Tag: Stem Cells
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Nation & World
Breakthrough within reach for diabetes scientist and patients nearest to his heart
One hundred years after the discovery of insulin, replacement therapy represents “a new kind of medicine,” says Douglas Melton, co-director of Harvard Stem Cell Institute.
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Nation & World
Cultivating a career in science
It was her interest in research that brought Zahra Aldawood, D.M.Sc. ’18, M.M.Sc. ’21, to Harvard School of Dental Medicine.
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Nation & World
Big step forward for planned center to boost cell- and gene-therapy advances
A new cell manufacturing and innovation center, headed by a unique partnership between academia and industry, has taken a key step — signing a lease in Watertown for its new home — as it looks toward 2022 opening.
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Nation & World
Getting to the bottom of goosebumps
Researchers have found that the same cell types that cause goosebumps are responsible for controlling hair growth.
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Nation & World
Breakthrough to halt premature aging of cells
Potential drug treatments are being developed for telomere diseases, in which cells age prematurely.
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Nation & World
Feel like kids, spouse, work giving you gray hair? They may be
Harvard scientists have found evidence to support long-standing anecdotes that stress turns hair gray.
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Nation & World
A solid vaccine for liquid tumors
A new study presents an alternative treatment for acute myeloid leukemia (AML) that has the potential to eliminate AML cells completely.
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Nation & World
Study looks to genome editing to treat deadly degenerative disorder
Harvard stem-cell research receives support from Sarepta Therapeutics for work on Duchenne muscular dystrophy.
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Nation & World
Backbone of success
Harvard researchers have unveiled the first stem cell models of human spine development, setting the stage for better understanding of musculoskeletal and metabolic disorders, including congenital scoliosis, muscular dystrophy, and Type 2 diabetes.
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Nation & World
Still wrestling with big questions
Harvard biochemistry professor Jack Strominger is still working in his lab at 94 years old. He will retire and become emeritus in July.
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Nation & World
A SWIFTer way to build organs
A new technique called SWIFT (sacrificial writing into functional tissue) ultimately may be used therapeutically to repair and replace human organs with lab-grown versions containing patients’ own cells.
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Nation & World
Speeding up single-cell genomics research
Harvard researchers have devised a time-saving method that makes it possible to speed up the process of profiling gene regulation in tens of thousands of individual human cells in a single day, a development that promises to boost genomics research.
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Nation & World
Toward safer bone-marrow transplants
The combination of the antibody CD117 and the drug saporin selectively targets blood stem cells, making transplantation safer by limiting collateral damage caused by the current standard of treatment, chemotherapy, and radiation.
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Nation & World
Epidemic of autoimmune diseases calls for action
Scientists at the Harvard Stem Cell Institute are seeking ways to protect newly transplanted cells from autoimmune attack.
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Nation & World
Rewinding the brain
Professor of Stem Cell and Regenerative Biology Paola Arlotta is seeking to develop a new tool to understanding brain function and dysfunction: self-generating brain organoids.
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Nation & World
Professor Paola Arlotta awarded George Ledlie Prize
Developmental neurobiologist Paola Arlotta has been awarded the George Ledlie Prize by the President and Fellows of Harvard College.
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Nation & World
Closing in on a breakthrough
New findings from the lab of Harvard Medical School Dean George Daley suggest a path for creating immune-matched blood cells, derived from patients’ own cells, for treatment purposes.
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Nation & World
New vista for brain disorder research
For the first time, researchers describe the types of cells generated in brain organoids, networks of nerve cells, and show the greater diversity, complexity, and response to stimulation developed for nine months and longer.
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Nation & World
How old can we get? It might be written in stem cells
No clock, no crystal ball, but lots of excitement — and ambition — among Harvard scientists
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Nation & World
Progress in treating hearing loss
Harvard Stem Cell Institute researchers have developed a drug cocktail that unlocks the potential to regrow inner-ear hair cells, which could help combat hearing loss.
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Nation & World
Colorful clones track stem cells
Harvard Stem Cell Institute researchers have used a colorful cell-labeling technique to track the development of the blood system and trace the lineage of an adult blood cell traveling through the vast networks of veins, arteries, and capillaries back to its parent stem cell in the marrow.
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Nation & World
Medical hope on horizon
Stem cell science is accelerating development of therapies for diabetes, ALS, other diseases, researchers tell HUBweek sessions.
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Nation & World
Douglas Melton wins Ogawa-Yamanaka Stem Cell Prize
Douglas Melton, co-director of Harvard Stem Cell Institute and the Xander University Professor in Harvard’s Department of Stem Cell and Regenerative Biology, has been awarded the 2016 Ogawa-Yamanaka Stem Cell Prize from the Gladstone Institutes.
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Nation & World
Gene therapy for sickle cell disease passes key preclinical test
A precision-engineered gene therapy virus, inserted into blood stem cells that are then transplanted, markedly reduced sickle-induced red-cell damage in mice with sickle cell disease, researchers from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center reported in the Journal of Clinical Investigation.
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Nation & World
New drug target for Rett syndrome
Rett syndrome is a relatively common neurodevelopmental disorder, the second most common cause of intellectual disability in girls after Down syndrome. Building on 2004 findings, Harvard researchers identified a faulty signaling pathway that, when corrected in mice, improves the symptoms of Rett syndrome.
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Nation & World
Red blood cell production increases, but cost goes down
New research suggests a way to cost-effectively manufacture red blood cells from stem cells; the patients who could potentially benefit include those who cannot use blood currently available in blood banks.
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Nation & World
Converting skin cells to stem cells creates ‘kidney structures’
Researchers create complex kidney structures from human stem cells derived from the skin of adult patients.
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Nation & World
Filling a void in stem cell therapy
New porous hydrogel could boost success of some stem cell-based tissue regeneration, researchers say.
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Nation & World
Zebrafish reveal drugs that may improve bone marrow transplant
Using large-scale zebrafish drug-screening models, Harvard Stem Cell Institute researchers at Boston Children’s Hospital have identified a potent group of chemicals that helps bone marrow transplants engraft, or “take.”