Tag: Derrick Rossi

  • Health

    Toward safer bone-marrow transplants

    The combination of the antibody CD117 and the drug saporin selectively targets blood stem cells, making transplantation safer by limiting collateral damage caused by the current standard of treatment, chemotherapy, and radiation.

    4 minutes
    hematopoietic stem cells
  • Health

    A promising strategy against HIV

    Harvard Stem Cell Institute researchers at Massachusetts General and Boston Children’s hospitals for the first time have used a relatively new gene-editing technique to create what could prove to be an effective technique for blocking HIV from invading and destroying patients’ immune systems.

    6 minutes
  • Health

    New hope in regenerative medicine

    Harvard Stem Cell Institute researchers at Boston Children’s Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells have the functional hallmarks of HSCs and are able to self-renew like those cells.

    4 minutes
  • Health

    ‘Another set of fingers’

    An interdisciplinary group of leading Harvard geneticists and stem cell researchers has found a new genetic aspect of cell reprogramming that may ultimately help in the fine-tuning of induced pluripotent stem cells (iPS) into specific cell types.

    4 minutes
  • Health

    Breakthrough in cell reprogramming

    A group of Harvard Stem Cell Institute researchers has made such a significant leap forward in reprogramming human adult cells that HSCI co-director Douglas Melton said the institute will immediately begin using the new method to make patient- and disease-specific induced pluripotent stem cells, known as iPS cells.

    9 minutes