Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.
Raphael Dolin of the Medical School discusses the evidence for hand washing, the timing of flu season, and who’s most vulnerable to serious complications.
The Bertarelli Program in Translational Neuroscience and Neuroengineering, a collaborative program between Harvard Medical School and the École Polytechnique Fédérale de Lausanne in Switzerland, has announced a new set of grants worth $3.6 million for five research projects.
New research illuminates the mixing with Neanderthals in early human prehistory, narrowing the window of time when they crossbred to between 50,000 and 60,000 years ago.
Harvard geneticist George Church discussed the future of genetic engineering, including possible technological applications allowing new treatment techniques. He saw the potential to improve human health, revolutionize pest management, and perhaps even bring back the mammoth and other extinct species.
Four scientists from across Harvard will receive nearly $8 million in grant funding through the National Institutes of Health’s High Risk-High Reward program to support research into a variety of biomedical questions, ranging from how the bacterial cell wall is constructed to how the blood-brain barrier works.
In a study reported in Nature Biotechnology, a team of Harvard scientists and engineers has developed a new surface coating for medical devices using materials already approved by the Food and Drug Administration (FDA). The researchers noted that the coating repelled blood from more than 20 medically relevant substrates (glass, plastic, and metal) and also suppressed biofilm formation.
Research led by Harvard investigators has found six new genes underlying coffee-drinking behavior.
Three nonprofits with strong Harvard ties have joined forces at the front lines of the Ebola epidemic in West Africa.
Six Harvard Medical School (HMS) researchers were among the recipients of the 2014 António Champalimaud Vision Award, the highest distinction in ...
New research from the lab of David Reich challenges the prevailing view among archaeologists that there were no major influxes of new peoples into Europe after the advent of agriculture.
Harvard researchers working at the Broad Institute of MIT and Harvard have uncovered nine rare genetic mutations that dramatically increase the risk of developing type 2 diabetes. The discovery of the mutations highlights the dizzying genetic diversity of a disease rapidly spreading around the world.
A new device inspired by the human spleen and developed by a team at Harvard’s Wyss Institute for Biologically Inspired Engineering may radically transform the way doctors treat sepsis.
The Harvard Program in Therapeutic Science has received $30 million in grant funding over the five years from three U.S. government agencies to launch its new research activities, Harvard Medical School announced on Sept. 11.
Harvard Humanitarian Initiative researchers polled residents of a war-torn part of the Democratic Republic of the Congo, finding that though many think the security situation has improved, trust in government is at a low ebb.
For 30 years, the Victims of Violence program at Harvard-affiliated Cambridge Health Alliance has been a force in trauma care.
Researchers at Harvard-affiliated McLean Hospital are reporting that xenon gas, used in humans for anesthesia and diagnostic imaging, has the potential to be a treatment for post-traumatic stress disorder (PTSD) and other memory-related disorders
The protective gear needed to get Sierra Leone’s health clinics reopened, coupled with public education about the Ebola epidemic, are the greatest areas of need, according to a Harvard Fulbright Fellow and physician from Sierra Leone.
Though the threat to the U.S. population from the Ebola outbreak in West Africa is low, the need in epidemic countries is great, says Michael VanRooyen, director of the Harvard Humanitarian Initiative.
To David Altshuler, the recent discovery of a genetic mutation that protects against type 2 diabetes offers hope in fighting more than just diabetes. It ...
A new technique for observing neural activity will allow scientists to stimulate neurons and observe their firing pattern in real time. Tracing those neural pathways can help researchers answer questions about how neural signals propagate, and could one day allow doctors to design individualized treatments for a host of disorders.
New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle that occurs in about half of all cancer patients, increasing their risk of death. Harvard Professor Bruce Spiegelman demonstrated that symptoms of cachexia in mice improved when given an antibody that blocked the effects of a protein secreted by the tumor cells.
A new study found that two-child families present five times more risk of sibling obesity than single-child homes with an obese parent, which doubles the risk. Obesity risk is even stronger among same-gender siblings.
Several Harvard students and alumni will work in some of Brazil’s most underserved communities this summer, helping change lives through soccer.
Will Lautzenheiser, a former Boston University film professor who lost his arms and legs from an infection, has been cleared by the Institutional Review Board at the Harvard-affiliated Brigham and Women’s Hospital for a double arm transplant, a complex procedure requiring 12 to 16 hours of work by a team of surgeons.
Nearly 400 sixth-, seventh-, and eighth-graders from 15 schools across Boston and Cambridge visited Harvard Medical School as part of the annual program Reflection in Action: Building Healthy Communities. The program works to expand students’ knowledge of health and public health issues.
A study from Harvard Medical School provides the first comprehensive description of how cytomegalovirus, or CMV, hijacks human cells and suggests entirely new ways to combat the infection.
A natural hormone that is increased by physical exercise and by exposure to cold improves blood sugar control, suppresses inflammation, and burns fat to mold leaner bodies in mice, report scientists at the Harvard-affiliated Dana-Farber Cancer Institute.
Divinity School graduate Shelley Brown is combining her love for science and religion to help stitch together two fields that rarely seem to meet.
Fraternal twins Rosh and Roshan Sethi have shared much of their lives, including at Yale as undergraduates and sharing an apartment while enrolled at Harvard Medical School. Now preparing to graduate, they’re anticipating diverging careers, with Roshan exploring radiation oncology and Rosh head and neck surgery.
Harvard scientists have merged stem cell and “organ-on-a-chip” technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular disease. The research appears to be a big step forward for personalized medicine, because it is working proof that a chunk of tissue containing a patient’s specific genetic disorder can be replicated in the laboratory.
Harvard researchers find that a gene essential for normal brain development, and linked to autism spectrum disorders, also plays a critical role in addiction-related behaviors.
A recent study by a group of Harvard-affiliated researchers found a sharp increase in the use of opioid painkillers among a large group of pregnant women between 2000 and 2007. Its lead author discussed the findings with the Gazette.
The Bertarelli Foundation of Switzerland, co-chaired by Ernesto Bertarelli, M.B.A. ’93, has established the Bertarelli Foundation Health and Life Sciences Entrepreneurship Fund with a gift to Harvard Business School.
Author and activist Eve Ensler, who opened Radcliffe’s two-day conference “Who Decides? Gender, Medicine, and the Public’s Health,” read from her new memoir, “In the Body of the World.” The conference brought together physicians, policymakers, journalists, and academics to examine topics such as how we care for our health and respond to disease.
Annual dinner honors Harvard staff who became U.S. citizens with help from the Harvard Bridge Program and the Harvard Kennedy School’s Institute of Politics.
Harvard stem cell scientists have discovered that a recently approved medication for epilepsy might be a meaningful treatment for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder.
Investigators at Harvard-affiliated Massachusetts General Hospital (MGH) may have found a way to solve a problem that has plagued ligand-mimicking integrin inhibitors, a group of drugs that have the potential to treat conditions ranging from heart attacks to cancer metastasis.
Harvard researchers have estimated that around 1 million children suffer from tuberculosis annually — twice the number previously thought to have the disease and three times the number of cases diagnosed every year.
Harvard University has announced 18 student-led teams as finalists in three deans’ innovation competitions focused on cultural entrepreneurship, health and life sciences, and design.
Harvard researchers have released the first study to show that the adverse effects of fried foods may vary depending on the genetic makeup of the individual.
Even the “healthy” fruit drinks that Americans sip are packed with the amount of sugar contained in six cookies. That love affair is making us sick.
Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University have discovered a way to build self-assembling cages made of DNA. The cages are the largest stand-alone DNA structures made to date, and one day may be able to deliver drugs or house tiny bioreactors or photonic devices inside the human body.
A novel approach to cancer immunotherapy — strategies designed to induce the immune system to attack cancer cells — may provide a new and cost-effective weapon against some of the most deadly tumors, including ovarian cancer and mesothelioma.
Researchers at the Broad Institute and Massachusetts General Hospital, both Harvard affiliates, have identified mutations in a gene that can reduce the risk of individuals developing type 2 diabetes. If a drug can be developed that mimics the protective effect of these mutations, it could open up new ways of preventing this devastating disease.
The first clinical trial of a drug intended to delay the onset of symptoms of Huntington’s disease (HD) reveals that high-dose treatment with the nutritional supplement creatine was safe and well tolerated by most study participants. Neuroimaging also showed a treatment-associated slowing of regional brain atrophy, evidence that creatine might slow the progression of presymptomatic HD.
Syrian refugees struggling in Lebanon are on the edge of catastrophe, according to a new report from the FXB Center for Health and Human Rights.
Harvard’s Wyss Institute has found a new DNA-based, super-resolution microscopy method that could simultaneously spot dozens of distinct types of biomolecules. This could potentially lead to new ways to diagnose disease, track its prognosis, or monitor the effectiveness of therapies at a cellular level.
Remnants of Neanderthal DNA in modern humans are associated with genes affecting type 2 diabetes, Crohn’s disease, lupus, biliary cirrhosis, and smoking behavior. They also concentrate in genes that influence skin and hair characteristics. At the same time, Neanderthal DNA is conspicuously low in regions of the X chromosome and testes-specific genes.
Researchers have created embryonic stem cells without an embryo. This discovery of a novel reprogramming method of adult cells, without introducing external genetic material, could dramatically shift stem cell research.