Featured series 
Tag: Neurodegenerative disease
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Nation & World
Blocking tau may help ALS patients
Mass. General study uncovers potential new treatment strategy for disease.
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Nation & World
Dissecting the ‘undruggable’
Researchers at Harvard have designed new, highly selective tools that can add or remove sugars from a protein with no off-target effects, to examine exactly what the sugars are doing and engineer them into new treatments for “undruggable” proteins.
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Nation & World
Compound protects nerve cells targeted by diseases
Harvard researchers have identified a compound that helps protect the cells destroyed by spinal muscular atrophy, the most frequent fatal genetic disease of young children.
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Nation & World
Giving Huntington’s disease the one-two punch
The identification of a molecular compound that combats Huntington’s disease by means of two separate mechanisms may be the watershed moment in the battle against neurodegenerative diseases.
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Nation & World
Hope against disease targeting children
Harvard Stem Cell Institute researchers studying spinal muscular atrophy have found molecular changes that help trigger the genetic disease in children.
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Nation & World
Injectable device delivers nano-view of the brain
An international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons.
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Nation & World
New avenue in neurobiology
Harvard stem cell biologists have proven that it is possible to turn one type of already differentiated neuron into another inside the brain, and their findings may have enormous implications for the treatment of neurodegenerative diseases.
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Nation & World
Fixing the way we fix the brain
With neurodegenerative diseases affecting millions and having the potential to bankrupt the U.S. health care system, Harvard Medical School, seven pharmaceutical companies, and the Massachusetts state government have formed the Massachusetts Neuroscience Consortium. The goal: to offer new collaborative research models.
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Nation & World
Slowing ALS symptom progression
Harvard researchers find that treatment with dexpramipexole — a novel drug believed to prevent dysfunction of mitochondria, the subcellular structures that provide most of a cell’s energy — appears to slow symptom progression in the neurodegenerative disease amyotrophic lateral sclerosis (ALS).
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Nation & World
A new target for Parkinson’s therapy
In a new finding from Harvard-affiliated Brigham and Women’s Hospital (BWH), researchers identify a link between Parkinson’s disease onset and dysfunctional activity of energy genes in the brain and identify a potential therapeutic target to reverse this energy gene failure.
