Featured series 
Tag: Cancer
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Campus & Community
Does Infection Boost Prostate Cancer Risk?
In the new study, Jennifer Stark of the Harvard School of Public Health in Boston and colleagues analyzed blood samples from 673 men with prostate cancer who participated in the Physicians’ Health Study, a large, ongoing study examining a variety of health issues.
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Health
New metabolic safeguards against tumor cells revealed
Cells don’t like to be alone. In the early stages of tumor formation, a cell might be pushed out of its normal home environment due to excessive growth. But a cell normally responds to this homeless state by dismantling its nucleus, packing up its DNA, and offering itself to be eaten by immune system cells.…
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Health
Study supports DNA repair-blocker research in cancer therapy
Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells’ DNA with potent drugs while simultaneously preventing the cells from repairing themselves. The findings, reported in the Aug. 14 edition of Molecular Cell, help explain the promising results being seen in clinical trials of compounds…
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Health
Researchers discover chemical that kills cancer stem cells
A multi-institutional team of Boston-area researchers has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors. These cells, known as cancer stem cells, are thought to enable cancers to spread — and to reemerge after seemingly successful treatment. Although…
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Health
Postdiagnosis aspirin use reduces risk of dying from colorectal cancer
Regular use of aspirin after colorectal cancer diagnosis may reduce the risk of cancer death, report Harvard researchers at Massachusetts General Hospital (MGH), Dana-Farber Cancer Institute (DFCI) and Brigham and Women’s Hospital. In today’s edition of the Journal of the American Medical Association, the study’s authors also find that the aspirin-associated survival advantage was seen…
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Health
An unusual collection: A brain tumor tissue bank
Five years ago, as she was walking into Caritas Holy Family Hospital and Medical Center in Methuen, Mass., Patricia Fay saw a priest she knew and cornered him. “I’m like ‘Oh, Father Peter! And I sort of grabbed him by his arm,” she recounts.“I said, ‘What are you doing here? Father Peter! I could use…
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Health
Damon Runyon Cancer Research Foundation awards fellowships to Harvard scientists
The Damon Runyon Cancer Research Foundation, a nonprofit organization focused on supporting exceptional early career researchers and innovative cancer research, has selected four Harvard affiliates to receive Damon Runyon fellowships at its May 2009 Fellowship Award Committee review.
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Health
First molecular steps to childhood leukemia identified
A Harvard research based at Massachusetts General Hospital has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) – the most common cancer in children – initiates the disease process. In the July issue of Cell Stem Cell, they describe how expression of this mutation in hematopoietic stem cells (HSCs),…
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Health
Study pinpoints novel cancer gene and biomarker
Dana-Farber Cancer Institute scientists’ discovery of a cancer-causing gene – the first in its family to be linked to cancer – demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and which are mere bystanders. The findings are reported in…
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Campus & Community
I. (Israel) David Todres
(Israel) David Todres, Professor of Paediatrics (Anaesthesia) at Harvard Medical School, died at his home of lymphoma on Sept. 26, 2008. He was 73.
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Health
AML patients benefit from stem cell transplants
A stem cell transplant (SCT) from a compatible donor early in the course of disease is the best approach for the majority of young and middle-aged adult patients with acute myeloid leukemia (AML), according to a new analysis of two dozen clinical studies. The findings of the research, published in the June 10 issue of…
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Health
DFCI cancer research highlights age-related treatment effectiveness, patient cost concerns
New research from the Dana-Farber Cancer Institute highlights age-related responses to colon cancer treatment and patient attitudes toward cost of drugs to manage side effects. Research presented at the American Society of Clinical Oncology‘s annual meeting in Orlando, Fla., Friday (May 29) shows that the vast majority of advanced colon cancer patients in a clinical…
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Health
Genetic testing for breast or ovarian cancer risk may be greatly underutilized
Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other health-care providers. In an online report…
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Health
Broad scientists to sequence multiple myeloma samples
The Multiple Myeloma Research Foundation (MMRF) announced today a collaboration with the Broad Institute of Harvard and MIT to systematically uncover the molecular changes underlying multiple myeloma by whole-genome sequencing of individual patient tumors. The MMRF will provide both patient samples for analysis as well as funding for the project. All data from this collaboration…
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Health
Cancer chemotherapy: An unfolding story
To launch his lecture on cancer chemotherapy, Luke Whitesell ’79, RI ’06 displayed an image of an origami crab: a double visual metaphor. The crab is the traditional symbol of cancer. And Whitesell, a senior research scientist at the Whitehead Institute, has focused on how the artful folding of proteins in cells may offer clues…
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Campus & Community
Despite economy, Daffodil Days still comes up roses
With good news comes the bad news. This year’s Daffodil Days, held on March 16, raised $51,726 in funds for the American Cancer Society — the first time in its 22-year history that this year’s total did not surpass the previous year’s total ($53,329). However, with the economic downturn taken into consideration, “I still think…
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Health
A more direct delivery of cancer drugs to tumors
An interdisciplinary team of researchers at Brigham and Women’s Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology (HST) has demonstrated a better way to deliver cancer drugs directly to tumors. The researchers used specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific…
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Health
HMS professor devises single test for cancers
Imagine visiting a doctor’s office five years from now and, as a routine part of your annual physical, getting an accurate test that can tell whether you have cancer long before you have either symptoms or tumors detectable by other methods. Such a test may be in the offing if early data from both laboratory…
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Health
Breast cancer danger rising in developing countries
Women in developing nations, once thought to have a small chance of contracting breast cancer, are increasingly getting the disease as lifestyles incorporate risk factors common in industrialized nations, panelists at the Harvard School of Public Health (HSPH) said Tuesday (April 14).
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Health
Breast cancer danger rising in developing world
Women in developing nations, once thought to have a small chance of contracting breast cancer, are increasingly getting the disease as lifestyles incorporate risk factors common in industrialized nations, panelists at the Harvard School of Public Health (HSPH) said Tuesday (April 14).
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Health
For cancer cells, genetics alone is poor indicator for drug response
In certain respects, cells are less like machines and more like people. True, they have lots of components, but they also have lots of personality. For example, when specific groups of people are studied in aggregate (conservatives, liberals, atheists, evangelicals), they appear to be fairly uniform and predictable. But when looked at one person at…
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Health
Angiogenesis inhibitor improves brain tumor survival by reducing swelling
The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema – the swelling of brain tissue – and not from any direct anti-tumor effect, according to a study from Harvard researchers at Massachusetts General Hospital (MGH). Their report, to be published…
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Health
Newly identified genetic variants found to increase breast cancer risk
A large-scale effort to identify genetic markers of breast cancer has uncovered two common genetic variants that increase risk of the disease in women of European ancestry. The paper, published in advance online in Nature Genetics on March 29, is part of an ongoing effort led by a team of researchers from the Harvard School…
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Science & Tech
Link found between religious belief, intensive medical care at end of life
In a new study of terminally ill cancer patients, researchers at Dana-Farber Cancer Institute found that those who draw on religion to cope with their illness are more likely to receive intensive, life-prolonging medical care as death approaches — treatment that often entails a lower quality of life in patients’ final days. Previous research showed…
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Health
Blood types indicate greater risk for cancer
Offering a novel clue about the basic biology of pancreatic cancer, researchers at Dana-Farber Cancer Institute have confirmed a decades-old discovery of a link between blood type and the risk of developing the disease.
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Health
Blood type study sheds light on biology of pancreatic cancer
Offering a novel clue about the basic biology of pancreatic cancer, researchers at Dana-Farber Cancer Institute have confirmed a decades-old discovery of a link between blood type and the risk of developing the disease. The finding, published online by the Journal of the National Cancer Institute on March 10, is based on an analysis of…
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Health
Runyon Foundation names fellows from Harvard
The Damon Runyon Cancer Research Foundation has named six Harvard affiliates among its 13 new fellows. The recipients of this prestigious, three-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.
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Campus & Community
Friday marks daffodil deadline
With spring’s anticipated return still weeks away, there’s a beacon of yellow hope. Daffodils are an invigorating component in the American Cancer Society’s (ACS) efforts, and Harvard is again a key participant in Daffodil Days, the ACS’s annual flowery fight to help patients and eradicate cancer.
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Campus & Community
Cancer Society’s daffodils can drive away winter blues
With months until spring’s anticipated return comes a beacon of yellow hope. Daffodils are an invigorating component in the American Cancer Society’s (ACS) efforts, and Harvard is again a key participant in Daffodil Days, the ACS’s annual flowery fight to help patients and eradicate cancer.
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Health
Blavatnik Family Foundation gives Harvard $10M
The Blavatnik Family Foundation, headed by Len Blavatnik, M.B.A. ’89, has given Harvard University two gifts totaling $10 million in support of its scientific and technological research. Half the gift will go to the Eli and Edythe L. Broad Institute of Harvard and MIT to support cancer vaccine research, and half will go to the…