Street smarts
HarvardScience
By: Caroline Perry/
February 9, 2012
Secrets of ancient Chinese remedy revealed
For roughly 2,000 years, Chinese herbalists have treated malaria using a root extract, commonly known as chang shan, from a type of hydrangea that grows in Tibet and Nepal. More recent studies suggest that halofuginone, a compound derived from this extract’s bioactive ingredient, could be used to treat many autoimmune disorders as well. Now, researchers from the Harvard School of Dental Medicine have discovered the molecular secrets behind this herbal extract’s power.
Trouble afloat: Ocean plastics
Plastic pollution in the oceans is a large and growing problem, but one that may be out of the reach of consumers to solve and instead may require cooperation from industry, said Max Liboiron, regional co-director of the Plastic Pollution Coalition.
A swimsuit like shark skin? Not so fast
Experiments conducted in a Harvard lab reveal that, while sharks’ sandpaperlike skin does allow the animals to swim faster and more efficiently, the structure of some high-tech swimsuits has no effect when it comes to reducing drag as swimmers move through the water.
Exploring roots of hunger, eating behaviors
Synaptic plasticity — the ability of the synaptic connections between the brain’s neurons to change and modify over time — has been shown to be a key to memory formation and the acquisition of new learning behaviors. Now research reveals that the neural circuits controlling hunger and eating behaviors are also controlled by plasticity.
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Researchers in a Harvard lab have developed a device, dubbed LADY GAGA, that allows them for the first time to precisely control airborne scents. They have used the device in their work unraveling how animals make navigational decisions based on their environment.
Right time for ‘end-of-life’ talk
A study by Harvard-affiliated Dana-Farber Cancer Institute finds that most terminally ill cancer patients discuss end-of-life care with physicians but that such discussions often occur late in their illness.
For cutting-edge biomedical materials, try corn
One might expect, these days, to find corn products in food, fuel, and fabric, but a corn-based glue that can heal an injured eyeball? That's a-maize-ing.
The search for life’s stirrings
As science wrestles with the problem of how life arose on Earth, hindsight shows that seemingly intractable obstacles can have simple, even elegant solutions, said Nobel laureate Jack Szostak.
Biophysicist Aravinthan Samuel has developed new techniques to monitor and influence the behavior of roundworms to learn how their basic nervous systems work, a first step to understanding the circuitry in more complex creatures, like humans.
As strong as an insect’s shell
Wyss Institute scientists have created a material that mimics the hard outer skin of bugs. The result is low-cost and easily manufactured, and tough. It eventually might provide a more environmentally friendly alternative to plastic.
The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool.
Triumphs against smallpox, polio, AIDS
Harvard researchers have been at the forefront of many battles against devastating diseases, leading pivotal breakthroughs against scourges from 1800 to the present.
Decoding keys to a healthy life
Now 74 years young, the Harvard Study of Adult Development continues to yield a treasure trove of data about how people behave, and change — including predictions of strong indicators to a happy life.
Designing in the human context
For a week in January, 40 students from a variety of backgrounds — comparative literature to computer science — engaged in a “design thinking” workshop led by IDEO, an internationally renowned design consulting firm. Throughout, the human element was key — How do people actually use a product? — as was a certain amount of ad-libbed fun.
The ‘diversity problem’ in science
Opportunities for women and people of color to pursue careers in science have improved in recent years, but still lag behind those of white men, Harvard College Dean Evelynn M. Hammonds told a crowd at the Massachusetts Institute of Technology in her keynote address at the Institute Diversity Summit.
In 1934, a group of enterprising young Turks pooled their money and bought construction plans for a glider. Pioneers in the infancy of aviation, they built it by hand, out of wood and fabric, and when the time came for its maiden flight, they drew straws.
Early-stage venture fund launches
Today, the Experiment Fund, a new seed-stage investment fund, opens its doors with backing from storied venture capital firm New Enterprise Associates (NEA). Designed specifically to support student start-ups and nurture novel technologies and platforms created in Cambridge (or by innovators educated in Cambridge), the Experiment Fund will eventually include additional strategic angel investors and advisers.
Broad Institute awarded $32.5M grant
The Eli and Edythe L. Broad Institute of Harvard and MIT today announced that it has received a $32.5 million grant from the Boston-based Klarman Family Foundation to support a new collaborative effort focused on deciphering how human cells are wired.
PFCs may hinder vaccine response
Perfluorinated compounds (PFCs), widely used in manufactured products such as non-stick cookware, waterproof clothing, and fast-food packaging, were associated with lowered immune response to vaccinations in children in research led by Philippe Grandjean of the Harvard School of Public Health.
With a little help from our ancient friends
The social networks of the Hadza, a group of hunter-gatherers in Tanzania, show evidence that many elements of social network structure may have been present at an early point in human history.
New research at Harvard explains how bacterial biofilms expand on teeth, pipes, surgical instruments, and crops.
Dozens of Harvard undergraduates started the year with a new emphasis on wellness, thanks to the Optimal Health program. With presentations from a lifestyle medicine consultant, a nutritionist, a personal trainer, a sleep specialist, and a stress manager, Optimal Health emphasized prevention and fitness.
Color-coded food labeling and adjusting the way food items are positioned in display cases encouraged healthy choices in a large hospital cafeteria in a study by MGH researchers.
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