Tag: Yujiang Shi
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Health
Protein reverses engineering of chromosome structure
An enzyme, a histone demethylase, removes methyl groups appended to histones, nuclear proteins that organize DNA and regulate gene activity. Methyl groups and other chemical tags on histones regulate how the DNA wraps around the proteins to form a chromatin structure that either promotes gene activity or represses it. Chromatin, which contains DNA, RNA, and…