A study of plaque production at single-cell level holds promise to help improve Alzheimer’s treatment.
Rett syndrome is a relatively common neurodevelopmental disorder, the second most common cause of intellectual disability in girls after Down syndrome. Building on 2004 findings, Harvard researchers identified a faulty signaling pathway that, when corrected in mice, improves the symptoms of Rett syndrome.
Massachusetts General Hospital researchers are working on a topical treatment that may be available for those with seborrheic keratosis (SK), or liver spots. SKs vary in color from tan to black, can be flat or raised, and range in size from quite small to an inch or more across.
Researchers have found that cancer begins after activation of an oncogene or loss of a tumor suppressor, and involves a change that takes a single cell back to a stem cell state. They believe this model may apply not only to melanoma, but to most if not all cancers.
Researchers at MIT’s David H. Koch Institute for Integrative Cancer Research, in collaboration with scientists at the Harvard Stem Cell Institute and several other institutions, have developed an implantable device that in mice shielded insulin-producing beta cells from immune system attack for six months — a substantial proportion of life span.
Oral contraceptives taken just before or during pregnancy do not increase the risk of birth defects, according to a new study by researchers from the Harvard T.H. Chan School of Public Health and the Statens Serum Institut in Denmark.
Scientists gave little thought to the neurological effects of dance until relatively recently, when researchers began to investigate the complex mental coordination that dance requires.
A large new study of twins has found that a person whose twin is diagnosed with cancer stands an increased risk of also developing a form of cancer.
A multicomponent, microfluidic small airway-on-a-chip model provides new opportunities to study human lung inflammatory disorders such as chronic obstructive pulmonary disease (COPD) and asthma, and to test preclinical drug candidates outside the human body.
Using a visual test that is known to prompt different reactions in autistic and normal brains, Harvard researchers have shown that those differences were associated with a breakdown in the signaling pathway used by one of the brain’s chief inhibitory neurotransmitters.
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A study from Brigham and Women’s Hospital offers a new view of how cancer cells extend their reach, co-opting and transforming normal cells through “metastatic hijacking.” The researchers also found that in preclinical models, pharmacological intervention can prevent this from occurring.
In a new study, the Wyss Institute’s human-gut-on-a-chip technology is used to co-culture gut microbiome and human intestinal cells, which could spur innovation of novel therapies for inflammatory bowel diseases.
A Harvard study links chemicals used in flavored electronic cigarettes to cases of severe respiratory disease.
Frank Hu, a professor of nutrition and epidemiology at the Harvard T.H. Chan School of Public Health and the principal investigator of the diabetes component of the landmark Nurses’ Health Study, responded to the latest Center for Disease Control and Prevention findings in an interview with the Gazette.
The Harvard Chan School’s Walter Willett discusses recent findings on obesity, blood pressure, and smoking.
An independent group of 20 international experts has issued a scathing analysis of the global response to the 2014-15 Ebola outbreak in West Africa.
During an Ed Portal discussion, Harvard Professor Ashish Jha examined where the global health system failed when Ebola began to spread.
Faculty and student panel examines efforts to make polio the second human disease to be eradicated during the “Every Last Child" event at Radcliffe.
A team led by Harvard statistician Samuel Kou has devised a new system for tracking flu outbreaks in real time.
Harvard addiction specialist on FDA’s OxyContin OK: We have to respond to both patients and population health, a tricky task.