Tag: Alzheimer’s
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Nation & World
Human brain seems impossible to map. What if we started with mice?
Harvard-led project seeks to create the first comprehensive diagram of every neural connection.
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Nation & World
Has first person to live to be 150 been born?
Harvard researchers reported that they can age and then restore youth to lab mice, using a gene cocktail that has already restored vision in mice.
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Nation & World
Can Amazon remake health care?
Health policy expert explains Amazon’s nearly $4 billion investment in One Medical and what the marketplace disruptor can, and cannot, do to change the way consumers get their health care.
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Nation & World
Hallmarks of Alzheimer’s found well before diagnosis
A new study shows the impact of early amyloid-β and tau protein accumulation on disrupting brain connections important for memory. These disrupted connections were present even before signs of cognitive impairment were observed.
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Nation & World
Researchers identify signaling molecule that may help prevent Alzheimer’s
New research in humans and mice identifies a particular signaling molecule that can help modify inflammation and the immune system to protect against Alzheimer’s disease.
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Nation & World
Dissecting the ‘undruggable’
Researchers at Harvard have designed new, highly selective tools that can add or remove sugars from a protein with no off-target effects, to examine exactly what the sugars are doing and engineer them into new treatments for “undruggable” proteins.
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Nation & World
How older adults may be doubling their risk of dementia
A new survey found that getting five or fewer hours of sleep in the older adult population was associated with double the risk of dementia.
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Nation & World
Tracking the proteins before Alzheimer’s takes hold
A team led by investigators has now developed an automated method that can identify and track the development of two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer’s disease.
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Nation & World
How a doctor learned to become a caregiver
Harvard Professor Arthur Kleinman’s wife, Joan, began to struggle with a rare form of early Alzheimer’s disease at 59.
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Nation & World
Scientists pinpoint neural activity’s role in human longevity
The brain’s neural activity, long implicated in disorders ranging from dementia to epilepsy, also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute.
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Nation & World
Seeing brain activity in ‘almost real time’
Researchers from Brigham and Women’s Hospital, King’s College London, and other institutions have developed a technique for measuring brain activity that’s 60 times faster than traditional fMRI.
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Nation & World
Exercise, fasting help cells shed defective proteins
A new study from the Blavatnik Institute finds that intense exercise and fasting activate hormones that boost cells’ capacity to dispose of defective proteins, which clog up the cell, interfere with its functions, and, over time, precipitate diseases including neurodegenerative conditions such as ALS and Alzheimer’s.
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Nation & World
Probing the sleep-deprived brain
Nora D. Volkow, director of the National Institute on Drug Abuse, spoke at Radcliffe on the harmful effects of sleep deprivation.
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Nation & World
Alzheimer’s insights in single cells
A study of plaque production at single-cell level holds promise to help improve Alzheimer’s treatment.
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Nation & World
Neurons reprogrammed in animals
Harvard Stem Cell Institute researchers have shown that the networks of communication among reprogrammed neurons and their neighbors in the brains of living animals can also be changed, or “rewired.”
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Nation & World
‘New clarity’ against Alzheimer’s
Rudolph Tanzi of Harvard Medical School, recently named to Time’s list of the most influential people in the world, talks about the promising future of Alzheimer’s research.
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Nation & World
A new understanding of Alzheimer’s
Using the principle of natural selection, researchers have outlined a new model of the disease suggesting that mitochondria — power plants for cells — might be at its center.
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Nation & World
Fixing the way we fix the brain
With neurodegenerative diseases affecting millions and having the potential to bankrupt the U.S. health care system, Harvard Medical School, seven pharmaceutical companies, and the Massachusetts state government have formed the Massachusetts Neuroscience Consortium. The goal: to offer new collaborative research models.
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Nation & World
Finding the start of Alzheimer’s disease
Faces are hard to remember. Even harder are the names that go with them. It’s one of the most common problems people face as they get older.
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Nation & World
MIND recognizes Cure Alzheimer’s Fund with first philanthropic award
Established in 2001 by members of the Harvard Medical School faculty, the MassGeneral Institute for Neurodegenerative Disease (MIND) recently recognized the Cure Alzheimer’s Fund with its first Philanthropic Innovation and Investment Award. The award recognizes donors who have made substantial commitments to visionary work that cannot be funded through other sources but has the potential…