Tag: gene editing
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Nation & World
Innovative tool offers hope for children with rapid-aging disease
Several hundred children worldwide live with progeria, a deadly premature aging disease.
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Nation & World
A promise to a friend
Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.
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Nation & World
Capabilities of CRISPR gene editing expanded
Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.
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Nation & World
A crisper CRISPR
Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.
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Nation & World
Power and pitfalls of gene editing
CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.
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Nation & World
Single letter speaks volumes
Scientists have used an optimized version of the CRISPR-Cas9 gene-editing system to prevent hearing loss in so-called Beethoven mice, which carry a genetic mutation that causes profound hearing loss in humans and mice alike.
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Nation & World
Forward thinking
Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.
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Nation & World
Researchers ID molecules that rein in CRISPR systems
Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.
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Nation & World
Perspectives on gene editing
Harvard researchers, others share their views on key issues in the field
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Nation & World
CRISPR’s breakthrough implications
CRISPR pioneer Jennifer Doudna discussed the gene-editing technology’s rapid spread and the need for a robust discussion about the ethics of its applications.
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Nation & World
Seeing promise, and limits, in embryo edit
The disease-targeting embryo edit at Oregon Health & Science University signals a path for “those rare situations where the genes really are life-threatening,” says Harvard bioethicist Robert Truog.
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Nation & World
A shot against heart attacks?
Harvard Stem Cell Institute scientists collaborating with researchers at the University of Pennsylvania have developed a “genome-editing” approach for permanently reducing cholesterol levels in mice through a single injection, a development with the potential to reduce the risk of heart attacks in humans by 40 to 90 percent.