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Tag: Bauer Center for Genomics Research
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Campus & Community
Cancer link to ‘protein promiscuity’ being studied
When found at abnormally high concentrations, two proteins implicated in many human cancers have the potential to spur indiscriminate biochemical signaling inside cells, chemists at Harvard University have found. Their finding may expand scientists’ current understanding of oncogenesis – that cancer arises when an oncoprotein becomes overactive, ramping up the biochemical pathways that it normally…
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Science & Tech
Method automates capture of cell image data
A new type of drug profiling will be useful in identifying the biological targets of experimental compounds and predicting drug toxicity. “This work brings microscopy into the ‘omics’ era,” said Timothy Mitchison, the Hasib Sabbagh professor of systems biology, codirector of the Harvard Medical School Institute of Chemistry and Cell Biology (ICCB) and co-author on…
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Health
Identifying the source of all disease
In a major leap toward learning the basics of human biology and what makes it go awry, Harvard researchers have built the prototype of a high-tech chip that rapidly identifies proteins and their functions. Such chips may ultimately help to determine which proteins are responsible for which diseases. “We don’t yet know how many different…