Health
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Break in the case for long COVID investigators
Research highlighting chronic inflammation opens path to treating illness that affects millions of Americans
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The problem with the school smartphone debate
Study finds most districts already regulate devices. Is the real issue enforcement?
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Just who gets a say at FDA public drug-approval hearings?
New research shows negative voices are relatively rare in drug approval hearings.
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Your digital twin might save your life
AI, statistics offer new possibilities for personalized medicine
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Time to legalize psychedelics?
Campus debate weighs therapeutic need vs. safety questions
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How a toxin from the gut microbiome may help spark colorectal cancer
Findings suggest colibactin may be promising target for disease prevention
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Zoologist says in animal kingdom, less is more
Harvard researcher Piotr Naskrecki hopes his new book, “The Smaller Majority” (Harvard University Press, 2005), will win over some new advocates for the tiny creatures he has spent his life…
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Dietary fat intake linked to dry eye syndrome in women
Dry eye syndrome is characterized by a decline in the quality or quantity of tears that normally bathe the eye to keep it moist and functioning well. The condition causes…
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Herceptin treatment lowers recurrence rate in early breast cancer
Encouraging findings came from an interim report from HERA, an ongoing large, international clinical trial of Herceptin, published Oct. 19, 2005 in the New England Journal of Medicine. The analysis…
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Study finds vaccines boost the economies of poor countries
A study determined that previous measurements of the benefits of immunization have generally underestimated their economic value by focusing solely on health-related impacts such as averted illnesses, hospitalizations, deaths, disability,…
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Special delivery brings fats to immune system
It was both unexpected and unsurprising when, in the mid -1990s, Michael Brenner, the Theodore Bevier Bayles professor of medicine, and his colleagues showed that some antigen- presenting cells display…
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Vaccine may clear Alzheimer’s brain plaques
While there is still no consensus about the role of waxy amyloid plaques that fill the brains of Alzheimer’s patients, many in the field believe they are a root cause…
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Brain injury reversed in animal model of AIDS
Depending on the circumstances, missing N-acetylaspartate (NAA) in the brain may indicate Alzheimer’s disease, ischemic stroke, a brain tumor, or traumatic injury. And, as doctors soon learned with the AIDS…
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Ivory-billed woodpecker: Ornithology’s holy grail
Tim Gallagher and Bobby Harrison almost flopped into the mud of Arkansas’ Bayou de View in their haste to get out of the canoe. They crashed through the undergrowth after…
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Double trouble: Cells with duplicate genomes can trigger tumors
So-called “double-value” cells are produced by random errors in cell division that occur with unknown frequency. The generation of these genetically unstable cells appears to be a “pathway for generating…
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Stroke patients with mild symptoms may still need clot- dissolving drug
“Our primary finding was that about 30 percent of those patients judged ‘too good to treat’ either died or were discharged to a rehabilitation facility,” says Eric Smith, MD, FRCPC,…
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High blood glucose levels in early pregnancy may deprive embryo of oxygen
Research appearing in the October 2005 issue of the American Journal of Physiology: Endocrinology and Metabolism suggests that high blood glucose levels early in pregnancy deprive the embryo of oxygen,…
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Survey shows Harvard doctors practice what they preach
In the 30th anniversary year for the Harvard Health Letter, the editors decided to revive a tradition and ask Harvard doctors whether they follow their own advice – two similar…
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How ant (and human) societies might grow
Pellegrino University Professor Emeritus Edward O. Wilson remains fascinated with the highly organized societies of ants, bees, wasps, termites, and humans. He and Bert Holldobler, with whom he shared a…
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Health care reform in China discussed
Health care in the People’s Republic of China is unequal and too expensive, and there’s not enough of it, but the Chinese government is aware of the problems and is moving to address them, China’s vice minister of health said Sept. 8 at Harvard Medical School.
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Learning how the SARS virus spikes its quarry
Structural images that show how the SARS virus’s spike protein grasps its receptor may help scientists learn new details about how the virus infects cells and could also help in…
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Depression linked to previously unknown dopamine regulator
Li-Huei Tsai, Harvard Medical School (HMS) professor of pathology, HMS research fellow Sang Ki Park, and colleagues worked with mice and found a novel function for the molecule Par-4 (prostate…
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Critical step traced in anthrax infection
An anthrax bacterium secretes three nontoxic proteins that assemble into a toxic complex on the surface of the host cell to set off a chain of events leading to cell…
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Study identifies fat-secreted protein linked to insulin resistance
According to senior author Barbara B. Kahn, M.D., chief of the Division of Endocrinology, Diabetes, and Metabolism at BIDMC, these findings in mice and humans show that elevated levels of…
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Home from the hospital: almost half of patients are discharged with test results still pending
According to Christopher Roy, M.D., a hospitalist at BWH who studies patient safety, “We found that while approximately half of the patients in this study had test results that were…
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Bacterium proves essential to immune system development
In the July 15, 2005 Cell, a team led by Dennis Kasper, the William Ellery Channing Professor of Medicine at Brigham and Women’s Hospital and professor of microbiology and molecular…
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Molecular middleman puts thyroid hormone in developmental signaling pathway
Tissues such as muscle and brain convert the inactive form of thyroid hormone, T4, into T3, the active form of thyroid hormone, when necessary. In the 1980s, researchers discovered that…
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Subtle changes in normal genes implicated in breast cancer
Scientists found that benign cells surrounding breast cancers undergo epigenetic modifications. The altered gene function causes the microenvironment cells to signal proliferation and increased aggression in the breast tumor cells.…
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Study shows new compound may reduce risk of vision loss in patients with diabetes
The PKC-Diabetic Retinopathy Study (DRS) was designed to evaluate the safety and effect of an oral treatment, RBX, on retinopathy progression or visual loss in patients with moderately severe to…
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Blood vessel drugs halt cancer growth
After decades of surviving peer rejection of his theory of cancer treatment by blocking tiny blood vessels, Judah Folkman has gone on to develop drugs that did what he predicted…
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Size of brain structure could signal vulnerability to anxiety disorders
Individuals respond with physical and emotional distress to situations that recall traumatic memories. Such responses usually diminish gradually, as those situations are repeated without unpleasant occurrences; this is called “extinction…
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Women’s health study: Long-awaited findings of low-dose aspirin and vitamin E in preventing disease
The WHS trial was led by BWH researchers Nancy Cook, Sc.D., and Julie Buring, Sc.D. Its results are published in the July 6, 2005 Journal of the American Medical Association.…
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Scientists identify normal gene driving the growth and survival of melanoma cells
Dana-Farber’s Levi Garraway, M.D., Ph.D., and William Sellers, M.D., the paper’s first and senior authors, and their colleagues reported their findings in the July 7, 2005 issue of the journal…
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Urine test may help monitor disfiguring birthmarks
Vascular anomalies include both vascular malformations and vascular tumors (most commonly hemangiomas). Hemangiomas, found in about 10 percent of infants, occur when the cells lining blood vessels multiply abnormally. Hemangiomas…
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Child early intervention programs make for healthier adults
The Brookline Early Education Program (BEEP), a community- based child health and development program, was initiated by the Brookline Public Schools and the Robert Wood Johnson Foundation and ran from…
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DNA-scanning technology finds possible sites of cancer genes in chromosomes of lung cancer cell
In a study in the July 1, 2005 issue of the journal Cancer Research, the researchers used single nucleotide polymorphism (SNP) array technology to identify regions of chromosomes where genes…