Tag: gene editing

  • Nation & World

    Innovative tool offers hope for children with rapid-aging disease

    Several hundred children worldwide live with progeria, a deadly premature aging disease.

    7 minutes
  • Nation & World

    A promise to a friend

    Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.

    4 minutes
    Person wearing hearing aid.
  • Nation & World

    Capabilities of CRISPR gene editing expanded

    Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.

    2 minutes
    DNA strands.
  • Nation & World

    A crisper CRISPR

    Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

    6 minutes
    David Liu.
  • Nation & World

    Power and pitfalls of gene editing

    CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.

    5 minutes
    Panelists at Racliffe discussing gene editing.
  • Nation & World

    Single letter speaks volumes

    Scientists have used an optimized version of the CRISPR-Cas9 gene-editing system to prevent hearing loss in so-called Beethoven mice, which carry a genetic mutation that causes profound hearing loss in humans and mice alike.

    9 minutes
  • Nation & World

    Forward thinking

    Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.

    6 minutes
    Scientists
  • Nation & World

    Editing genes at the source

    Study shows how genes could be edited in stem cells within intact organs, without having to remove them from their normal environment. The new approach could treat a variety of diseases.

    5 minutes
    uninjected and injected cells
  • Nation & World

    Researchers ID molecules that rein in CRISPR systems

    Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.

    3 minutes
    3D render of the CRISPR-Cas9 genome editing system
  • Nation & World

    Perspectives on gene editing

    Harvard researchers, others share their views on key issues in the field

    16 minutes
    Hand unlocking genetic data.
  • Nation & World

    CRISPR’s breakthrough implications

    CRISPR pioneer Jennifer Doudna discussed the gene-editing technology’s rapid spread and the need for a robust discussion about the ethics of its applications.

    6 minutes
  • Nation & World

    Seeing promise, and limits, in embryo edit

    The disease-targeting embryo edit at Oregon Health & Science University signals a path for “those rare situations where the genes really are life-threatening,” says Harvard bioethicist Robert Truog.

    5 minutes
  • Nation & World

    A shot against heart attacks?

    Harvard Stem Cell Institute scientists collaborating with researchers at the University of Pennsylvania have developed a “genome-editing” approach for permanently reducing cholesterol levels in mice through a single injection, a development with the potential to reduce the risk of heart attacks in humans by 40 to 90 percent.

    6 minutes