“Our primary finding was that about 30 percent of those patients judged ‘too good to treat’ either died or were discharged to a rehabilitation facility,” says Eric Smith, MD, FRCPC,…
Research appearing in the October 2005 issue of the American Journal of Physiology: Endocrinology and Metabolism suggests that high blood glucose levels early in pregnancy deprive the embryo of oxygen,…
In the 30th anniversary year for the Harvard Health Letter, the editors decided to revive a tradition and ask Harvard doctors whether they follow their own advice – two similar…
Pellegrino University Professor Emeritus Edward O. Wilson remains fascinated with the highly organized societies of ants, bees, wasps, termites, and humans. He and Bert Holldobler, with whom he shared a…
Health care in the People’s Republic of China is unequal and too expensive, and there’s not enough of it, but the Chinese government is aware of the problems and is moving to address them, China’s vice minister of health said Sept. 8 at Harvard Medical School.
Structural images that show how the SARS virus’s spike protein grasps its receptor may help scientists learn new details about how the virus infects cells and could also help in…
Li-Huei Tsai, Harvard Medical School (HMS) professor of pathology, HMS research fellow Sang Ki Park, and colleagues worked with mice and found a novel function for the molecule Par-4 (prostate…
An anthrax bacterium secretes three nontoxic proteins that assemble into a toxic complex on the surface of the host cell to set off a chain of events leading to cell…
According to senior author Barbara B. Kahn, M.D., chief of the Division of Endocrinology, Diabetes, and Metabolism at BIDMC, these findings in mice and humans show that elevated levels of…
According to Christopher Roy, M.D., a hospitalist at BWH who studies patient safety, “We found that while approximately half of the patients in this study had test results that were…
In the July 15, 2005 Cell, a team led by Dennis Kasper, the William Ellery Channing Professor of Medicine at Brigham and Women’s Hospital and professor of microbiology and molecular…
Tissues such as muscle and brain convert the inactive form of thyroid hormone, T4, into T3, the active form of thyroid hormone, when necessary. In the 1980s, researchers discovered that…
Scientists found that benign cells surrounding breast cancers undergo epigenetic modifications. The altered gene function causes the microenvironment cells to signal proliferation and increased aggression in the breast tumor cells.…
The PKC-Diabetic Retinopathy Study (DRS) was designed to evaluate the safety and effect of an oral treatment, RBX, on retinopathy progression or visual loss in patients with moderately severe to…
After decades of surviving peer rejection of his theory of cancer treatment by blocking tiny blood vessels, Judah Folkman has gone on to develop drugs that did what he predicted…
Individuals respond with physical and emotional distress to situations that recall traumatic memories. Such responses usually diminish gradually, as those situations are repeated without unpleasant occurrences; this is called “extinction…
The WHS trial was led by BWH researchers Nancy Cook, Sc.D., and Julie Buring, Sc.D. Its results are published in the July 6, 2005 Journal of the American Medical Association.…
Dana-Farber’s Levi Garraway, M.D., Ph.D., and William Sellers, M.D., the paper’s first and senior authors, and their colleagues reported their findings in the July 7, 2005 issue of the journal…
Vascular anomalies include both vascular malformations and vascular tumors (most commonly hemangiomas). Hemangiomas, found in about 10 percent of infants, occur when the cells lining blood vessels multiply abnormally. Hemangiomas…
The Brookline Early Education Program (BEEP), a community- based child health and development program, was initiated by the Brookline Public Schools and the Robert Wood Johnson Foundation and ran from…
In a study in the July 1, 2005 issue of the journal Cancer Research, the researchers used single nucleotide polymorphism (SNP) array technology to identify regions of chromosomes where genes…
Researchers led by Johanna M. Seddon, M.D., at the Massachusetts Eye and Ear Infirmary, Harvard Medical School, and Harvard School of Public Health, conducted a prospective longitudinal study to examine…
Three years later, Joseph Arboleda-Velasquez, an HMS graduate student who led the scientific team that identified the mutations, and his collaborators have worked out an early step in the events…
Although many assumed that the asymmetry-producing genes, when found, would be more highly expressed on the left side of the brain than the right, Sun Tao, Christopher A. Walsh, and…
The two patients were part of a small exploratory study in Halifax. In the study, the cells were bathed in the trophic factor GDNF before being implanted into the striatum,…
In recent work, Myles Brown and colleagues combined chromatin immunoprecipitation (ChiP) assays with measures of DNA structure and large-scale gene chip analyses to study where, when, and how androgen and…
The researchers hope to move rapidly to clinical trials of the therapy, a combination of the drug Velcade and an experimental compound that was designed by researchers at the Broad…
For the study, the researchers analyzed 663 patients who were examined on CT for suspected appendicitis. An appendectomy was performed on 268 of the CT-screened patients. Of these 268 patients,…
In laboratory studies of mouse cells, the research team identified genes that govern how precursor cells give rise to mature brown fat cells. There are two main types of fat…
Exercise plays a role in preventing breast cancer, and research strongly suggests that breast cancer patients who are more physically active improve their self-esteem and body image. Now, a landmark study from the Brigham and Women’s Hospital (BWH) finds that exercise after diagnosis may help breast cancer patients live longer.
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