A new technique for observing neural activity will allow scientists to stimulate neurons and observe their firing pattern in real time. Tracing those neural pathways can help researchers answer questions about how neural signals propagate, and could one day allow doctors to design individualized treatments for a host of disorders.
A new theoretical framework outlined by a Harvard scientist could help solve the mystery of how bacterial cells coordinate processes that are critical to cellular division, such as DNA replication, and how bacteria know when to divide.
A team at Harvard Stem Cell Institute recently found that transplanting mesenchymal stem cells along with blood-vessel-forming cells naturally found in circulation improves results. This co-transplantation keeps the mesenchymal stem cells alive longer in mice after engraftment, up to a few weeks compared with hours without co-transplantation.
Harvard Stem Cell Institute scientists collaborating with researchers at the University of Pennsylvania have developed a “genome-editing” approach for permanently reducing cholesterol levels in mice through a single injection, a development with the potential to reduce the risk of heart attacks in humans by 40 to 90 percent.
A team of Harvard researchers has demonstrated that a shared developmental mechanism in songbirds is responsible for generating tremendous variability in their beaks, and is also a control on what kind variation can be produced.
A study from Harvard Medical School provides the first comprehensive description of how cytomegalovirus, or CMV, hijacks human cells and suggests entirely new ways to combat the infection.
A natural hormone that is increased by physical exercise and by exposure to cold improves blood sugar control, suppresses inflammation, and burns fat to mold leaner bodies in mice, report scientists at the Harvard-affiliated Dana-Farber Cancer Institute.
Divinity School graduate Shelley Brown is combining her love for science and religion to help stitch together two fields that rarely seem to meet.
The Harvard Stem Cell Institute is now 10 years old. What began as an idea embracing cross-disciplinary research quickly became a generator of scientific discoveries.
It could be that the key to being a better parent is all in your head, Harvard researchers say.
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Harvard scientists have merged stem cell and “organ-on-a-chip” technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular disease. The research appears to be a big step forward for personalized medicine, because it is working proof that a chunk of tissue containing a patient’s specific genetic disorder can be replicated in the laboratory.
Despite this year’s long winter and slow-warming spring, Harvard experts say that climate change hasn’t gone on hiatus. Long-term evidence indicates that spring in Boston has begun coming weeks earlier over the last century. The Gazette spoke with Elizabeth Wolkovich, a recently appointed assistant professor of organismic and evolutionary biology, about spring’s arrival, climate change, and nature’s life cycles.
Harvard Stem Cell Institute researchers at Boston Children’s Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells have the functional hallmarks of HSCs and are able to self-renew like those cells.
For most people, rock-paper-scissors is a game used to settle disputes on the playground. For biologists, however, it is a powerful guide for understanding ...
A study following more than 1,800 children from ages 6 months to nearly 8 years old found a small but consistent association between increased television viewing and shorter sleep duration.
New research conducted at Harvard demonstrates sharing behavior in African grey parrots.
The narwhal tusk has now been mapped, showing a pathway between the spiral tooth and the narwhal brain. The study reflects how the mysterious animal may use its tusk to suss out its environment.
Scientists have long suggested that the best way to settle the debate about how phenotypic plasticity may be connected to evolution would be to identify a mechanism that controls both. Harvard researchers say they have discovered just such a mechanism in insulin signaling in fruit flies.
A Harvard research team led by Kevin Kit Parker, a Harvard Stem Cell Institute principal faculty member, has identified a set of 64 crucial parameters by which to judge stem cell-derived cardiac myocytes, making it possible for scientists and pharmaceutical companies to quantitatively judge and compare the value of stem cells.
Harvard stem cell scientists have successfully converted skins cells from patients with early onset Alzheimer’s into the types of neurons affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells.