Tag: Cancer
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Nation & World
Saving your self from yourself
“Your gut is a complicated place,” notes Shannon Turley, an assistant professor of pathology at Harvard Medical School. In addition to processing food three or more times a day, an intestine needs to protect you from being damaged by yourself.
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Nation & World
Sengupta wins $4.1 million ‘Era of Hope’ award for breast cancer advances
An assistant professor of medicine at Harvard has won a $4.1 million “Era of Hope” scholar award from the U.S. Defense Department’s Breast Cancer Research Program in support of his cutting-edge, interdisciplinary research aimed at fighting breast and other types of cancer.
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Nation & World
Popular hair-loss drug impedes prostate cancer detection in middle-aged men
Researchers at Brigham and Women’s Hospital (BWH) have found that the prostate specific antigen (PSA) cancer screening test is falsely lowered by a factor of two in middle-aged men who…
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Nation & World
Risk of breast cancer may be associated with red meat consumption
Researchers at Brigham and Women’s Hospital (BWH) have found that eating more red meat may be associated with a higher risk for hormone receptor–positive breast cancers in premenopausal women. This…
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Nation & World
Prostate treatment has risks
A treatment mainstay for prostate cancer puts men at increased risk for diabetes and cardiovascular disease, according to a large observational study published in the Sept. 20 Journal of Clinical Oncology. “Men with prostate cancer have high five-year survival rates, but they also have higher rates of noncancer mortality than healthy men,” says study author…
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Nation & World
New insight into skin-tanning process suggests novel way of preventing skin cancer
Findings from a study led by researchers at Dana-Farber Cancer Institute and Children’s Hospital Boston have rewritten science’s understanding of the process of skin tanning – an insight that has…
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Nation & World
Prostate cancer treatment increases risk of diabetes, heart disease
A treatment mainstay for prostate cancer puts men at increased risk for diabetes and cardiovascular disease, according to a large observational study published in the Sept. 20, 2006, Journal of…
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Nation & World
Sunshine may help prevent breast cancer
Evidence is piling up that boosting vitamin D intake may help prevent breast cancer. One major study of 1,760 women found that the higher the levels of vitamin D in…
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Nation & World
Advances in chemotherapy improve outcomes in select breast cancers
Recent advances in chemotherapy have significantly reduced the risk of disease recurrence and death in breast cancer patients whose tumors are not hormone sensitive, according to a study by researchers…
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Nation & World
Scientists discover new genetic subtypes of common blood cancer
Scientists at Dana-Farber Cancer Institute and collaborators have identified four distinct genetic subtypes of multiple myeloma, a deadly blood cancer, that have different prognoses and might be treated most effectively…
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Nation & World
Brigham pilot program connects people with family histories
A Harvard Medical School instructor at Brigham and Women’s Hospital is spearheading a pilot project to encourage Brigham employees to gather detailed family health histories to give health care officials an edge fighting inherited diseases.
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Nation & World
Advances in stem cell biology presented at symposium
Stem cell science is revolutionizing the field of cancer biology, changing the understanding of the structure of some tumors, and potentially shifting the treatment emphasis from eliminating all tumor cells…
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Nation & World
Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses – a novel strategy called “metronomic” delivery – achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an…
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Nation & World
Cancer link to ‘protein promiscuity’ being studied
When found at abnormally high concentrations, two proteins implicated in many human cancers have the potential to spur indiscriminate biochemical signaling inside cells, chemists at Harvard University have found. Their…
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Nation & World
Gingko may prevent ovarian cancer
Researchers at Brigham and Women’s Hospital have found initial laboratory and epidemiological evidence that, for the first time, demonstrates that ginkgo may help lower a woman’s risk of developing ovarian…
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Nation & World
Herceptin treatment lowers recurrence rate in early breast cancer
Encouraging findings came from an interim report from HERA, an ongoing large, international clinical trial of Herceptin, published Oct. 19, 2005 in the New England Journal of Medicine. The analysis…
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Nation & World
Double trouble: Cells with duplicate genomes can trigger tumors
So-called “double-value” cells are produced by random errors in cell division that occur with unknown frequency. The generation of these genetically unstable cells appears to be a “pathway for generating…
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Nation & World
Subtle changes in normal genes implicated in breast cancer
Scientists found that benign cells surrounding breast cancers undergo epigenetic modifications. The altered gene function causes the microenvironment cells to signal proliferation and increased aggression in the breast tumor cells.…
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Nation & World
Blood vessel drugs halt cancer growth
After decades of surviving peer rejection of his theory of cancer treatment by blocking tiny blood vessels, Judah Folkman has gone on to develop drugs that did what he predicted…
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Nation & World
Scientists identify normal gene driving the growth and survival of melanoma cells
Dana-Farber’s Levi Garraway, M.D., Ph.D., and William Sellers, M.D., the paper’s first and senior authors, and their colleagues reported their findings in the July 7, 2005 issue of the journal…
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Nation & World
Women’s health study: Long-awaited findings of low-dose aspirin and vitamin E in preventing disease
The WHS trial was led by BWH researchers Nancy Cook, Sc.D., and Julie Buring, Sc.D. Its results are published in the July 6, 2005 Journal of the American Medical Association.…
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Nation & World
DNA-scanning technology finds possible sites of cancer genes in chromosomes of lung cancer cell
In a study in the July 1, 2005 issue of the journal Cancer Research, the researchers used single nucleotide polymorphism (SNP) array technology to identify regions of chromosomes where genes…
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Nation & World
A new way to identify cancers is found
Scientists are surprised and delighted that a recently discovered group of small molecules show an unexpected potential for easily distinguishing healthy cells from tumors and one type of cancer from…
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Nation & World
Judah M. Folkman, MD
In the early 1970s Folkman refined his theory that tumors have the capability to grow their own blood vessels, thereby obtaining the nourishment they need to keep growing in a body. Folkman never quit thinking about why this happens and how he might use that information to treat cancer patients.
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Nation & World
Studies chip away at sex hormone roles in prostate and breast cancers
In recent work, Myles Brown and colleagues combined chromatin immunoprecipitation (ChiP) assays with measures of DNA structure and large-scale gene chip analyses to study where, when, and how androgen and…
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Nation & World
New delivery technology paves way for disease therapies
A new way to administer therapeutic RNA molecules that efficiently guides them to cells throughout the body is being reported by researchers at the Harvard-affiliated CBR Institute for Biomedical Research…
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Nation & World
Aspirin use may protect against colon cancer recurrence, reduce risk of death
“Our data are intriguing because they showed that aspirin use notably reduced the risk of recurrence in patients with advanced colon cancer, but more research is needed before any treatment…
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Nation & World
Drug combination boosts survival rate in head and neck cancers
Previous studies have shown that using combination chemotherapy of cisplatin and 5-fu yields a 25 to 50 percent rate of complete pathological responses (the tumor disappeared). Robert Haddad, M.D., and…