Harvard stem cell scientists have successfully converted skins cells from patients with early onset Alzheimer’s into the types of neurons affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells.
Hospital stewardship programs, community education, and legal changes to allow pharmaceutical companies to profit longer from new antibiotics are among reforms that experts suggest to fight drug-resistant bacteria.
Researchers have created embryonic stem cells without an embryo. This discovery of a novel reprogramming method of adult cells, without introducing external genetic material, could dramatically shift stem cell research.
The waterproof, light-activated glue developed by researchers at Harvard-affiliated Brigham and Women’s Hospital and Children’s Hospital Boston and their colleagues at MIT can successfully secure biodegradable patches to seal holes in a beating heart.
In the largest study of its kind, people who ate a daily handful of nuts were found to be 20 percent less likely to die from any cause over a 30-year period than those who didn’t consume nuts, say Harvard researchers.
Targeted nanotherapy is the wave of the medical future, according to Omid Farokhzad, a Harvard Medical School and Brigham and Women’s Hospital researcher who has two nanoparticle-based therapies in clinical trials and a slew of ideas for new ways to put the tiny capsules to work for human health.
Harvard research shows that while only 10 percent of adults with sore throat have strep, the only common cause of sore throat requiring antibiotics, the national antibiotic prescribing rate for adults with sore throat has remained at 60 percent.
On Oct. 9, 2012, Taliban gunmen shot 15-year-old Malaa Yousafzai in the head as she rode home from school on a bus. She was simply trying education. On Sept. 27, Yousafzai was in Cambridge to receive the 2013 Peter J. Gomes Humanitarian of the Year Award.
People who are married when diagnosed with cancer live longer than those who are not married. Married patients also tended to have cancers diagnosed at an earlier stage, according to Harvard researchers.
Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.
Benedict Nwachukwu, graduating with a dual M.D./M.B.A. degree, wants to apply the management skills he learned at Harvard Business School to the medical problems he finds in orthopedics and in global health.
MatriTarg Laboratories, a venture created by a team of Harvard fellows seeking new ways to diagnose and treat solid organ fibrosis, claimed the grand prize in the inaugural Deans’ Health and Life Sciences Challenge.
Founding donor Hansjörg Wyss doubled his gift to Harvard’s Wyss Institute for Biologically Inspired Engineering from $125 million to $250 million to the University to further advance the institute’s pioneering work.
Researchers from Harvard-affiliated Brigham and Women’s Hospital (BWH) are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce stem cells to become bone cells without the need of additional bone-inducing factors.
Two Harvard Stem Cell Institute researchers have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for the form of age-related heart failure that affects millions of Americans, a study says.
Members of the Harvard community responded to the Boston Marathon attacks and offered thoughts about both the physical and mental injuries they caused.
A new study led by Harvard Medical School Professor Dennis Selkoe provides specific, pre-clinical scientific evidence supporting the concept that prolonged and intensive stimulation by an enriched environment may have beneficial effects in delaying one of the key negative factors in Alzheimer’s disease.
he National Football League Players Association (NFLPA) has awarded Harvard Medical School a $100 million grant to create a transformative 10-year initiative — Harvard Integrated Program to Protect and Improve the Health of NFLPA Members.
In an airplane crisis—an engine failure, a fire—pilots pull out a checklist to help with their decision-making. But in an operating room crisis—massive ...
Researchers from Harvard-affiliated Brigham and Women’s Hospital have found that some patients who receive generic drugs that vary in their color are over 50 percent more likely to stop taking the drug, leading to potentially important and potentially adverse clinical effects.
In a study from Harvard-affiliated Brigham and Women’s Hospital, researchers used a novel method to identify the new heart cells and describe their origins.
A Harvard panel examined the problem of clinics around the world that provide stem cell treatments for intractable conditions. Although there is no medical evidence of the treatments’ effectiveness, such clinics have drawn thousands of patients from many countries.
Joseph E. Murray, emeritus professor of surgery at Harvard Medical School, whose many breakthroughs included the first successful kidney transplant, died Nov. 26, after suffering a hemorrhagic stroke at his Wellesley, Mass., home on Thanksgiving. He was 93.
Researchers designed a chip that uses a 3-D DNA network made up of long DNA strands with repetitive sequences that — like the jellyfish tentacles — can detect, bind, and capture certain molecules.
Researchers have found that a protozoan parasite causing an STD that affects a quarter of a million people yearly is fueled in part by its own viral symbiont. Antibiotics that simply kill the parasite are not the solution.
“We found that adding low amounts of physical activity to one’s daily routine, such as 75 minutes of brisk walking per week, was associated with increased longevity: a gain of 1.8 years of life expectancy after age 40, compared with doing no such activity,” explained Harvard Medical School Professor of Medicine I-Min Lee.
Harvard researchers have worked for years to understand better the familiar mystery of sleep, highlighting not only what happens when we close our eyes, but also the effects on us when we don’t.
Harvard researchers at Dana-Farber Cancer Institute find that aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but it has no effect on patients who lack the mutation.
Researchers at Harvard-affiliated Brigham and Women’s Hospital have pinpointed when seemingly innocuous skin pigment cells mutate into melanoma.
According to a study by researchers at Harvard-affiliated Brigham and Women’s Hospital, women who took ibuprofen or acetaminophen two or more days per week had an increased risk of hearing loss.
New research from Brigham and Women’s Hospital (BWH) finds that women with high job strain are more likely to experience a cardiovascular-related event compared with women with low job strain. These findings are published in the open access journal PLoS ONE.
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard have developed a novel biomimetic strategy that delivers life-saving nanotherapeutics directly to obstructed blood vessels, dissolving blood clots before they cause serious damage or even death.
Researchers at Harvard Medical School and Harvard-affiliated Massachusetts General Hospital have found that the body’s immune response to heart attacks actually worsens atherosclerosis, increasing future heart attack risk, according to a study published in the journal Nature.
The first complete artificial heart transplant in New England was performed at Harvard-affiliated Brigham and Women’s Hospital.
A study by researchers at Harvard-affiliated Brigham and Women’s Hospital adds to the list of medical problems that exercise eases, showing that vigorous activity reduces a woman’s risk of developing the skin condition psoriasis by 25 to 30 percent over the study subject who exercised the least.
A “proof-of-concept” study that applies financial portfolio theory to federal life science research funding shows that potentially significant gains are available by altering the allocation of funding by the National Institutes of Health.
A new study by Harvard researchers at Brigham and Women’s Hospital (BWH) finds that a high intake of flavonoid-rich berries, such as strawberries and blueberries, over time, can delay memory decline in older women by two and a half years.
Scientists from Harvard-affiliated Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive “triple-negative” breast cancers and certain ovarian cancers are likely to respond to platinum-based chemotherapies.
Scientists at Dana-Farber Cancer Institute have identified a subtype of ovarian cancer able to build its own blood vessels, suggesting that such tumors might be especially susceptible to “anti-angiogenic” drugs that block blood vessel formation
A team led by researchers at Harvard-affiliated Dana-Farber Cancer Institute has isolated a natural hormone from muscle cells that triggers some of the key health benefits of exercise.
Harvard Medical School Instructor Stephanie Kayden’s educational life came full circle this semester, when she taught a humanitarian studies course in Emerson Hall, where, as an undergraduate philosophy concentrator she honed her own reasoning skills years ago.
Harvard Medical School (HMS) Assistant Professor Louise Ivers was awarded the Bailey K. Ashford Medal by the American Society of Tropical Medicine and Hygiene.
Researchers at Brigham and Women’s Hospital and the Dana-Farber Cancer Institute are collaborating on a massive, long-term effort to collect and analyze tumor tissue from 10,000 cancer patients annually. The researchers hope the data will enable them to understand better how tumors behave, while providing opportunities to test new therapies.
Researchers from Harvard-affiliated Brigham and Women’s Hospital evaluated whether eliminating co-payments for specific medications following a heart attack would increase adherence and improve outcomes in patients.
Researchers have decoded the genome of an unlikely ally in the fight against cancer and aging, the naked mole rat, to find clues on why it resists the disease and lives 10 times as long as ordinary mice.
In clinical settings, simple 2-D displays of human arteries are more effective than traditional 3-D rainbow models, according to Harvard researchers.
Report reveals that readily available and affordable cancer prevention, treatment, and pain relief interventions could decrease deaths and improve the lives of millions in developing countries.
Harvard researchers have cloned stem cells from the airways of the human lung and have shown that these cells can form into the lung’s alveoli air sac tissue. Mouse models suggest that these same stem cells are deployed to regenerate lung tissue during acute infection, such as during influenza.
Fourteen Harvard surgeons, supported by 36 anesthesiologists, radiologists, nurses, and other medical personnel at Harvard-affiliated Brigham and Women’s Hospital, worked for 12 hours to give a new pair of hands to a 65-year-old Revere man who lost both arms below the elbows and both legs below the knees as a result of a septic infection in 2002.
In a new research paper published in the Proceedings of the National Academy of Sciences Early Edition online, Harvard-affiliated researchers identify a transcriptional biomarker that may assist in the monitoring of Huntington's disease activity and in the evaluation of new medications.