2 stories tagged ‘James Bradner’
Researchers ‘NOTCH’ a victory in war on cancer
Scientists have devised an innovative way to disarm a key protein considered to be “undruggable,” meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in today’s edition of the journal Nature, lays the foundation for a new therapy aimed directly at a critical human protein — one of [...]
Novel combination overcomes drug-resistant multiple myeloma cells
The researchers hope to move rapidly to clinical trials of the therapy, a combination of the drug Velcade and an experimental compound that was designed by researchers at the Broad Institute of the Massachusetts Institute of Technology and Harvard University. The report demonstrates that the combination was more than twice as effective as either drug [...]
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