Tag: digoxin

  • Nation & World

    Enzyme interference

    Researchers discovered that Eggerthella lenta — a bacterium found in the guts of more than 30 percent of the population — can metabolize the cardiac drug digoxin in high enough quantities to render it ineffective. Now, a team of researchers has identified the culprit gene that produces the digoxin-metabolizing enzyme.

    6 minutes
  • Nation & World

    Plants with biosensors may light the way

    A team of researchers from the Wyss Institute and Harvard Medical School has developed a new method for engineering a broad range of biosensors to detect and signal virtually any desired molecule using living eukaryotic cells. Its applications could range from detecting hormones to benefiting agriculture.

    4 minutes
  • Nation & World

    Bacterial blockade

    Harvard researchers have identified a pair of genes that appear to be responsible for allowing a specific strain of bacteria in the human gut to break down Lanoxin — a widely prescribed cardiac drug — into an inactive compound, as well as a possible way to turn the process off.

    4 minutes
  • Nation & World

    Life partner

    Researchers in the Harvard lab of Bauer Fellow Peter Turnbaugh are seeking to understand how the microbes that live in our intestines affect the drugs we take and the food we eat.

    4 minutes