Featured series 
Tag: Tumors
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Nation & World
Mapping the cancer connection
A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.
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Nation & World
Targeted drug shows promise in advanced kidney cancer
Harvard researchers at Dana-Farber Cancer Institute have developed a novel targeted drug that shows promise in advanced kidney cancer by interfering with the abnormal blood vessel formation that fuels tumor growth.
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Nation & World
Exposing how pancreatic cancer does its dirty work
New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.
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Nation & World
Platelet ‘decoys’ outsmart both clots and cancer
A team of researchers at the Wyss Institute at Harvard University and several collaborating institutions has created a drug-free, reversible antiplatelet therapy that uses deactivated “decoy” platelets to reduce the risk of blood clots and potentially prevent cancer metastasis.
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Nation & World
Personal cancer vaccines show promise
Researchers have found that an injectable scaffold that incorporates tumor-specific peptides can be personalized, stimulating a patient’s immune system to destroy his or her unique cancer tumors.
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Nation & World
Spread of multiple myeloma halted in mice
In an advance against cancer metastasis, scientists at the Harvard-affiliated Dana-Farber Cancer Institute have shown that a specially developed compound can impede multiple myeloma in mice from spreading to the bones.
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Nation & World
Aspirin’s impact on colorectal cancer
Harvard researchers at Dana-Farber Cancer Institute find that aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but it has no effect on patients who lack the mutation.
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Nation & World
Size matters in drug delivery
A new study led by researchers at the Harvard School of Engineering and Applied Sciences and Massachusetts General Hospital has found that normalizing blood vessels within tumors, which improves the delivery of standard chemotherapy drugs, can actually block the delivery of larger nanotherapy molecules.
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Nation & World
Cancer stem cells made, not born
In cancer, tumors aren’t uniform: they are more like complex societies, each with a unique balance of cancer cell types playing different roles. Understanding this “social structure” of tumors is critical for treatment decisions in the clinic because different cell types may be sensitive to different drugs.
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Nation & World
Increasing odds for survival
A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and is potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Harvard investigators at the Dana-Farber Cancer Institute.
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Nation & World
What’s behind aggressive breast cancer
Harvard scientists at Dana-Farber Cancer Institute have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.
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Nation & World
Cancer vaccine success
A cancer vaccine carried into the body on a carefully engineered, fingernail-sized implant is the first to successfully eliminate tumors in mammals, scientists report this week (Nov. 25) in the journal Science Translational Medicine.
