Tag: Harvard Stem Cell Institute
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Health
Glimpsing the birth of our earliest reproductive cells
It has long been a mystery how the developing embryo designates those rare, precious cells destined to produce sperm and eggs — enabling us to have offspring – since these…
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Health
Human cardiac master stem cells identified
Harvard Stem Cell Institute researchers at Massachusetts General Hospital have identified the earliest master human heart stem cell from human embryonic stem cells – ISL1+ progenitors – that give rise…
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Health
Safer stem cells for therapy
When stem cell researchers in Japan and the United States announced in 2007 that they had developed long-sought methods to return fully developed adult human cells to an embryonic-like state, the world of stem cell research was turned upside down.
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Science & Tech
Massachusetts Lt. Governor tours Harvard research facilities
Massachusetts Lt. Governor Timothy Murray on Wednesday toured Harvard labs in both Cambridge and Boston. “The Patrick Administration has been very supportive of the university research sector in Massachusetts and…
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Science & Tech
Five at Harvard named HHMI Early Career Scientists;
Five Harvard scientists are among 50 young scientists nationwide who will have their work supported for the next six years by a new initiative from the Howard Hughes Medical Institute…
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Health
Mechanism directing stem cells to their destination identified;
Harvard Stem Cell Institute (HSCI) researchers have for the first time identified in mice a cellular mechanism that directs stem cells to their ultimate destination in the body. The finding…
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Science & Tech
Science, engineering programs advancing
Harvard President Drew Faust today renewed the University’s commitment to the vision of advancing interdisciplinary, collaborative science in general, and the Department of Stem Cell and Regenerative Biology (SCRB), the…
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Health
Stem Cell Research: The Quest Resumes
“After eight years of political ostracism, stem-cell scientists like Harvard’s Douglas Melton are coming back into the light — and making discoveries that may soon bring lifesaving breakthroughs. Scientific inspiration…
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Health
Stem cell researcher honored by President George W. Bush
Harvard Stem Cell Institute (HSCI) scientist Kevin Eggan today was cited by President George W. Bush for his work in advancing the field of stem cell science on both scientific…
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Health
Another step forward in ALS and stem cell research
A Harvard Stem Cell Institute research team has succeeded in deriving spinal motor neurons from human embryonic stem cells, and has then used them to replicate the Amyotrophic Lateral Sclerosis (ALS) disease process in a laboratory dish.
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Health
Some blood-system stem cells reproduce more slowly than expected
A research collaboration lead by Harvard Stem Cell Institute researchers at Massachusetts General Hospital (MGH) has found a subpopulation of hematopoietic stem cells, which generate all blood and immune system…
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Health
Another step forward in cell reprogramming
Imagine, if you can, a day within the next decade when a physician-scientist could remove a skin cell from your arm, and with a few chemicals turn that fully formed adult cell into a dish of stem cells genetically matched to you.
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Health
Important new step toward producing stem cells for human treatment
A team of Harvard Stem Cell Institute (HSCI) scientists has taken an important step toward producing induced pluripotent stem (iPS) cells that are safe to transplant into patients to treat…
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Health
Efficiency of producing iPS cells markedly improved
Some of the most challenging obstacles limiting the reprogramming of mature human cells into stem cells may not seem quite as daunting in the near future. Two independent research groups,…
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Health
Harvard Stem Cell Institute researchers turn one form of adult mouse cell directly into another
In a feat of biological prestidigitation likely to turn the field of regenerative medicine on its head, Harvard Stem Cell Institute (HSCI) co-director Doug Melton and post doctoral fellow Qiao…
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Health
Neurons created from skin cells of elderly patients with ALS
Less than 27 months after announcing that he had institutional permission to attempt the creation of patient- and disease-specific stem cell lines, Harvard Stem Cell Institute (HSCI) principal faculty member Kevin Eggan proclaimed the effort a success — though politically imposed restrictions and scientific advances prompted him to use a different technique than originally planned.
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Health
Daley and colleagues create 20 disease-specific stem cell lines
Harvard Stem Cell Institute (HSCI) researcher George Q. Daley, associate director of the Stem Cell Program at Children’s Hospital Boston, has with HSCI colleagues Chad Cowan and Konrad Hochedlinger of Massachusetts General Hospital (MGH) produced a robust new collection of disease-specific stem cell lines, all of which were developed using the new induced pluripotent stem…
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Health
Daley and colleagues create 20 disease-specific stem cell lines
Harvard Stem Cell Institute (HSCI) researcher George Q. Daley, associate director of the Stem Cell Program at Children’s Hospital Boston, has with HSCI colleagues Chad Cowan and Konrad Hochedlinger of Massachusetts General Hospital (MGH) produced a robust new collection of disease-specific stem cell lines, all of which were developed using the new induced pluripotent stem…
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Health
GlaxoSmithKline and Harvard Stem Cell Institute announce major collaboration agreement
GlaxoSmithKline (GSK) and the Harvard Stem Cell Institute (HSCI) today announced that they have entered into a five-year, $25 million-plus collaborative agreement to build a unique alliance in stem cell…
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Health
Amy Wagers – focusing on stem cell biology
Twenty minutes after her weekly lab meeting is scheduled to begin, Amy Wagers rushes into a conference room on the fourth floor of the Joslin Diabetes Center, where her lab…
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Health
Stem cells used to treat muscular dystrophy in mice
Harvard Stem Cell Institute researchers at the Joslin Diabetes Center have for the first time demonstrated that transplanted muscle stem cells can both improve muscle function in mice with a…
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Health
Scientists use genomic tools to create maps of DNA methylation
Much of the field of stem cell biology and development remains uncharted territory. Just as famous explorers and astronomers mapped out landmasses and constellations, researchers are working fervently to chart…
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Health
New source of heart stem cells discovered
Harvard Stem Cell Institute(HSCI) researchers at Children’s Hospital Boston are continuing to document the heart’s earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that…
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Health
Genomic analysis gives new insights into cellular reprogramming
A cross-disciplinary team of Harvard University, Whitehead Institute, and Broad Institute researchers has uncovered significant new information about the molecular changes that underlie the process by which adult cells can…
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Health
Experiment advances understanding of cell reprogramming
The announcement last year by scientists in Japan, at the Harvard Stem Cell Institute (HSCI), and at the Whitehead Institute that they had each — independently — coaxed adult cells…
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Science & Tech
Presidential election will bring change in federal stem cell policy
Embryonic stem cell research will likely have a more sympathetic ear in the White House after November’s presidential election, but a panel of speakers said last night that an era…
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Health
Reprogrammed adult skin cells treat Parkinson’s disease in animal model
Researchers at the Whitehead Institute and Harvard Stem Cell Institute(HSCI) have reported successfully reducing symptoms in a Parkinson’s disease rat model by using dopamine producing neurons derived from reprogrammed adult…
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Health
Stem cells open window on disease processes
A panel of Harvard Stem Cell Institute experts said recently that stem cell research’s biggest impact on patients’ health likely won’t come from therapies that inject stem cells or implant…
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Health
Major step forward in understanding cell reprogramming
Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like state…