Tag: CRISPR
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Science & Tech
2 very different microbes immune to the same viruses? Scientists were puzzled.
Genomic analysis suggests host diversity is far greater than previously thought.
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Science & Tech
Taking a step toward discovering the cause of joint disease
A Harvard study could lead to potential therapeutics for one of the most prominent ailments of the elderly and one of the most prominent musculoskeletal defects in newborns.
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Science & Tech
Face mask can help diagnose COVID-19
A team of researchers from the Wyss Institute has found a way to embed synthetic biology reactions into fabrics, creating wearable biosensors that can be customized to detect pathogens and toxins and alert the wearer.
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Science & Tech
Innovative tool offers hope for children with rapid-aging disease
Several hundred children worldwide live with progeria, a deadly premature aging disease.
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Science & Tech
A promise to a friend
Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.
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Science & Tech
Capabilities of CRISPR gene editing expanded
Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.
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Science & Tech
A crisper CRISPR
Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.
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Health
Power and pitfalls of gene editing
CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.
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Science & Tech
Forward thinking
Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.
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Science & Tech
Learning why cancer drugs work (or don’t)
Assistant Professor Brian Liau of the Chemistry and Chemical Biology Department has answered the question of why some new drugs for acute myeloid leukemia don’t work by combining CRISPR gene editing with small-molecule inhibitor treatments in a technique he calls CRISPR-suppressor scanning.
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Science & Tech
Researchers ID molecules that rein in CRISPR systems
Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.
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Health
Pig organs for human patients: A challenge fit for CRISPR
To help develop safe and effective cells, tissues, and organs for medical transplant into human patients, Harvard’s Office of Technology Development has granted a technology license to the Cambridge biotech startup eGenesis.
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Science & Tech
CRISPR’s breakthrough implications
CRISPR pioneer Jennifer Doudna discussed the gene-editing technology’s rapid spread and the need for a robust discussion about the ethics of its applications.
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Health
Seeing promise, and limits, in embryo edit
The disease-targeting embryo edit at Oregon Health & Science University signals a path for “those rare situations where the genes really are life-threatening,” says Harvard bioethicist Robert Truog.
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Science & Tech
New CRISPR technology takes cells to the movies
CRISPR system-based technology enables the chronological recording of digital information, turning living cells into a biological hard drive that can record information.
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Health
Red blood cell production increases, but cost goes down
New research suggests a way to cost-effectively manufacture red blood cells from stem cells; the patients who could potentially benefit include those who cannot use blood currently available in blood banks.
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Health
Improved accuracy in genome editing
A team of scientists has engineered a form of the genome-editing protein Cas9 that can be controlled by a small molecule and offers improved DNA specificity.
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Health
A promising strategy against HIV
Harvard Stem Cell Institute researchers at Massachusetts General and Boston Children’s hospitals for the first time have used a relatively new gene-editing technique to create what could prove to be an effective technique for blocking HIV from invading and destroying patients’ immune systems.