Featured series 
Tag: Leonard Zon
-
Nation & World
How mutant protein leads to melanoma
Discovery of new mechanism could have wide implications for other cancers.
-
Nation & World
Three Medical School faculty elected to NAS
Three Harvard Medical School scientists are among the 150 individuals recently elected to the National Academy of Sciences in recognition of their distinguished and continuing achievements in original research.
-
Nation & World
Not so black and white
Harvard researchers identify a mechanism with therapeutic potential for anemia.
-
Nation & World
Through the lens of black health
Tania Fabo’s ambition is to bridge the gap between biomedical research in the laboratory and public health efforts to reduce health inequalities among minorities.
-
Nation & World
Colorful clones track stem cells
Harvard Stem Cell Institute researchers have used a colorful cell-labeling technique to track the development of the blood system and trace the lineage of an adult blood cell traveling through the vast networks of veins, arteries, and capillaries back to its parent stem cell in the marrow.
-
Nation & World
A cancer’s surprise origins, caught in action
Researchers have found that cancer begins after activation of an oncogene or loss of a tumor suppressor, and involves a change that takes a single cell back to a stem cell state. They believe this model may apply not only to melanoma, but to most if not all cancers.
-
Nation & World
Zebrafish reveal drugs that may improve bone marrow transplant
Using large-scale zebrafish drug-screening models, Harvard Stem Cell Institute researchers at Boston Children’s Hospital have identified a potent group of chemicals that helps bone marrow transplants engraft, or “take.”
-
Nation & World
Imaging captures how blood stem cells take root
Harvard-affiliated researchers have provided a see-through zebrafish and enhanced imaging that offer the first direct glimpse of how blood stem cells take root in the body to generate blood.
-
Nation & World
Clues on generating muscles
Harvard stem cell scientists have discovered that the same chemicals that stimulate muscle development in zebrafish can be used to differentiate human stem cells into muscle cells in the laboratory, which makes muscle cell therapy a more realistic clinical possibility.
-
Nation & World
Improving cord blood transplants
They began with a discovery in zebrafish in 2007, and now researchers at the Harvard Stem Cell Institute (HSCI) have published initial results of a Phase Ib human clinical trial of a therapeutic that could improve the success of blood stem cell transplantation. This marks the first time that HSCI has carried a discovery from…
-
Nation & World
Better blood
An innovative experimental treatment for boosting the effectiveness of blood stem-cell transplants with umbilical cord blood has a favorable safety profile in long-term animal studies, according to Harvard Stem Cell Institute scientists at Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, and Children’s Hospital Boston.
-
Nation & World
Progress against melanoma
Harvard stem cell researchers at Children’s Hospital Boston have taken two important steps toward development of a new way of treating melanoma, the most virulent form of skin cancer.
-
Nation & World
Zon, Scadden recognized by American Society of Hematology
Two Harvard faculty members and members of the Harvard Stem Cell Institute, David Scadden and Leonard Zon, have won awards from the American Society of Hematology for contributions to understanding and treating blood diseases.
-
Nation & World
Scadden, Zon win Hematology Society awards
Two Harvard professors will receive awards from the American Society of Hematology for their “significant contributions to the understanding and treatment of hematologic diseases.” David Scadden, who is co-director of the…
-
Nation & World
Three Harvard teams to receive $9 million each in federal funding for stem cell research
Three teams of Harvard Stem Cell Institute (HSCI) researchers are slated to receive $27 million over seven years in National Heart Lung and Blood Institute (NHLBI) grants for the development…
-
Nation & World
Mechanism directing stem cells to their destination identified;
Harvard Stem Cell Institute (HSCI) researchers have for the first time identified in mice a cellular mechanism that directs stem cells to their ultimate destination in the body. The finding…
-
Nation & World
A new look at anemia
Leonard Zon and his colleagues at the Harvard Medical School were trying to find out how hemoglobin forms by studying zebrafish, small piscians whose transparent bodies allow their inner workings…
-
Nation & World
Stem cell science
“Stem-cell transplants are already performed every day in Harvard-affiliated hospitals — and around the world,” says Harvard Stem Cell Initiative codirector David Scadden, professor of medicine at Harvard Medical School…