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Tag: Molecular Pharmacology
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Campus & Community
Nussbaum dies at 81
Retired Associate Professor of Biological Chemistry and Molecular Pharmacology Alexander Leopold Nussbaum of Newton, Mass., died June 22, 2007. He was 81.
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Health
Lab moves genomic testing into the clinic
The earliest symptom of the inherited heart condition hypertrophic cardiomyopathy can be sudden death at a tragically young age. Harvard Medical School researchers discovered the first human gene underlying the disorder 15 years ago, but clinical genetic testing to identify those people at risk just became available last year. About the same time, another genetic…
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Health
Disparate proteins structurally identical
Gerhard Wagner, the Elkan Blout professor of biological chemistry and molecular pharmacology, and Tucker Collins, the S. Burt Wolbach professor of pathology at Harvard Medical School and Children’s Hospital, made a crucial connection between two unrelated proteins. They were studying a particular type of protein when a database search for proteins with similar structures turned…
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Health
RNA-making apparatus seen to uncoil and recoil DNA
Eukaryotic cells like to keep their DNA under wraps, winding the long strands of nucleic acid around millions of little protein complexes. This bead-on-a-string structure, called chromatin, ensures that the DNA is protected and also helps to condense the long strands of nucleic acid so they more easily are accommodated in the nucleus. Chromatin also…
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Health
Enzyme pair joins fight against drug-resistant bacteria
Scientists have been striving to develop antibiotics against drug-resistant bacterial strains. Most attempts have been plagued by a lack of molecular tools for manipulating — and ultimately improving — the structure of naturally occurring antibiotics. Harvard Medical School researchers Heather Losey, Christopher T. Walsh, and their colleagues reported in the Dec. 16, 2002 issue of…