Health
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New AI tool predicts brain age, dementia risk, cancer survival
Unlike other AI models, BrainIAC needs limited data to ID key neurological health indicators
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It’s time to get more comfortable with talking about dying
Palliative care physicians offer advice for end-of-life conversations between patients, loved ones
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Turns out inherited eye diseases aren’t a sure thing
Study finds only fraction of those with mutated gene develop malady — a finding that could lead to better treatments (and could apply to other such illnesses)
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How smoking divides America
Mapping the midlife effects of a lethal habit
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Americans living longer after cancer diagnosis
Oncologist explains why rising survival rates only tell part of the story
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Parental firearm injury linked to surge in children’s psychiatric diagnoses
Trauma/post-traumatic stress disorder accounts for most of the increase, according to study
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Gene clue to brain asymmetry revealed on right side
Although many assumed that the asymmetry-producing genes, when found, would be more highly expressed on the left side of the brain than the right, Sun Tao, Christopher A. Walsh, and…
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Fetal-cell transplants reverse Parkinson’s in two patients
The two patients were part of a small exploratory study in Halifax. In the study, the cells were bathed in the trophic factor GDNF before being implanted into the striatum,…
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Studies chip away at sex hormone roles in prostate and breast cancers
In recent work, Myles Brown and colleagues combined chromatin immunoprecipitation (ChiP) assays with measures of DNA structure and large-scale gene chip analyses to study where, when, and how androgen and…
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Novel combination overcomes drug-resistant multiple myeloma cells
The researchers hope to move rapidly to clinical trials of the therapy, a combination of the drug Velcade and an experimental compound that was designed by researchers at the Broad…
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CT significantly reduces the need for appendectomy
For the study, the researchers analyzed 663 patients who were examined on CT for suspected appendicitis. An appendectomy was performed on 268 of the CT-screened patients. Of these 268 patients,…
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‘Brown fat’ cells hold clues for possible obesity treatments
In laboratory studies of mouse cells, the research team identified genes that govern how precursor cells give rise to mature brown fat cells. There are two main types of fat…
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Exercise shown to promote breast cancer survival
Exercise plays a role in preventing breast cancer, and research strongly suggests that breast cancer patients who are more physically active improve their self-esteem and body image. Now, a landmark study from the Brigham and Women’s Hospital (BWH) finds that exercise after diagnosis may help breast cancer patients live longer.
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Imaging may not be major driver of hospital cost increases
“There have been several news stories and reports from insurers claiming that imaging costs are catching and even surpassing drug costs as major drivers of health care inflation,” says Scott…
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Magnetic stimulation may improve stroke recovery
Repetitive transcranial magnetic stimulation treatment improved motor function in a small group of people. For the stimulation, an insulated wire coil is placed on the scalp, and an electrical current…
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TB gene identified
As many as one out of three people in the world are infected with the bacteria that causes tuberculosis, public health experts estimate. That could lead to a global plague…
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Broken hearts may mend after all
Although adult muscle cells become inflexible after differentiation, these cells temporarily loosen the structure to divide in fetal development. Mark T. Keating found that in some lower vertebrates, heart tissue…
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Breathing restored after severe spinal-cord injury
Keeping an animal functioning after a cervical spinal cord injury is nearly impossible. An American researcher developed the lower spinal cord rat model in the early 1900s. He found that…
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Insulin prods development of type 1 diabetes
Joslin Diabetes Center researchers Diane Mathis’s and Christophe Benoist’s finding that the lymph node draining the pancreas was intrinsic to the autoimmune response in mice made David Hafler, HMS professor…
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Aspirin use may protect against colon cancer recurrence, reduce risk of death
“Our data are intriguing because they showed that aspirin use notably reduced the risk of recurrence in patients with advanced colon cancer, but more research is needed before any treatment…
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Drug combination boosts survival rate in head and neck cancers
Previous studies have shown that using combination chemotherapy of cisplatin and 5-fu yields a 25 to 50 percent rate of complete pathological responses (the tumor disappeared). Robert Haddad, M.D., and…
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Left- or right-brain? Genes may tell the story
According to HHMI investigator Christopher A. Walsh, postdoctoral fellow Tao Sun, and their colleagues at Beth Israel Deaconess Medical Center and Harvard Medical School, their discovery that a gene called…
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Brain chemical serotonin involved in early embryo patterning
A study published in the May 10, 2005, Current Biology has ramifications for neuroscience, developmental genetics, evolutionary biology and, possibly, human teratology (a branch of pathology and embryology concerned with…
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Study finds men who consume more dairy products have lower incidence of diabetes
A report from researchers at Massachusetts General Hospital (MGH), Harvard School of Public Health (HSPH) and Brigham and Women’s Hospital (BWH) – the first large-scale, prospective examination of a relationship…
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Low-fat dairy foods may help reduce risk of type 2 diabetes
“Our study found that men consuming higher levels of dairy products, especially low-fat dairy foods, had a significantly lower risk of developing type 2 diabetes during a 12-year period,” says…
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T cell misfits may spell autoimmunity
For a would-be T cell, the journey from cradle to grave is likely to be brief. After leaving the bone marrow, the immature immune cell travels directly to the thymus,…
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Antibiotics do not prevent heart attacks; New findings from the PROVE IT-TIMI 22 clinical trial
Christopher P. Cannon, M.D., of Brigham and Women’s Hospital and associate professor of medicine at Harvard Medical School, noted that the fact that many patients do not exhibit identifiable risk…
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Routine HIV screening recommended for most
Researchers at Harvard, Massachusetts General Hospital, and Yale University have shown that routine screening for HIV, the virus that causes AIDS, could increase survival, prevent transmission of the disease, and…
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TB susceptibility gene identified
As many as one out of three people in the world are infected with the bacteria that causes tuberculosis, public health experts estimate. That could lead to a global plague…
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Blood test can accurately diagnose heart failure in emergency patients
“We found that testing with the NT-proBNP assay was an extremely accurate way to identify or exclude heart failure in patients with shortness of breath,” says James Januzzi Jr., M.D.,…
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Stronger evidence found linking Epstein-Barr virus and risk of multiple sclerosis
Researchers from the Harvard School of Public Health, Kaiser Permanente, and a team of collaborators have found further evidence implicating the Epstein-Barr virus (EBV) as a possible contributory cause to…
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Spread of common day care illnesses caused by misconceptions about illness transmission
A Harvard Medical School study found that only two-thirds of parents believed that contact transmission was important for the spread of colds, and fewer than half believed it was important…
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Low-dose aspirin shown to reduce risk of first stroke in women
The Women’s Health Study is a large, randomized, double-blind, placebo-controlled trial funded by both the National Heart, Lung and Blood Institute and the National Cancer Institute to evaluate the benefits…
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MTV, Harvard Web study reveals adolescent disconnect: Unaware of hearing peril, yet willing to listen
While many adolescents and young adults expose themselves to loud music for entertainment, the researchers hypothesized that these individuals might not be aware that over-exposure could result in hearing loss.…
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New findings about protection against pneumococcal disease
Before the advent of the pneumococcal vaccine, known as Prevnar, S. pneumoniae caused millions of ear infections each year, half a million episodes of bacterial pneumonia, and life- threatening cases…
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Joslin Diabetes Center scientists find genetic defects in immunological tolerance
The genetic defect keeps the body from properly dealing with “errant” immune cells that it normally eliminates by a process called immunological tolerance. These immune cells then attack the insulin-producing…