Featured series 
Tag: Stuart Orkin
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Health
Prospect of shorter treatment and cure for chronic myelogenous leukemia
Chronic myelogenous leukemia (CML) is a slowly progressing type of blood cancer that develops in the bone marrow. Researchers discovered that CML stem cells die in response to inhibition of a protein called Ezh2. Drugs that target the protein are currently being tested in clinical trials for other cancers.
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Health
Finally, hope for a young patient
A gene therapy trial points to a healthier future for a young patient suffering from a rare immune disease.
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Health
New hope in regenerative medicine
Harvard Stem Cell Institute researchers at Boston Children’s Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells have the functional hallmarks of HSCs and are able to self-renew like those cells.
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Health
Dialing down sickle cell disease
Flipping a single molecular switch can reverse illness in an animal model of sickle cell disease, according to a study by Harvard researchers at Children’s Hospital Boston and Dana-Farber Cancer Institute.
