A panel of Harvard Stem Cell Institute experts said recently that stem cell research’s biggest impact on patients’ health likely won’t come from therapies that inject stem cells or implant…
The Massachusetts General Hospital (MGH) has received a five-year, $20.5 million grant from the Bill & Melinda Gates Foundation to expand an international program investigating the biological factors underlying immune system control of HIV, the virus that causes AIDS. The grant provides support to the International HIV Controllers Study, which currently involves researchers from more than a dozen countries and has the overall goal of discovering information that can guide design of a vaccine to limit viral replication in HIV-infected individuals. A primary focus will be to understand the genetic and immunological factors that have allowed a few individuals to control HIV naturally without the need for medications, some for more than 25 years.
Treatment with the aromatase inhibitor letrozole (Femara) can reduce the risk of breast cancer recurrence even when initiated one to seven years after a course of tamoxifen therapy. The results of a study involving women originally in the placebo arm of an international trial of letrozole will appear in the Journal of Clinical Oncology and are receiving early online release. Among those who chose to begin letrozole treatment after the initial trial was halted, the risk that their cancer would recur was cut in half compared with those who never received letrozole. In addition, the risk of metastasis was 60 percent lower with letrozole, and the chance that a new tumor would develop in the unaffected breast dropped more than 80 percent.
The way proteins fold, and the good and bad effects of this molecular phenomenon, are what keeps biologist Susan L. Lindquist busy. Lindquist Ph.D. ’76, a Radcliffe Fellow this year, is an award-winning professor and researcher at the Massachusetts Institute of Technology (MIT) and a former director of the Whitehead Institute. She shared her insights on protein folding with an audience of 70 last week (March 5) at the fellowship program’s 34 Concord Ave. headquarters.
A panel of experts said Tuesday (March 11) that stem cell research’s biggest impact on patients’ health likely won’t come from therapies that inject stem cells or implant tissues made from them, but rather from the knowledge gained by examining diseased tissues grown from the cells.
A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week (March 12) in the Proceedings of the National Academy of Sciences (PNAS). The aerosol vaccine — under development through a collaboration between Harvard University and the international not-for-profit Medicine in Need (MEND) — could provide a low-cost, needle-free TB treatment that is highly stable at room temperature.
Mind-body medicine goes by many names today — including holistic, complementary, or alternative medicine. Regardless of what it’s called, many people embrace the ideas behind the mind-body connection and its effect on health, sometimes despite a lack of supporting scientific evidence. In her recently published book, “The Cure Within: A History of Mind-Body Medicine” (W.W. Norton and Company, 2008), Anne Harrington explores the long-lived and widespread belief in these unconventional medical practices.
With the careers of a generation of young researchers threatened by five years of flat National Institutes of Health (NIH) funding, Harvard President Drew Faust and leaders of six other major research institutions were in Washington Tuesday (March 11) calling on Congress to repair the “Broken Pipeline” through which breakthroughs in the biomedical sciences should be flowing.
Jeremy Jackson, renowned marine ecologist of the Scripps Institution of Oceanography, has been selected to receive the 11th annual Roger Tory Peterson Medal presented by the Harvard Museum of Natural History (HMNH). Jackson will deliver the Roger Tory Peterson Memorial Lecture on April 6 at 3 p.m. in the Science Center, 1 Oxford St.
Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes. The trial is exploring whether the promising results from the laboratory…
A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals…
The Harvard School of Public Health (HSPH) has announced the establishment of the A.G. Leventis Foundation Fellowship Program with a three-year grant to support Cypriot/Greek and Nigerian students and scholars in public health.
During her schooldays in 1950s Germany, Christiane Nüsslein-Volhard rarely did her homework. In 1995, she won the Nobel Prize for physiology and medicine. Volhard is now director of the prestigious Max Planck Institute for Developmental Biology in Tübingen, where, decades before, she had been an undistinguished biochemistry undergraduate. She was at Harvard this week (March 4) to deliver a talk sponsored by the Radcliffe Institute for Advanced Study as part of its Dean’s Lecture Series.
Massachusetts General Hospital (MGH) researchers — in collaboration with scientists at the University of California, San Diego, and Yale University — have discovered perhaps the strongest evidence yet linking variation in a particular gene with anxiety-related traits. In the March issue of Archives of General Psychiatry, the team describes finding that particular versions of a gene that affects the activity of important neurotransmitter receptors were more common in both children and adults assessed as being inhibited or introverted and also were associated with increased activity of brain regions involved in emotional processing.
J. Craig Venter, the visionary biologist and intellectual entrepreneur who was a leading figure in the decoding of the human genome, will join Harvard University as a visiting scholar at the University’s Origins of Life Initiative.
Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?
The first 30,000 pages of a massive online Encyclopedia of Life were unveiled last week at the Technology, Entertainment and Design (TED) conference in Monterey, Calif. The project was congratulated by E.O. Wilson, Pellegrino University Professor Emeritus, who articulated the need for a dynamic modern portrait of biodiversity in a widely read essay in 2003. “The launch of the Encyclopedia of Life will have a profound and creative effect in science,” Wilson said. “It aims not only to summarize all that we know of Earth’s life forms, but also to accelerate the discovery of the vast array that remain unknown.”
The Foundation for the History of Women in Medicine (FHWIM) is offering two fellowships to support research conducted at the Center for the History of Medicine and its Archives for Women in Medicine, located at Harvard Medical School’s Countway Library.
If a student is struggling, stressed-out, or having trouble coping with pressure, the University is here to listen and help. That’s the theme behind this year’s “Speak Out, Mental Health at Harvard,” a weeklong series of events to engage the student body in active campus dialogues about mental health.
Oleksiy Skrynnyk was just a carefree 9-year-old, his fishing rod slung over his shoulder as he walked home from his favorite pond. He never saw the low-hanging power line. Twenty-two hundred volts shot through his body, entering his right shoulder and exiting out his left foot. The electrocution burns were extensive. His right arm was so badly injured it had to be amputated. Though the level of care in Oleksiy’s homeland was what saved his life, his mother, Olga Zabolotina, knew her son needed more.
John M. Giurini, Chief of the Division of Podiatric Medicine and Surgery at Beth Israel Deaconess Medical Center and an Associate Professor in Surgery at Harvard Medical School was installed…
A new study led by researchers at the Joslin Diabetes Center has found that women with type 1 diabetes who reported taking less insulin than prescribed had a three-fold increased…
Manipulating levels of nitric oxide, a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy. …
Recently (Jan. 6-21), 15 Harvard and 16 Brazilian students participated in an intensive experience: the first Harvard-Brazil Collaborative Course on Infectious Diseases. The course, which was offered by the Harvard School of Public Health (HSPH) and the Santa Casa de Misericórdia de São Paulo Medical School (FCMSCSP) with the support of the Harvard University Brazil Studies Program at the David Rockefeller Center for Latin American Studies (DRCLAS), included lectures and informal discussions and visits to clinics, hospitals, laboratories, and community programs.
Researchers have identified a key reason why people make mistakes when they try to predict what they will like. When predicting how much they will enjoy a future experience, people tend to compare it to its alternatives — that is, to the experiences they had before, might have later, or could be having in the present moment. But when people actually have the experience, they tend not to think about these alternatives and their experience is relatively unaffected by them.
Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like state without the use of viruses or cancer-causing genes.
Shedding new light on the cognitive rift between humans and animals, a Harvard University scientist has synthesized four key differences in human and animal cognition into a hypothesis on what exactly differentiates human and animal thought.
During the course of the presidential nomination campaigns, some candidates’ health care plans have been described as “socialized medicine.” Historically, that phrase has been used to criticize health reform proposals in the United States.
Despite all the progress and promise of modern medicine, most of the world is still struggling to get the fundamentals of medical care: simple diagnostic tests, affordable medicines, and efficient…
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