Featured series 
Tag: HSCI
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Health
Personalized medicine closer to reality
A consortium of scientists at 20 institutions, led by a principal faculty member at the Harvard Stem Cell Institute, has used stem cells to take a major step toward developing personalized medicine to treat Parkinson’s disease.
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Health
Big advance against cystic fibrosis
Harvard stem cell researchers at Massachusetts General Hospital have taken a critical step toward discovering in the relatively near future a drug to control cystic fibrosis, a fatal lung disease that claims about 500 lives each year, with 1,000 new cases diagnosed annually.
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Health
Age-related effects of MS may prove reversible
In a new study, Harvard stem cell researchers and scientists at the University of Cambridge have found that the age-related degeneration in conditions such as multiple sclerosis (MS) may be reversible.
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Health
Stem cell lessons
Five years after first gaining institutional permission to attempt to produce stem cell lines via somatic cell nuclear transfer (SCNT), two Harvard researchers and a former Harvard postdoctoral fellow have closed the loop with a flurry of new studies and a commentary in several leading journals.
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Health
From skin cells to motor neurons
Harvard stem cell researchers have succeeded in reprogramming adult mouse skin cells directly into the type of motor neurons damaged in amyotrophic lateral sclerosis, best known as Lou Gehrig’s disease, and spinal muscular atrophy.
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Health
Helping the heart help itself
Stem cells being transfused into post-heart attack patients may not be developing into new heart muscle, but they still appear to be beneficial. Some stem cells in the bone marrow, called c-kit+ cells, appear capable of stimulating adult stem cells already present in the heart to repair damaged tissue.
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Health
Two studies prove value of iPS cells
A team of Harvard Stem Cell Institute (HSCI) researchers, in collaboration with scientists at Columbia University, have demonstrated that many iPS cells (stem cells created by reprogramming adult cells) are the equal of human embryonic stem cells in creating human motor neurons, the cells destroyed in a number of neurological diseases, including Parkinson’s.
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Health
Concentrating on stem cells
New concentration is the latest example of the University’s commitment to and pre-eminence in the promising field of stem cell research.
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Campus & Community
A Stem Cell Discovery Could Help Diabetics
This week, scientists at the Harvard Stem Cell Institute (HSCI) reported the first success in generating new populations of insulin-producing cells using skin cells of type 1 diabetes patients.
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Health
Safer stem cells for therapy
When stem cell researchers in Japan and the United States announced in 2007 that they had developed long-sought methods to return fully developed adult human cells to an embryonic-like state, the world of stem cell research was turned upside down.
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Campus & Community
2008-09: A look back
As Commencement closes another chapter of the Harvard story, here is a brief backward glance at highlights of the year that was.
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Science & Tech
Embryo’s heartbeat drives blood stem cell formation
Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood. Two groups of Harvard Stem Cell Institute (HSCI) researchers from Children’s Hospital Boston (Children’s) and Brigham and Women’s Hospital (BWH) — presenting multiple lines of evidence from zebrafish, mice, and mouse embryonic stem…
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Health
Skin biology illuminates how stem cells operate
As a girl, Elaine Fuchs borrowed her mother’s old strainers and mixing bowls to collect polliwogs, an activity she credits for her present-day career as a biologist.
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Health
Five named Early Career Scientists
Five Harvard researchers are among 50 young scientists nationwide who will have their work supported for the next six years by a new initiative from the Howard Hughes Medical Institute (HHMI).
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Health
How stem cells find their way around
Harvard Stem Cell Institute (HSCI) researchers have for the first time identified in mice a cellular mechanism that directs stem cells to their ultimate destination in the body.
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Health
Science programs advancing
Harvard President Drew Faust today renewed the University’s commitment to the vision of advancing interdisciplinary, collaborative science in general, and the Department of Stem Cell and Regenerative Biology (SCRB), the Harvard Stem Cell Institute (HSCI), and the Wyss Institute for Biologically Inspired Engineering (WIBIE) in particular.
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Campus & Community
Eggan recognized by president
Harvard Stem Cell Institute (HSCI) scientist Kevin Eggan was cited by President George W. Bush for his work in advancing the field of stem cell science on both scientific and educational levels.
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Health
Researchers replicate ALS process in lab dish
A Harvard Stem Cell Institute (HSCI) research team has succeeded in deriving spinal motor neurons from human embryonic stem cells, and has then used them to replicate the Amyotrophic Lateral Sclerosis (ALS) disease process in a laboratory dish.
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Health
Researchers successfully track voyage of single stem cell
The title of the letter in the Dec. 3 edition of the journal Nature — “Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche” — doesn’t begin to describe it, this real-life, real-time view of a single stem cell making its way to its ultimate home inside the bone-marrow cavity of a living mouse.
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Health
Major step forward in cell reprogramming
Imagine, if you can, a day within the next decade when a physician-scientist could remove a skin cell from your arm and with a few chemicals turn that fully formed adult cell into a dish of stem cells genetically matched to you.
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Science & Tech
HSCI creates Web presence for research
The Harvard Stem Cell Institute (HSCI) and the Harvard Initiative in Innovative Computing (IIC) have launched an online stem cell textbook that seeks to engage and inform the stem cell community as it presents up-to-date stem cell science in a format useful to scientists and students.
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Health
Advance in pluripotent cell creation
A team of Harvard Stem Cell Institute (HSCI) scientists has taken an important step toward producing induced pluripotent stem (iPS) cells that are safe to transplant into patients to treat diseases. Excitement over the ability of researchers to create this form of stem cell by inserting four genes into adult cells has thus far been…
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Health
HSCI researchers see major breakthrough
In a feat of biological prestidigitation likely to turn the field of regenerative medicine on its head, Harvard Stem Cell Institute (HSCI) co-director Doug Melton and postdoctoral fellow Qiao “Joe” Zhou report having achieved what has long been a dream and ultimate goal of developmental biologists — directly turning a fully formed adult cell into…
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Health
Harvard faculty members discuss state of research
A panel of experts said Tuesday (March 11) that stem cell research’s biggest impact on patients’ health likely won’t come from therapies that inject stem cells or implant tissues made from them, but rather from the knowledge gained by examining diseased tissues grown from the cells.
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Health
From adult to embryonic stem cell
Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like state without the use of viruses or cancer-causing genes.
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Campus & Community
HMS Dean Flier hails new, cooperative era in Harvard science
Harvard Medical School Dean Jeffrey Flier said Friday (Nov. 2) that new approaches are needed to advance the fight against disease and embraced cross-institutional collaborations at Harvard as a way to bring new thinking to old problems.
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Health
Panel investigates media reporting on science and politics of stem cells
Stem cells, politics, “fairness,” and what one participant termed “the disintegration of traditional journalism,” were all on the bill at Thursday night’s (Oct. 18) public forum titled “Stem Cells and the Media,” hosted by the Harvard Stem Cell Institute.
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Health
Stem Cell Summit draws 500 participants
Massachusetts Gov. Deval Patrick Wed-nesday (Oct. 3) called on those attending the second day of a Harvard Stem Cell Institute (HSCI)-sponsored Stem Cell Summit to support his proposed $1 billion life sciences initiative “so we can get partnering with you.”
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Health
Major progress toward cell reprogramming; researchers approach key goal of biologists
Two Harvard Stem Cell Institute (HSCI) researchers and scientists at Whitehead Institute and Japan’s Kyoto University have independently taken major steps toward discovering ways to reprogram cells in order to direct their development – a key goal in developmental biology and regenerative medicine.