Tag: Nature Structural & Molecular Biology
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Health
Solving the problem of shape-shifters
Investigators at Harvard-affiliated Massachusetts General Hospital (MGH) may have found a way to solve a problem that has plagued ligand-mimicking integrin inhibitors, a group of drugs that have the potential to treat conditions ranging from heart attacks to cancer metastasis.
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Health
Genetic mechanics
As reported in the online version of Nature Structural & Molecular Biology on Feb. 5, researchers have produced 3-D images of the protein system that works to repair DNA. The images reveal that the proteins can actually alter their shape in what amounts to a genetic “pat-down,” or a way for the mechanism to identify…
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Health
Struttin’ its stuff
Harvard researchers have found that a tiny motor inside of us called dynein, one tasked with shuttling vital payloads throughout the cell’s intricate highway infrastructure, staggers, which is quite contrary to the regular, efficient poise of its fellow motors.
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Health
Understanding interference
In a discovery that might eventually lead to new biomedical treatments for disease, researchers from Harvard’s Department of Molecular and Cellular Biology have identified two types of RNA that are able to move between cells as part of a process called RNA-interference (RNAi).