Researchers from the lab of Joan Brugge, Harvard Medical School professor of cell biology, may have uncovered one of the central mechanisms of breast cancer. They found that dual signals…
A gene that builds bigger brains, called beta-catenin, was discovered in the laboratory of Christopher A. Walsh, Bullard Professor of Neurology at Harvard Medical School. Researchers there engineered increased activity…
Malaria is the world’s most serious parasitic tropical disease and kills more people than any communicable disease except for tuberculosis. There is more human malaria in Africa today than at…
A study involved seeding cells from the immature teeth of six-month old pigs onto biodegradable polymer scaffolds. The researchers then placed these structures into rat hosts. Within 30 weeks, small,…
A new system developed by Harvard undergraduates delivers anti-tuberculosis drugs through an inhaler, increasing the likelihood that patients will take them over longer periods, and reducing the side effects of…
Researchers have discovered that the burinng pain of arthritis is similar to the pain associated with eating chili peppers. “The receptor activated by chili peppers in the mouth and other…
In the cover article of the September 2002 issue of the journal Cancer Cell, researchers from Dana-Farber Cancer Institute reported that peptide subunits of cell-signaling “BH3” proteins could out-maneuver opposing…
In many regions of Africa, between 15 and 30 percent of women attending prenatal care clinics are HIV-1 positive. And 20 to 45 percent of children born to HIV-1 positive…
The cytoskeleton is made up of arrays of actin filaments that are arranged into widely different structures — parallel arrays that mediate muscle contraction, networks of branched filaments at the…
Julia Ying Wang, a Harvard Medical School assistant professor of medicine at Brigham and Women’s Hospital, was exploring whether a particular class of carbohydrates called glycosaminoglycans (GAGs) trigger an immune…
A research report that appears in the September 2002 issue of the journal Archives of Neurology may improve understanding of the most common form of Alzheimer’s disease. “Our key finding…
IGF-1 is a hormone important to the growth and function of many organs. Higher levels of IGF-1 have been associated independently with an increased risk of a number of cancers,…
An experimental drug called defibrotide reversed severe veno-occlusive disease (VOD) of the liver in more than one third of the stem cell transplant recipients enrolled in a study. VOD is…
Recent studies have gathered evidence that cat exposure during infancy can be protective against asthma. Research at Brigham and Women’s Hospital confirmed these findings in all but one situation: when…
In the body, dendritic and other antigen-presenting cells initially handle all infections in the body. The dendritic cells lurk in the skin, lungs, gut, and other tissues. On sentry duty,…
The drug Gleevec was stunningly successful in treating patients with chronic myelogenous leukemia (CML) at early stages of disease, but quickly stopped working in most patients with more advanced forms…
Since nerve cell axons in the mature central nervous system do not regrow, neurologists have no way of fully treating paralysis due to injury. “About a hundred years ago, people…
Megan Sykes, head of the bone marrow transplantation section of the Massachusetts Transplantation Biology Research Center and professor of surgery at Harvard Medical School, recently described how infusing kidney transplant…
Your mouth is a great place for micropests to dwell. Glistening white plateaus, dark crevices, and slimy surfaces boast steamy temperatures of 95 degrees Fahrenheit. The microbes bathe in a…
Published in the Aug. 15, 2002 issue of the journal Nature, findings from a multi-institutional team describe the pivotal role of a molecule called PGC-1 in transforming “fast twitch” fibers…
Heart attacks and strokes are caused by blood clots called thrombi that block blood flow in the arteries of the heart and of the brain. Body tissues become deprived of…
What determines whether excess calories are turned into fat or are burned off? The key lies in a process known as diet-induced thermogenesis, an intricate system of communications masterminded by…
Five years ago, scientists at Harvard University began to take a close look at Copolymer 1, a treatment for multiple sclerosis, that is put together from a string of amino…
Type II diabetes accounts for the majority of cases of the disease, and is a huge public health problem: As many as 16 million individuals in the United States have…
Harvard Medical School researchers conducted a study in which people were taught to type a sequence of keys on a computer keyboard as quickly and accurately as possible. A group…
The immediate goal of the treatment of heart attack patients is reperfusion, or the swift opening of the blocked artery and the restoration of blood flow to the heart muscle.…
Although much attention has been paid to public health efforts to reduce lead exposure in children between the ages of six months and five years, when environmental lead exposures (such…
For years, physicians have prescribed antiretroviral therapies for HIV-positive, pregnant women to reduce the risk of babies being born with the AIDS virus. About 6,000 HIV-infected women give birth each…
After a stroke, brain cells die and their connections to other parts of the brain are lost. In a study with rats conducted at Children’s Hospital in Boston, a naturally…
Metastasis occurs when cancer cells penetrate the boundaries of the tumor’s tissue and infiltrate the walls of blood vessels or lymph vessels, gaining a means of transport to other parts…
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