Tag: Doug Melton
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Nation & World
Forward thinking
Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.
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Nation & World
Medical hope on horizon
Stem cell science is accelerating development of therapies for diabetes, ALS, other diseases, researchers tell HUBweek sessions.
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Nation & World
First area cell transplantation center
An expansive effort by several Harvard-affiliated units and hospitals has created the first cell transplantation center in the Boston area.
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Nation & World
Potential diabetes treatment advances
Researchers at MIT’s David H. Koch Institute for Integrative Cancer Research, in collaboration with scientists at the Harvard Stem Cell Institute and several other institutions, have developed an implantable device that in mice shielded insulin-producing beta cells from immune system attack for six months — a substantial proportion of life span.
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Nation & World
Hope against disease targeting children
Harvard Stem Cell Institute researchers studying spinal muscular atrophy have found molecular changes that help trigger the genetic disease in children.
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Nation & World
Innovative faculty research receives support
Five winners have been named as recipients of this year’s Star Family Challenge for Promising Scientific Research awards. Now in its second year, the challenge is designed to acknowledge and support some of the most innovative research being done by Harvard faculty in the natural and social sciences.
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Nation & World
Brains or skin?
A protein that is necessary for the formation of the vertebrate brain has been identified by researchers at the Harvard Stem Cell Institute (HSCI) and Boston Children’s Hospital, in collaboration with scientists from Oxford and Rio de Janeiro.
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Nation & World
A pill to shed fat?
Harvard Stem Cell Institute researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity.
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Nation & World
Reprogramming cells, long term
Harvard Stem Cell Institute researchers have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. The work is an important advance in the effort to develop cell-based therapies for tissue repair, and specifically in the effort to develop improved treatment for diabetes.
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Nation & World
Giant leap against diabetes
Harvard stem cell researchers announced a giant leap forward in the quest to find a truly effective treatment for type 1 diabetes, a disease that affects an estimated 3 million Americans.
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Nation & World
Harvard Management Company turns 40
University and Harvard Management Company officials gathered Thursday to mark the anniversary of the latter’s founding, which made Harvard one of the first universities with a specialized organization to oversee its institutional investments.
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Nation & World
A decade of breakthroughs
The Harvard Stem Cell Institute is now 10 years old. What began as an idea embracing cross-disciplinary research quickly became a generator of scientific discoveries.
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Nation & World
Hope for aging brains, skeletal muscle
Researchers at the Harvard Stem Cell Institute have shown that a protein, one they previously demonstrated can make failing hearts in aging mice appear more like those of young and healthy mice, similarly improves brain and skeletal muscle function in aging mice.
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Nation & World
Quality control
A Harvard research team led by Kevin Kit Parker, a Harvard Stem Cell Institute principal faculty member, has identified a set of 64 crucial parameters by which to judge stem cell-derived cardiac myocytes, making it possible for scientists and pharmaceutical companies to quantitatively judge and compare the value of stem cells.
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Nation & World
Potential diabetes breakthrough
Researchers at the Harvard Stem Cell Institute have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated 26 million Americans.
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Nation & World
New avenue in neurobiology
Harvard stem cell biologists have proven that it is possible to turn one type of already differentiated neuron into another inside the brain, and their findings may have enormous implications for the treatment of neurodegenerative diseases.
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Nation & World
Architecture of experience
Harvard’s distinctive House system, a baker’s dozen of smaller communities, nurtures undergrads to find their passions, and themselves.
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Nation & World
Big advance against cystic fibrosis
Harvard stem cell researchers at Massachusetts General Hospital have taken a critical step toward discovering in the relatively near future a drug to control cystic fibrosis, a fatal lung disease that claims about 500 lives each year, with 1,000 new cases diagnosed annually.
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Nation & World
Bench to Bedside – Innovation at Harvard
Harvard researchers and clinicians collaborate across disciplines and around the globe to craft solutions to the world’s toughest health challenges.
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Nation & World
Funding success, and finding it
Four years ago, Harvard’s Office of Technology Development launched its Accelerator Fund, a $10 million revolving account to be used as a bridge across the “valley” between creation and development. The fund is proving to be just such a bridge.
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Nation & World
Stimulating Cells – Doug Melton – Harvard Thinks Big
Doug Melton Thomas Dudley Cabot Professor of the Natural Sciences at Harvard University and co-Director of the Harvard Stem Cell Institute
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Nation & World
A gift that spans Schools
Siddhartha Yog, M.B.A. ’04, founder and managing partner of The Xander Group Inc., has given Harvard $11,000,001 to establish two professorships, fellowships and financial aid, and an intellectual entrepreneurship fund.
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Nation & World
Harvard’s startup upstart
Gordon Jones, director of the new Harvard Innovation Lab, has ideas on how to foster an entrepreneurial mentality at the country’s oldest university.
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Nation & World
Stem cell lessons
Five years after first gaining institutional permission to attempt to produce stem cell lines via somatic cell nuclear transfer (SCNT), two Harvard researchers and a former Harvard postdoctoral fellow have closed the loop with a flurry of new studies and a commentary in several leading journals.
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Nation & World
A look inside: Eliot House
Named in honor of Charles William Eliot, president of Harvard from 1869 to 1909, Eliot House was opened in 1931. It was one of the original seven Houses at the College following the plan by Eliot’s successor, Abbot Lawrence Lowell, to “revitalize education and revive egalitarianism at Harvard College.”
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Nation & World
On summer break, a poem
An undergraduate on summer break is inspired to write a poem celebrating Harvard’s 375th anniversary.
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Nation & World
From skin cells to motor neurons
Harvard stem cell researchers have succeeded in reprogramming adult mouse skin cells directly into the type of motor neurons damaged in amyotrophic lateral sclerosis, best known as Lou Gehrig’s disease, and spinal muscular atrophy.
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Nation & World
Two studies prove value of iPS cells
A team of Harvard Stem Cell Institute (HSCI) researchers, in collaboration with scientists at Columbia University, have demonstrated that many iPS cells (stem cells created by reprogramming adult cells) are the equal of human embryonic stem cells in creating human motor neurons, the cells destroyed in a number of neurological diseases, including Parkinson’s.
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Nation & World
Hyman to step down as provost
Provost Steven E. Hyman, who spurred an expansion of interdisciplinary research at Harvard and has overseen the revitalization of the University’s libraries and many of its museums and cultural institutions, plans to leave his post after nearly a decade.