Featured series 
Tag: Lee Rubin
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Health
How old can we get? It might be written in stem cells
No clock, no crystal ball, but lots of excitement — and ambition — among Harvard scientists
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Health
Compound protects nerve cells targeted by diseases
Harvard researchers have identified a compound that helps protect the cells destroyed by spinal muscular atrophy, the most frequent fatal genetic disease of young children.
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Health
Hope against disease targeting children
Harvard Stem Cell Institute researchers studying spinal muscular atrophy have found molecular changes that help trigger the genetic disease in children.
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Health
Vital genes in fat production found
Scientists at Harvard Stem Cell Institute have found a way to both make more energy-burning human brown fat cells and make the cells themselves more active, a discovery that could have therapeutic potential for diabetes, obesity, and other metabolic diseases.
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Health
Creating pain-sensing neurons
Harvard Stem Cell Institute researchers at Boston Children’s Hospital and Harvard’s Department of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain-sensing neurons that respond to a number of stimuli that cause acute and inflammatory distress.
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Health
A decade of breakthroughs
The Harvard Stem Cell Institute is now 10 years old. What began as an idea embracing cross-disciplinary research quickly became a generator of scientific discoveries.
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Health
Hope for aging brains, skeletal muscle
Researchers at the Harvard Stem Cell Institute have shown that a protein, one they previously demonstrated can make failing hearts in aging mice appear more like those of young and healthy mice, similarly improves brain and skeletal muscle function in aging mice.
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Health
Developing cancer drugs
Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.
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Health
Big boost in drug discovery
Using a new, stem cell-based, drug-screening technology that could reinvent and greatly reduce the cost of developing pharmaceuticals, researchers at the Harvard Stem Cell Institute have found a compound that is more effective in protecting the neurons killed in amyotrophic lateral sclerosis than are two drugs that failed in human clinical trials.
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Health
Personalized medicine closer to reality
A consortium of scientists at 20 institutions, led by a principal faculty member at the Harvard Stem Cell Institute, has used stem cells to take a major step toward developing personalized medicine to treat Parkinson’s disease.
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Campus & Community
Learning about research
Nearly 150 Harvard undergraduates spent 10 weeks last summer learning the nuts and bolts of academic research — from ethnography to techniques for culturing living tissue — with faculty in three immersive programs.
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Health
Harvard team reports major step forward in cell reprogramming
A team of Harvard Stem Cell Institute (HSCI) researchers has made a major advance toward producing induced pluripotent stem cells, or iPS cells, that are safe enough to use in treating diseases in patients. “This demonstrates that we’re halfway home, and remarkably we got halfway home with just one chemical,” said Kevin Eggan, an HSCI…
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Health
GlaxoSmithKline and Harvard Stem Cell Institute announce major collaboration agreement
GlaxoSmithKline (GSK) and the Harvard Stem Cell Institute (HSCI) today announced that they have entered into a five-year, $25 million-plus collaborative agreement to build a unique alliance in stem cell science to hasten the development of treatments and cures for a range of diseases. GSK’s investment, one of the largest by a pharmaceutical company in…