutes
  • Nation & World

    Innovative faculty research receives support

    Five winners have been named as recipients of this year’s Star Family Challenge for Promising Scientific Research awards. Now in its second year, the challenge is designed to acknowledge and support some of the most innovative research being done by Harvard faculty in the natural and social sciences.

    6 minutes
  • Nation & World

    Brains or skin?

    A protein that is necessary for the formation of the vertebrate brain has been identified by researchers at the Harvard Stem Cell Institute (HSCI) and Boston Children’s Hospital, in collaboration with scientists from Oxford and Rio de Janeiro.

    2 minutes
  • Nation & World

    A pill to shed fat?

    Harvard Stem Cell Institute researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity.

    5 minutes
  • Nation & World

    Reprogramming cells, long term

    Harvard Stem Cell Institute researchers have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. The work is an important advance in the effort to develop cell-based therapies for tissue repair, and specifically in the effort to develop improved treatment for diabetes.

    5 minutes
  • Nation & World

    Giant leap against diabetes

    Harvard stem cell researchers announced a giant leap forward in the quest to find a truly effective treatment for type 1 diabetes, a disease that affects an estimated 3 million Americans.

    7 minutes
  • Nation & World

    Harvard Management Company turns 40

    University and Harvard Management Company officials gathered Thursday to mark the anniversary of the latter’s founding, which made Harvard one of the first universities with a specialized organization to oversee its institutional investments.

    5 minutes
  • Nation & World

    A decade of breakthroughs

    The Harvard Stem Cell Institute is now 10 years old. What began as an idea embracing cross-disciplinary research quickly became a generator of scientific discoveries.

    4 minutes
  • Nation & World

    Hope for aging brains, skeletal muscle

    Researchers at the Harvard Stem Cell Institute have shown that a protein, one they previously demonstrated can make failing hearts in aging mice appear more like those of young and healthy mice, similarly improves brain and skeletal muscle function in aging mice.

    7 minutes
  • Nation & World

    Quality control

    A Harvard research team led by Kevin Kit Parker, a Harvard Stem Cell Institute principal faculty member, has identified a set of 64 crucial parameters by which to judge stem cell-derived cardiac myocytes, making it possible for scientists and pharmaceutical companies to quantitatively judge and compare the value of stem cells.

    4 minutes
  • Nation & World

    Making old hearts younger

    Two Harvard Stem Cell Institute researchers have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for the form of age-related heart failure that affects millions of Americans, a study says.

    7 minutes
  • Nation & World

    Potential diabetes breakthrough

    Researchers at the Harvard Stem Cell Institute have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated 26 million Americans.

    8 minutes
  • Nation & World

    New avenue in neurobiology

    Harvard stem cell biologists have proven that it is possible to turn one type of already differentiated neuron into another inside the brain, and their findings may have enormous implications for the treatment of neurodegenerative diseases.

    4 minutes
  • Nation & World

    Architecture of experience

    Harvard’s distinctive House system, a baker’s dozen of smaller communities, nurtures undergrads to find their passions, and themselves.

    17 minutes
  • Nation & World

    Big advance against cystic fibrosis

    Harvard stem cell researchers at Massachusetts General Hospital have taken a critical step toward discovering in the relatively near future a drug to control cystic fibrosis, a fatal lung disease that claims about 500 lives each year, with 1,000 new cases diagnosed annually.

    7 minutes
  • Nation & World

    Bench to Bedside – Innovation at Harvard

    Harvard researchers and clinicians collaborate across disciplines and around the globe to craft solutions to the world’s toughest health challenges.

    1 minute
  • Nation & World

    Funding success, and finding it

    Four years ago, Harvard’s Office of Technology Development launched its Accelerator Fund, a $10 million revolving account to be used as a bridge across the “valley” between creation and development. The fund is proving to be just such a bridge.

    6 minutes
  • Nation & World

    Stimulating Cells – Doug Melton – Harvard Thinks Big

    Doug Melton Thomas Dudley Cabot Professor of the Natural Sciences at Harvard University and co-Director of the Harvard Stem Cell Institute

    1 minute
  • Nation & World

    A gift that spans Schools

    Siddhartha Yog, M.B.A. ’04, founder and managing partner of The Xander Group Inc., has given Harvard $11,000,001 to establish two professorships, fellowships and financial aid, and an intellectual entrepreneurship fund.

    7 minutes
  • Nation & World

    Harvard’s startup upstart

    Gordon Jones, director of the new Harvard Innovation Lab, has ideas on how to foster an entrepreneurial mentality at the country’s oldest university.

    5 minutes
  • Nation & World

    Stem cell lessons

    Five years after first gaining institutional permission to attempt to produce stem cell lines via somatic cell nuclear transfer (SCNT), two Harvard researchers and a former Harvard postdoctoral fellow have closed the loop with a flurry of new studies and a commentary in several leading journals.

    4 minutes
  • Nation & World

    A look inside: Eliot House

    Named in honor of Charles William Eliot, president of Harvard from 1869 to 1909, Eliot House was opened in 1931. It was one of the original seven Houses at the College following the plan by Eliot’s successor, Abbot Lawrence Lowell, to “revitalize education and revive egalitarianism at Harvard College.”

    1 minute
  • Nation & World

    On summer break, a poem

    An undergraduate on summer break is inspired to write a poem celebrating Harvard’s 375th anniversary.

    6 minutes
  • Nation & World

    From skin cells to motor neurons

    Harvard stem cell researchers have succeeded in reprogramming adult mouse skin cells directly into the type of motor neurons damaged in amyotrophic lateral sclerosis, best known as Lou Gehrig’s disease, and spinal muscular atrophy.

    4 minutes
  • Nation & World

    Two studies prove value of iPS cells

    A team of Harvard Stem Cell Institute (HSCI) researchers, in collaboration with scientists at Columbia University, have demonstrated that many iPS cells (stem cells created by reprogramming adult cells) are the equal of human embryonic stem cells in creating human motor neurons, the cells destroyed in a number of neurological diseases, including Parkinson’s.

    3 minutes
  • Nation & World

    Hyman to step down as provost

    Provost Steven E. Hyman, who spurred an expansion of interdisciplinary research at Harvard and has overseen the revitalization of the University’s libraries and many of its museums and cultural institutions, plans to leave his post after nearly a decade.

    6 minutes