Tag: basic research

  • Health

    More than a watchdog

    A study in mice shows the nervous system not only detects the presence of Salmonella in the gut but actively stops the organism from infecting the body by shutting the cellular gates that allow bacteria to invade the intestine and spread beyond it.

    Salmonella magnified.
  • Campus & Community

    New faculty: Martin Surbeck

    A new member of the faculty of the Department of Human and Evolutionary Biology, Martin Surbeck runs one of the few bonobo research sites in the world.

    A portrait-style photo of professor in front of a large globe
  • Health

    Inflammatory processes may play role in ALS

    Accumulating evidence suggests that inflammatory processes may play a role in the initiation and progression of amyotrophic lateral sclerosis (ALS).

    3d illustration of nervous network and nerve cells in blue.
  • Health

    CAGEs lock up fats to treat obesity

    Harvard researchers have found an orally administered liquid salt — choline and geranate — that can reduce the absorption of fats from food with no discernable side effects in rats, lowering total body weight by about 12 percent.

    Portrait of a rat.
  • Arts & Culture

    Music everywhere

    Scientists at Harvard published a study on music as a cultural product, which examines what features of song tend to be shared across societies.

    Collage of people playing music around the world.
  • Health

    A gateway to eating disorders

    Young women’s use of diet pills, laxatives for weight control linked with later eating disorder diagnosis.

    A blue measuring tape wrapped around a medicine bottle, with loose pills scattered around the open lid.
  • Science & Tech

    Where we get our sense of direction

    Using virtual reality experiments, Harvard neuroscientists have decoded how fruit fly brains integrate visual cues for navigation. Study also sheds light on a form of short-term memory known as unsupervised learning.

    Fruit fly up close.
  • Science & Tech

    The archaeology of plaque (yes, plaque)

    Christina Warinner says ancient dental plaque offers insights into diets, disease, dairying, and women’s roles of the period.

    Christina Warinner is a new faculty member photographed in front of a display at the Peabody Museum.
  • Science & Tech

    Predicting sudden cardiac death

    Researchers have determined that genetic testing could identify those at risk for cardiac death prior to any symptoms.

    Illustration of heart with puzzle pieces.
  • Science & Tech

    A second look at evolution

    Researchers find clues to evolution in the intricate mammalian vertebral column.

    Graphic of spines in mammals.
  • Science & Tech

    A better candidate for chemo delivery

    A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

  • Science & Tech

    If it ain’t broke, don’t fix it

    Research suggests that errors resulting from variability in motor function are a feature, not a bug, of our nervous system and play a critical role in learning.

    Two researchers talking in a lab.
  • Nation & World

    Targeting incest and promoting individualism

    Harvard Professor Joseph Henrich and a team of collaborators researched how a Roman Catholic Church ban in the Middle Ages loosened extended family ties and changed values and psychology of individuals in the West.

  • Health

    Exercise reduces chronic inflammation, protects heart, study says

    A new study identifies a molecular connection between exercise and inflammation that takes place in the bone marrow and highlights a previously unappreciated role of leptin in exercise-mediated cardiovascular protection.

    Blood vessel with white blood cells
  • Science & Tech

    Combination gene therapy treats age-related diseases

    Wyss Institute, Harvard Medical School study offers hope for single genetic treatment for multiple age-related ills.

    Heart with DNA strands.
  • Health

    Power and pitfalls of gene editing

    CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.

    Panelists at Racliffe discussing gene editing.
  • Science & Tech

    Scientists pinpoint neural activity’s role in human longevity

    The brain’s neural activity, long implicated in disorders ranging from dementia to epilepsy, also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute.

    Mice lacking the protein REST (bottom) showed much higher neural activity in the brain than normal mice.
  • Health

    Learning not to fear

    A study using mindfulness meditation showed changes over time in neural responses to pain and fear. The researchers found that changes in the hippocampus after mindfulness training were associated with enhanced ability to recall a safety memory, and thus respond in a more adaptive way.

    Illustration of meditator with fear shadow
  • Science & Tech

    A reliable clock for your microbiome

    The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging, especially when attempting to study it in living subjects. A new genetic “repressilator” lets scientists noninvasively study its dynamics, acting like a clock that tracks how bacterial growth changes over time with single-cell…

    Colonies of bacteria
  • Science & Tech

    CRISPR enzyme programmed to kill viruses in human cells

    Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

    CrispR illustration
  • Campus & Community

    The magic of the unexpected

    William G. Kaelin Jr., the Sidney Farber Professor of Medicine at Harvard Medical School and the Dana-Farber Cancer Institute, is one of three winners of the 2019 Nobel Prize in physiology or medicine for discovering how cells sense and adapt to changes in oxygen availability, a process critical for survival.

    William G. Kaelin Jr. talks on phone after winning Nobel.
  • Science & Tech

    A shot in the arm for vaccine research

    Immunology research at the Ragon Institute of MGH, MIT, and Harvard has advanced an HIV vaccine into the clinic, and will diversify thanks to a major gift from Phillip T. and Susan M. Ragon.

    Group of students
  • Science & Tech

    Playing our song

    Samuel Mehr has long been interested in questions of what music is, how music works, and why music exists. To help find the answers, he’s created the Music Lab, an online, citizen-science project aimed at understanding not just how the human mind interprets music, but why music is a virtually ubiquitous feature of human societies.

  • Science & Tech

    A silly-sounding prize for some serious science

    Harvard-trained researchers win Golden Goose Awards from the American Association for the Advancement of Science.

  • Science & Tech

    Hunters, herders, companions: Breeding dogs has reordered their brains

    Erin Hecht, who joined the faculty in January, has published her first paper on our canine comrades in the Journal of Neuroscience, finding that different breeds have different brain organizations owing to human cultivation of specific traits.

    Researcher with two dogs
  • Science & Tech

    Pancreas on a chip

    Islet-on-a-chip technology allows clinicians to easily determine the therapeutic value of beta cells for any given patient.

    Islet on a chip
  • Science & Tech

    Exposing how pancreatic cancer does its dirty work

    New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

    Pancreatic cancer cell
  • Science & Tech

    How a zebrafish model may hold a key to biology

    Martin Haesemeyer set out to build an artificial neural network that worked differently than fish’s brains, but what he got was a system that almost perfectly mimicked the zebrafish — and that could be a powerful tool for understanding biology.

    Researchers looking at zebrafish
  • Science & Tech

    Clever crows

    A new paper, co-authored by Dakota McCoy, a graduate student working in the lab of George Putnam Professor of Biology David Haig, suggests that, after using tools, crows were more optimistic.

    Crow with tool
  • Science & Tech

    How the moon came to be

    A fourth-year graduate student in the lab of Professor of Geochemistry Stein Jacobsen, Yaray Ku is working on a project aimed at understanding how the moon formed, and to do it, she’s working with actual lunar samples.

    Yaya Ku researches the moon