Tag: James Bradner

  • Health

    Developing cancer drugs

    Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

    3–5 minutes
  • Health

    Researchers ‘NOTCH’ a victory in war on cancer

    Normal 0 0 1 819 4673 38 9 5738 11.1282 0 0 0 Scientists have devised an innovative way to disarm a key protein considered to be “undruggable,” meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in today’s edition of the journal Nature, lays the foundation for…

    4–6 minutes
  • Health

    Novel combination overcomes drug-resistant multiple myeloma cells

    The researchers hope to move rapidly to clinical trials of the therapy, a combination of the drug Velcade and an experimental compound that was designed by researchers at the Broad Institute of the Massachusetts Institute of Technology and Harvard University. The report demonstrates that the combination was more than twice as effective as either drug…

    1–2 minutes