Health
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How HIV research has reshaped modern medicine
Decades of scientific work turned the tide on a fatal disease and yielded insights into immunity, vaccines, and more
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Use of new diet drugs likely to mushroom
Study estimates over half of Americans eligible to take them based on conditions, underscoring need to ensure equity of access.
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Rapid relief for the severely depressed? There’s a catch.
Ketamine carries risks, say researchers. Yet for some patients, it’s ‘the only thing that works.’
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New frontiers in cancer care
In podcast, experts discuss breakthroughs in treatment, from genomic sequencing to AI, and how close we are to personalized vaccines
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Too much sitting hurts the heart
Even with exercise, sedentary behavior can increase risk of heart failure by up to 60%, according to study
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Is cheese bad for you?
Nutritionist explains why you’re probably eating way too much
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Binge eating disorder may have genetic ties
Researchers at Harvard-affiliated McLean Hospital have reported that binge eating disorder runs in families, raising the possibility that this condition may have a genetic basis. In the study, published in…
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Study provides first physiological evidence that insulin is critical for blood vessel formation
For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with…
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How gold and other medicinal metals function against rheumatoid arthritis and other autoimmune diseases
Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a…
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The ‘widow effect’ is real
In findings that highlight how health effects can reverberate through a social network, a researcher at HMS and his colleague report that the serious illness of an elderly spouse increases…
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DNA copier component found to be real drag
A study in the Feb. 2, 2006 Nature by Antoine van Oijen’s lab sheds light on a longstanding puzzle in DNA replication: how do the enzymes that copy the two…
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Protein underlies brain’s response to activity
Experience helps shape the brain, but how that happens – how synapses are remodeled in response to activity – is one of neurobiology’s biggest mysteries. Though axons and dendrites can…
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Professor shines light on shadowy condition
Sandra Fallman avoided mirrors. Walking down sidewalks during dates, she would avoid bright storefront lights, walking near the curb to stay in the shadows. She put 25-watt bulbs in her apartment lights, not to set the mood, but to provide cover. Fallman suffers from a little-known mental condition called body dysmorphic disorder (BDD).
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Computer use deleted as carpal tunnel syndrome cause
The popular belief that excessive computer use causes painful carpal tunnel syndrome has been contradicted by experts at Harvard Medical School. According to them, even as much as seven hours a day of tapping on a computer keyboard won’t increase your risk of this disabling disorder.
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Meditation found to increase brain size
People who meditate grow bigger brains than those who don’t. Researchers at Harvard, Yale, and the Massachusetts Institute of Technology have found the first evidence that meditation can alter the physical structure of our brains. Brain scans they conducted reveal that experienced meditators boasted increased thickness in parts of the brain that deal with attention and processing sensory input.
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All placebos not created equal
While researchers usually use placebos in clinical trials to test the effectiveness of a new treatment, a trial reported in the Feb. 1, 2006 British Medical Journal pitted one placebo against another.
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Less than half of U.S. health care workers get flu shots
Steffie Woolhandler, Harvard Medical School associate professor of medicine at Cambridge Health Alliance, and colleagues at the University of California Los Angeles analyzed data from the 2000 National Health Interview…
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Long-term memory controlled by molecular pathway at synapses
Even for a fruit fly, learning and memory are important adaptive tools that facilitate survival in the environment. A fly can learn to avoid what may do it harm, such…
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Alternative screening could cut cervical cancer deaths in poor nations
In the right hands, a swab of vinegar and a flashlight may detect more cervical cancer around the world than the recommended cytological screening known as a Pap smear. At the right time, a single DNA test for the virus that causes cervical cancer may also outperform repeated Pap smears.
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Synthetic molecule blocks exit from cell organelle
The ubiquitous, small GTPases are a family of signal transduction molecules that play crucial roles in numerous biological processes, including cell motility and division. Though scientists have eyed these proteins…
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RNAi solution knocks down herpes infection
Ever since RNA interference hit the scene a few years ago as a way to selectively turn off gene expression, researchers have been investigating whether these small but powerful bits…
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Marine biology mystery solved
The narwhal has a tooth, or tusk, which emerges from the left side of the upper jaw and is an evolutionary mystery that defies many of the known principles of…
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Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses – a novel strategy called “metronomic” delivery – achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an…
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Dog genome unleashed
An international research team led by scientists at the Broad Institute of MIT and Harvard has decoded the DNA of the domestic dog and pinpointed millions of genetic differences that…
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Teen suicide and antidepressants
With the recent FDA warning about the use of antidepressants with children and adolescents, doctors and patients are more cautious about treating youth with antidepressants. Parents and doctors are challenged…
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Lab moves genomic testing into the clinic
The earliest symptom of the inherited heart condition hypertrophic cardiomyopathy can be sudden death at a tragically young age. Harvard Medical School researchers discovered the first human gene underlying the…
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Dendritic spines don’t go with the flow
Neurons receive incoming signals through synapses at hundreds of dendritic spines, the lollipop-shaped structures with thin necks and bubblelike heads that stud the surface of dendrites. Each spine serves as…
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Internet discussion group provides an inspiring, supportive ‘oasis’ for people with diabetes, Joslin study shows
A study that appears in the November/December 2005 issue of The Diabetes Educator examined the impact of Joslin’s Online Discussion Boards – forums in which people with diabetes can find…
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Moms who breastfeed may be protected from type 2 diabetes
Researchers have demonstrated that breastfeeding a child for one year may reduce a woman’s risk of developing type 2 diabetes by 15 percent. This study appeared in the Nov. 23,…
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Warning labels on high-risk drugs inconsistently heeded by doctors
In a survey of approximately 930,000 ambulatory care patients, researchers from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care) and colleagues found…
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Brain protein may play role in innate and learned fear
In a paper published in the November 2005 issue of Cell, researchers reported that the protein stathmin is essential for the fear response – both the expression of innate fear…
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International multi-center study confirms value of blood test to diagnose heart failure
Congestive heart failure, which occurs when an impaired heart muscle cannot pump blood efficiently, is a growing health problem and major cause of cardiac death. The diagnosis of heart failure…
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Kids too often prescribed antibiotics for sore throat
Each year, millions of children visit their family physician or pediatrician seeking treatment for sore throats. While a sore throat could indicate many common illnesses, physicians are often most concerned…
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Bacterium present in eyes with ‘wet’ age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in Americans over the age of 55. The majority of vision loss is due to neovascular AMD, the advanced form…
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Study: No psychological or cognitive deficits from peyote
Researchers at Harvard-affiliated McLean Hospital report that Native Americans who use the hallucinogen peyote regularly in connection with religious ceremonies show no evidence of brain damage or psychological problems. In…
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New findings help explain how brain pathways control body weight
A study led by a scientific team at Beth Israel Deaconess Medical Center provides another important step in our understanding of the critical role that the brain’s molecular pathways play…