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Tag: Bruce Spiegelman
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Nation & World
‘Exercise hormone’ found to target key bone cells
Scientists have discovered that irisin, a hormone released by muscles during exercise, directly acts on key regulatory cells that control the breakdown and formation of bone.
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Nation & World
Antibody halts cancer-related wasting condition
New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle that occurs in about half of all cancer patients, increasing their risk of death. Harvard Professor Bruce Spiegelman demonstrated that symptoms of cachexia in mice improved when given an antibody that blocked the effects of a protein…
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Nation & World
Natural hormone molds leaner bodies in mice
A natural hormone that is increased by physical exercise and by exposure to cold improves blood sugar control, suppresses inflammation, and burns fat to mold leaner bodies in mice, report scientists at the Harvard-affiliated Dana-Farber Cancer Institute.
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Nation & World
‘Beige’ cells key to healthy fat
“Beige fat” cells found in healthy subcutaneous fat in mice play a critical role in protecting the body against the disease risks of obesity, report Harvard researchers at the Dana-Farber Cancer Institute, who say their study findings may have implications for therapy of obesity-related illness in humans.
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Nation & World
Flipping the switch that halts obesity
Flipping a newly discovered molecular switch in white fat cells enabled mice to eat a high-calorie diet without becoming obese or developing the inflammation that causes insulin resistance, report Harvard scientists from Dana-Farber Cancer Institute.
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Nation & World
In obesity battle, beige is the new brown
Scientists at Harvard-affiliated Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans, which they say may have therapeutic potential for treating obesity.
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Nation & World
Reaping benefits of exercise minus the sweat
A team led by researchers at Harvard-affiliated Dana-Farber Cancer Institute has isolated a natural hormone from muscle cells that triggers some of the key health benefits of exercise.
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Nation & World
Advances in type 2 diabetes drugs
Researchers from Harvard-affiliated Dana-Farber Cancer Institute and the Scripps Research Institute in Jupiter, Fla., report they have created prototype drugs having powerful anti-diabetic effects, yet apparently free — at least in mice — of dangerous side effects plaguing some current diabetes medications.
