Tag: Gökhan Hotamisligil
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Campus & Community
Gokhan Hotamisligil receives honor for the Study of Obesity
Gökhan Hotamisligil, the J.S. Simmons Professor of Genetics and Metabolism and chair of the Department of Genetics and Complex Diseases at the Harvard School of Public Health, will receive the prestigious Wertheimer Award from the International Association for the Study of Obesity in July in Stockholm.
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Health
A molecule that destroys normal metabolism is found
Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes, according to the results of a new study led by researchers at the Harvard School of Public Health (HSPH). The research specifically links…
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Science & Tech
New class of hormone from “healthy fat cells” benefits body metabolism in mice
Scientists at the Harvard School of Public Health (HSPH) have identified in mice a newly discovered class of hormones — lipokines. In tomorrow’s issue of the journal Cell they report that lipokine is a molecule in mice that helps stop, or even reverses obesity-related conditions such as insulin resistance and “fatty liver.” Lipokines are hormones…
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Health
Key gene discovered for obesity and diabetes
Obesity is closely associated with insulin resistance and is one of the leading risk factors for type 2 diabetes. Both affect more than 50 percent of the U.S. population. Little has been known about the molecular mechanisms linking these two metabolic diseases. Both are associated with a wide range of inflammatory molecular activity in fatty…
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Health
Researchers identify genes that control development of fat tissues
Until now, no one knew the specific trigger that controls the extent to which cells called preadipocytes turn into fat cells. Harvard researchers have identified the genes GATA-2 and GATA-3 as the molecular gatekeepers of that transition. When the genes are defective or missing, preadipocytes change into fat cells and, conversely, when the genes are…