Featured series 
Tag: David M. Altshuler
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Nation & World
International study identifies gene variants associated with early heart attack
The largest study ever completed of genetic factors associated with heart attacks has identified nine genetic regions — three not previously described — that appear to increase the risk for early-onset myocardial infarction. The report from the Myocardial Infarction Genetics Consortium, based on information from a total of 26,000 individuals in 10 countries, was given…
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Nation & World
Database of human genetic diversity allows identification of disease-associated genes
Investigators from six countries have completed the second phase of the International HapMap Project, an effort to identify and catalog genetic similarities and differences among populations around the world. Information…
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Nation & World
HapMap reveals roots of common diseases
The genes that everyone inherits contain coded information that influences which diseases any individual is most at risk of getting. Countless studies show that small variations in genes play a…
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Nation & World
HapMap: First look at ‘order in variety’ of human genome
The completion of the human genome sequence in 2003, though momentous, was only the first step toward grasping the core mechanisms of human biology and disease. This ultimate biomedical goal…
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Nation & World
First edition of HapMap released
A flurry of high-profile scientific manuscripts published in October 2005 describe both the content and uses of HapMap, a catalog that maps human genetic variation and relates it both to…
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Nation & World
The next big thing in mining the genome
About 99.9 percent of the 3.1 billion base pairs in the human genome are the same from person to person. The remaining 0.1 percent of differences comprises more than 10…