The Harvard Gazette

Estrogen

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Low estrogen levels can make women more vulnerable to trauma at some points in their menstrual cycles, while high levels of the female sex hormone can partially protect them from emotional disturbance, according to new research by Mohammed Milad (left) and Kelimer Lebron-Milad.

Estrogen and female anxiety

Study suggests lower levels can lead to more mood disorders

Health|

DateAugust 9, 2012June 26, 2019

Drugs such as tamoxifen block estrogen from entering the receptor, thereby thwarting the growth process. Photo by Bill Branson

When estrogen isn’t the culprit

Study finds new points of attack on breast cancers not fueled by estrogen

Health|

DateJuly 11, 2011June 19, 2019

Breast cancer geneticist Kornelia Polyak (pictured) and colleagues from the Harvard-affiliated Dana-Farber Cancer Institute, have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.

What’s behind aggressive breast cancer

Potential new drug target for hard-to-treat ‘triple-negative’ disease

Health|

DateJune 1, 2011September 12, 2019

Researchers led by Ronald A. DePinho (above), a Harvard Medical School professor of genetics, say their work shows for the first time a dramatic reversal of many aspects of age-related degeneration in mice, a milestone in aging science achieved by engineering mice with a controllable telomerase gene. The projection of chromosomes seen here shows telomeres (highlighted in red) on their ends.

Partial reversal of aging achieved in mice

Control of telomerase gene appears to control process

Health|

DateNovember 28, 2010March 6, 2019