Profiles of Progress

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Reeling in a big scientific discovery
William Kaelin pursued Nobel-winning findings using a fisherman’s instinct
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‘Shared humanity’ is their call to action, here and there
No letup in doctors’ commitment to easing suffering in world’s danger zones
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Rewriting genetic destiny
David Liu, Breakthrough Prize recipient, retraces path to an ‘incredibly exciting’ disease fighter: ‘This is the essence of basic science.’
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Long trail from 1992 discovery to 2024 Nobel
Gary Ruvkun recounts years of research, which gradually drew interest, mostly fueled by NIH grants
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Health
‘Hopeful message’ on brain disease
Researcher Sanjula Singh has looked at stroke, dementia, late-life depression for years, finds lifestyle changes make big difference
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Science & Tech
Highly sensitive science
David Ginty probes pleasure and pain to shed light on autism and other conditions
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Health
What might cancer treatment teach us about dealing with retinal disease?
Joan Miller’s innovative thinking led to therapies for macular degeneration that have helped millions, made her better leader
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Nation & World
Let’s not send low-income students back to the ’80s
Financial aid red tape nearly derailed Susan Dynarski’s undergrad dreams. Now she sees decades of progress under threat.
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Health
We know exercise is good for you. Why? He‘s working on it.
Expanding on decades of research, a new study seeks to pinpoint movement’s molecular benefits
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Nation & World
Things money can’t buy — like happiness and better health
That’s according to the Harvard Study of Adult Development, which over its 87-year run has generated data that benefits work on other issues
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Tips for staying alive, decades in the making
JoAnn Manson has spent her career researching – and highlighting – how everyday choices influence health
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How just a fishing expedition helped lead to GLP-1
Story of game-changing therapy illustrates crucial role of fundamental research breakthroughs
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Fighting Alzheimer’s one discovery at a time
‘I was just following the science.’