Health
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How HIV research has reshaped modern medicine
Decades of scientific work turned the tide on a fatal disease and yielded insights into immunity, vaccines, and more
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Use of new diet drugs likely to mushroom
Study estimates over half of Americans eligible to take them based on conditions, underscoring need to ensure equity of access.
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Rapid relief for the severely depressed? There’s a catch.
Ketamine carries risks, say researchers. Yet for some patients, it’s ‘the only thing that works.’
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New frontiers in cancer care
In podcast, experts discuss breakthroughs in treatment, from genomic sequencing to AI, and how close we are to personalized vaccines
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Too much sitting hurts the heart
Even with exercise, sedentary behavior can increase risk of heart failure by up to 60%, according to study
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Is cheese bad for you?
Nutritionist explains why you’re probably eating way too much
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Study says women don’t experience pain, anxiety during mammograms
“I think it’s an old wives tale that mammograms hurt,” says the study’s lead author, Alice Domar, PhD, director of the Mind/ Body Center for Women’s Health at Boston IVF…
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Snaring secrets of the Venus flytrap
While “speed” is not a word most people associate with the plant kingdom, the Venus flytrap closes its v-shaped leaves in just one-tenth of a second – fast enough to…
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Weight gain and obesity linked to higher risk of kidney stones
“Our study demonstrated that multiple measures of larger body size, including larger waist circumference, higher weight, and higher body mass index, were related to an elevated risk of kidney stones,”…
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Solving the mystery of a centuries-old plague
Edward O. Wilson identified two different ant species in investigating the mystery of centuries-old plagues, a tropical fire ant in the early 1500s and an introduced African ant in the…
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Safer cigarettes would cut fire deaths if made available
Researchers at Harvard School of Public Health, funded by the American Legacy Foundation, compared the physical properties of cigarettes sold in New York with cigarettes of the same brands sold…
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First view of many neurons processing information in living brain
A Harvard Medical School (HMS) research team used a new technique to obtain the first close-up look at the neural circuits that produce vision in cats and rats. “Put simply,…
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One alcoholic drink per day improves cognitive function among older women
According to the study’s senior author, BWH’s Francine Grodstein, Sc.D., “Much evidence has demonstrated the heart benefits of light alcohol drinking, but less research has focused on cognitive functioning. While…
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Monitoring system needed to prevent safety hazard of problem physicians
Asserting that “physician performance failures are not rare and pose substantial threats to patient welfare and safety,” experts in medical error are calling on state medical boards and healthcare organizations…
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Findings recommend herpes vaccine for human trials
Research published in the January 2005 Journal of Virology compared three different experimental vaccines for herpes simplex virus 2 (HSV-2), which causes most cases of genital herpes. Lead author Stephen…
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Disparate proteins structurally identical
Gerhard Wagner, the Elkan Blout professor of biological chemistry and molecular pharmacology, and Tucker Collins, the S. Burt Wolbach professor of pathology at Harvard Medical School and Children’s Hospital, made…
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RNA-making apparatus seen to uncoil and recoil DNA
Eukaryotic cells like to keep their DNA under wraps, winding the long strands of nucleic acid around millions of little protein complexes. This bead-on-a-string structure, called chromatin, ensures that the…
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One third of U.S. adults use complementary and alternative medicines
The continued widespread use of individual and multiple CAM therapies underscores the need to rigorously evaluate the safety, efficacy, and cost-effectiveness of these approaches, according to the study’s lead author…
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Protein in urine may warn of preeclampsia risk in pregnant women
Preeclampsia, or toxemia, develops during pregnancy. In severe cases, it can rapidly escalate to eclampsia, a condition in which the mother suffers a series of potentially fatal complications. Ananth Karumanchi,…
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Researchers discover why we go gray
People turn gray, Harvard scientists found, when certain adult stem cells gradually die off. The stem cells provide a continuous supply of other, pigment-producing cells that give your hair its…
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Anti-psychotic drugs may be associated with increased risk of diabetes in schizophrenia patients
According to the article’s background information, “Recently, the newer ‘atypical’ antipsychotic agents have been linked to several forms of morbidity, including obesity; hyperlipidemia; type 2 diabetes mellitus; and diabetic ketoacidosis…
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Study finds heavy drinking linked to higher stroke risk
A study found that while light and moderate drinkers appear to be at neither greater risk nor greater advantage than abstainers when it comes to ischemic stroke, the frequency of…
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Researchers identify gene’s role in suppressing longevity
SIRT1 is involved in cellular senescence, or limitation of cells’ reproductive lifespan, a process thought to ensure that aging cells don’t pass on harmful mutations. Frederick W. Alt, a Howard…
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Extended release stimulant effective for long-term ADHD treatment
In the October 2005 issue of the Journal of the American Association of Child and Adolescent Psychiatry, a multi- institutional research team reported finding that treatment with Concerta, a once-daily…
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Researchers find a gene for fear
A team of researchers from Harvard, Columbia, and Rutgers universities has found the seat of fear. It’s located in a pea-sized area deep in the brain of all mammals, from…
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Study casts doubt on claims that the medical malpractice system is plagued by frivolous lawsuits
The debate over medical malpractice litigation, which raged during the last presidential campaign, continues as a hot-button political and health care issue in the U.S. The Senate is expected to…
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Study suggests obesity has lesser financial impact on African-Americans
The study published in the January 2005 issue of the American Journal of Public Health is among the first to examine how patient demographic factors affect the relationship between body…
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Faulty gene signaling could lead to development of Crohn’s disease
According to the study’s lead author, Brigham Women’s Hospital’s Derek W. Abbott, “The discovery of this faulty signaling process is a first step in helping us understand and ultimately address the underlying mechanism that causes Crohn’s disease to develop.
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Study finds that both weight and exercise are key to longevity
Over 115,000 participants who were free of cardiovascular disease or cancer, who were between the ages of 30 and 55 and had filled out biennial health and lifestyle questionnaires between…
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Molecule implicated in transcription termination
When a protein is made its DNA code must first be rewritten as messenger RNA (mRNA). This process of transcription requires a large enzyme complex, RNA polymerase, to begin at…
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DNA splicing enzyme observed in action
Researchers in the lab of Tom Ellenberger, the Hsien Wu and Daisy Yen Wu professor of biological chemistry and molecular pharmacology at Harvard Medical School, reported the doughnut shape of…
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Protein reverses engineering of chromosome structure
An enzyme, a histone demethylase, removes methyl groups appended to histones, nuclear proteins that organize DNA and regulate gene activity. Methyl groups and other chemical tags on histones regulate how…
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Researchers find high levels of potentially toxic heavy metals in herbal medicine products
“This study, yet again, highlights the need for Congress to revisit the way dietary supplements are regulated in the U.S.,” said co- author David Eisenberg, MD, the Bernard Osher Associate…
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Study finds women hesitant to take tamoxifen as preventive measure
“Our study underscores the need [for medical professionals] to address psychological factors that may influence decision- making, in order to help women feel confident and satisfied with their treatment choice,”…
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Accumulated low-level lead exposure can lead to cataract development in men
According to lead author Debra A. Schaumberg, Sc.D., O.D., M.P.H. of BWH, “This research suggests that reduction of lead exposure throughout a man’s lifetime should help reduce his chances of…
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Sudden death among military personnel often caused by exercise and an identifiable cardiac abnormality
According to the study’s lead author BWH’s Robert E. Eckart, D.O., they had expected that most of the sudden deaths would stem from structural heart abnormalities, but that in actuality,…