Tag: Work in Progress
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Nation & World
Researchers explain how protein inhibits growth of blood vessels
Thirty years ago, Judah Folkman, of Children’s Hospital Boston and Harvard Medical School, first developed the idea that cancerous tumors are dependent on the growth of small blood vessels. Since…
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Nation & World
Study upends earlier thinking about immune cell’s readiness against disease
A type of disease-fighting cells in the body — T cells — have a reputation for being ever-ready to fight invading infections. But that’s not the way they really work,…
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Nation & World
Study reveals how child abuse can lead to substance abuse
It’s a common-sense notion that those who have been abused as children may became drug abusers later in life. But why is this so? Carl Anderson, a Harvard instructor in…
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Nation & World
Study finds embryonic stem cells can repair heart muscle
Heart failure develops when the heart stops pumping effectively due to the destruction of muscle cells, known as cardiomyocytes. Damage inflicted during a heart attack causes massive loss of cardiomyocytes,…
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Nation & World
High levels of Epstein-Barr virus antibodies in women linked to risk of multiple sclerosis
Multiple sclerosis is a chronic degenerative disease of the central nervous system. Nationwide, there are an estimated 250,000 to 350,000 people with MS. Researchers have long wondered how MS develops…
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Nation & World
User fees have unintended effect of decreasing health care access for poor
The reform of health care systems is supposed to make access to health care better. But in the particular case of user fees, the opposite effect was observed. During the…
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Nation & World
Grants vs . investment subsidies
In many countries, governments face policy decisions about how to help poor people who have difficulty helping themselves because they can’t borrow money. What is the proper form of intervention?…
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Nation & World
Pain and pleasure activate same brain structures
David Borsook is a Harvard Medical School associate professor of radiology, who both treats patients and conducts research. “Over 15 years of seeing patients with pain it became obvious that…
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Nation & World
Diagnosis by database shows promise
A relatively new approach to researching cancer involves looking at the actions of thousands of genes in cancer tumors. This technique just recently became possible because, using new applications of…
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Nation & World
Sickle cell disease cured in mouse model
Sickle cell disease is a blood disorder caused by a single mutation in the beta-globin gene that results in the substitution of one amino acid. This small error is enough…
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Nation & World
Technique enables quick accounting of gene function
Now that whole genomes have been sequenced, a group of scientists has geared up for the next phase: identification and classification of newly discovered coding regions. The DNA microchip, developed…
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Nation & World
Polarity gene yields clues to organization of cell signaling, structural growth
Researchers are beginning to understand how a gene called “stardust” works to set up the basic top-down architecture of the epithelial cells that line the gut, skin, and many other…
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Nation & World
Lithium drugs found to reduce suicide risk
Researchers who wondered about the effectiveness of lithium drugs in treating patients with severe depression analyzed 22 studies involving 5,647 patients. The scientists, working at Harvard-affiliated McLean Hospital in Belmont,…
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Nation & World
Looking toward the end
Among astronomers there is almost a consensus that universal expansion will go on forever, with galaxies and clusters of galaxies moving away from each other so fast that gravity cannot…
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Nation & World
Scientists using gene chips identify unique form of leukemia
Currently, physicians diagnose and treat a rare form of cancer that strikes infants as a particularly aggressive form of the more common acute lymphoblastic leukemia. The cancer may respond to…
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Nation & World
Early exposure to Ritalin may blunt desire for cocaine later in life
There are several controversies surrounding the use of Ritalin, or methylphenidate, a stimulant prescribed for children who have an abnormally high level of activity or attention deficit hyperactivity disorder (ADHD).…
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Nation & World
Analysis of potential mad cow risk in U.S. finds little chance of disease spread
The Harvard Center for Risk Analysis (HCRA), part of the Harvard School of Public Health, performed an analysis for the U.S. Department of Agriculture to determine what the effects would…
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Nation & World
Comprehensive set of vision genes discovered
Using a computer program that compares bits of genetic material taken from tissue in the retinas of mice against records in a huge genetic data base from the mouse and…
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Nation & World
Whole genes delivered to cells
To make a protein, a cell’s enzymes typically edit out about 90 percent of the information along the length of a DNA strand that makes up a whole gene. In…
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Nation & World
“Commoner” in brain crowns the cortex
With its role in higher cognitive functions, the cortex represents a significant evolutionary development in mammals, culminating in the enlarged hemispheres of humans and other primates. In the development of…
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Nation & World
The fruit fly fight club
Fruit flies fight. The males will go after each other, fighting to establish dominance. Edward Kravitz, the George Packer Berry professor of neurobiology at Harvard Medical School, is using the…
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Nation & World
New study provides mixed report card on informed consent to cancer clinical trials
According to a study that appeared in the Nov. 24, 2001, issue of The Lancet, nearly one quarter of cancer patients who participate in clinical trials do not realize that…
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Nation & World
Research suggests optimistic attitude can reduce risk of heart disease in older men
Researchers from the Harvard School of Public Health, working with colleagues from the Department of Veterans Affairs, studied some 1,306 Boston area men who were part of the Veterans Affairs…
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Nation & World
Immune system discovery may lead to preventive therapy for diabetes
The job of cells known as iNKT cells is to regulate the immune system’s response to infections and other disorders, ensuring that only diseased tissue, not healthy tissue, is targeted…
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Nation & World
Cell protein potently blocks enzyme linked to cancer
The ends of chromosomes in normal cells eventually unravel, causing the cells to die. This does not happen in cancer cells, however. Cancer cells use an enzyme named telomerase to…
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Nation & World
Dopamine may play dual role in Parkinson’s disease
According to the Parkinson’s Disease Foundation, “Parkinson’s disease (PD) is a disorder of the central nervous system that affects between one and one-and-a-half million Americans. Because it is not contagious…
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Nation & World
“Heart of glass” may be more than just a metaphor
Jeffrey Fredberg is a professor of bioengineering and physiology at the Harvard School of Public Health. His primary research interest is asthma. Fredberg was intrigued by the plasticity of the…
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Nation & World
Anthrax expert Matthew Meselson speaks out
In 1992-93, Harvard Professor Matthew Meselson investigated the largest known outbreak of inhalation anthrax in history, which occurred in the Soviet Union in 1979. The anthrax was accidentally released from…