{"id":171508,"date":"2015-06-08T14:43:50","date_gmt":"2015-06-08T18:43:50","guid":{"rendered":"http:\/\/webadmin.news-harvard.go-vip.net\/gazette\/gazette\/?p=171508"},"modified":"2015-06-08T14:43:50","modified_gmt":"2015-06-08T18:43:50","slug":"injectable-electronics-promise-sharper-view-of-brain","status":"publish","type":"post","link":"https:\/\/news.harvard.edu\/gazette\/story\/2015\/06\/injectable-electronics-promise-sharper-view-of-brain\/","title":{"rendered":"Injectable device delivers nano-view of the brain"},"content":{"rendered":"\n\t\n\t
\n\t\t\t\n\t\t\tScience & Tech\t\t<\/a>\n\t\t\n\t\t

\n\t\tInjectable device delivers nano-view of the brain\t<\/h1>\n\n\t\n\t\n\t
\n\t\t
\n\t\t\t
\n\t\t\t\t\t

\n\t\tPeter Reuell\t<\/p>\n\t\t\t

\n\t\t\tHarvard Staff Writer\t\t<\/p>\n\t\t\t\t\t<\/address>\n\t\t<\/div>\n\n\t\t

\n\t\t\tPromise against disease in electronic scaffolds \t\t<\/h2>\n\t\t\n<\/header>\n\n\n\n
\n\n\n\t\t

It\u2019s a notion that might have come from the pages of a science-fiction novel \u2014 an electronic device that can be injected directly into the brain, or other body parts, and treat everything from neurodegenerative disorders to paralysis.<\/p>\n

Sounds unlikely, until you visit Charles Lieber\u2019s lab.<\/p>\n

Led by Lieber, the Mark Hyman Jr. Professor of Chemistry, an international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons. The research is described in a June 8 paper in Nature Nanotechnology.<\/p>\n

Contributors to the work include Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, and Ying Fang.<\/p>\n

\u201cI do feel that this has the potential to be revolutionary,\u201d said Lieber, who holds a joint appointment in the Harvard Paulson School of Engineering and Applied Sciences. \u201cThis opens up a completely new frontier where we can explore the interface between electronic structures and biology. For the past 30 years, people have made incremental improvements in micro-fabrication techniques that have allowed us to make rigid probes smaller and smaller, but no one has addressed this issue \u2014 the electronics\/cellular interface \u2014 at the level at which biology works.\u201d<\/p>\n

In an earlier study, scientists in Lieber\u2019s lab demonstrated that cardiac or nerve cells grown with embedded scaffolds could be used to create \u201ccyborg\u201d tissue. Researchers were then able to record electrical signals generated by the tissue, and to measure changes in those signals as they administered cardio- or neuro-stimulating drugs.<\/p>\n

\u201cWe were able to demonstrate that we could make this scaffold and culture cells within it, but we didn\u2019t really have an idea how to insert that into pre-existing tissue,\u201d Lieber said. \u201cBut if you want to study the brain or develop the tools to explore the brain-machine interface, you need to stick something into the body. When releasing the electronic scaffold completely from the fabrication substrate, we noticed that it was almost invisible and very flexible, like a polymer, and could literally be sucked into a glass needle or pipette. From there, we simply asked, \u2018Would it be possible to deliver the mesh electronics by syringe needle injection?\u2019\u201d<\/p>\n

Though not the first attempt at implanting electronics into the brain \u2014 deep brain stimulation has been used to treat a variety of disorders for decades \u2014 the nanofabricated scaffolds operate on a completely different scale.<\/p>\n

\u201cExisting techniques are crude relative to the way the brain is wired,\u201d Lieber said. \u201cWhether it\u2019s a silicon probe or flexible polymers \u2026 they cause inflammation in the tissue that requires periodically changing the position or the stimulation.<\/p>\n

\u201cBut with our injectable electronics, it\u2019s as if it\u2019s not there at all. They are one million times more flexible than any state-of-the-art flexible electronics and have subcellular feature sizes. They\u2019re what I call \u2018neuro-philic\u2019 \u2014 they actually like to interact with neurons.\u201d<\/p>\n

The process for fabricating the scaffolds is similar to that used to etch microchips, and begins with a dissolvable layer deposited on a substrate. To create the scaffold, researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is then dissolved, leaving the flexible mesh, which can be drawn into a needle and administered like any other injection.<\/p>\n

The input-output of the mesh can then be connected to standard measurement electronics so that the integrated devices can be addressed and used to stimulate or record neural activity.<\/p>\n

\u201cThese type of things have never been done before, from both a fundamental neuroscience and medical perspective,\u201d Lieber said. \u201cIt\u2019s really exciting \u2014 there are a lot of potential applications.\u201d<\/p>\n

Going forward, researchers hope to better understand how the body reacts to the injectable electronics over longer periods.<\/p>\n

Harvard\u2019s Office of Technology Development<\/a> has filed for a provisional patent on the technology and is actively seeking commercialization opportunities.<\/p>\n

\u201cThe idea of being able to precisely position and record from very specific areas, or even from specific neurons over an extended period of time \u2014 this could, I think, make a huge impact on neuroscience,\u201d Lieber said.<\/p>\n\n\n\n<\/div>\n\n\t\t","protected":false},"excerpt":{"rendered":"

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class=\"article-header__meta\">\n\t\t<div class=\"wp-block-post-author\">\n\t\t\t<address class=\"wp-block-post-author__content\">\n\t\t\t\t\t<p class=\"author wp-block-post-author__name\">\n\t\tPeter Reuell\t<\/p>\n\t\t\t<p class=\"wp-block-post-author__byline\">\n\t\t\tHarvard Staff Writer\t\t<\/p>\n\t\t\t\t\t<\/address>\n\t\t<\/div>\n\n\t\t<time class=\"article-header__date\" datetime=\"2015-06-08\">\n\t\t\tJune 8, 2015\t\t<\/time>\n\n\t\t<span class=\"article-header__reading-time\">\n\t\t\t4 min read\t\t<\/span>\n\t<\/div>\n\n\t\t\t<\/div>\n\t\t\n\t\t\t<h2 class=\"article-header__subheading wp-block-heading\">\n\t\t\tPromise against disease in electronic scaffolds \t\t<\/h2>\n\t\t\n<\/header>\n"},"2":{"blockName":"core\/group","attrs":{"templateLock":false,"metadata":{"name":"Article content"},"align":"wide","layout":{"type":"constrained","justifyContent":"center"},"tagName":"div","lock":[],"className":"","style":[],"backgroundColor":"","textColor":"","gradient":"","fontSize":"","fontFamily":"","borderColor":"","ariaLabel":"","anchor":""},"innerBlocks":[{"blockName":"core\/freeform","attrs":{"content":"","lock":[],"metadata":[]},"innerBlocks":[],"innerHTML":"\n\t\t<p>It\u2019s a notion that might have come from the pages of a science-fiction novel \u2014 an electronic device that can be injected directly into the brain, or other body parts, and treat everything from neurodegenerative disorders to paralysis.<\/p>\n<p>Sounds unlikely, until you visit Charles Lieber\u2019s lab.<\/p>\n<p>Led by Lieber, the Mark Hyman Jr. Professor of Chemistry, an international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons. The research is described in a June 8 paper in Nature Nanotechnology.<\/p>\n<p>Contributors to the work include Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, and Ying Fang.<\/p>\n<p>\u201cI do feel that this has the potential to be revolutionary,\u201d said Lieber, who holds a joint appointment in the Harvard Paulson School of Engineering and Applied Sciences. \u201cThis opens up a completely new frontier where we can explore the interface between electronic structures and biology. For the past 30 years, people have made incremental improvements in micro-fabrication techniques that have allowed us to make rigid probes smaller and smaller, but no one has addressed this issue \u2014 the electronics\/cellular interface \u2014 at the level at which biology works.\u201d<\/p>\n<p>In an earlier study, scientists in Lieber\u2019s lab demonstrated that cardiac or nerve cells grown with embedded scaffolds could be used to create \u201ccyborg\u201d tissue. Researchers were then able to record electrical signals generated by the tissue, and to measure changes in those signals as they administered cardio- or neuro-stimulating drugs.<\/p>\n<p>\u201cWe were able to demonstrate that we could make this scaffold and culture cells within it, but we didn\u2019t really have an idea how to insert that into pre-existing tissue,\u201d Lieber said. \u201cBut if you want to study the brain or develop the tools to explore the brain-machine interface, you need to stick something into the body. When releasing the electronic scaffold completely from the fabrication substrate, we noticed that it was almost invisible and very flexible, like a polymer, and could literally be sucked into a glass needle or pipette. From there, we simply asked, \u2018Would it be possible to deliver the mesh electronics by syringe needle injection?\u2019\u201d<\/p>\n<p>Though not the first attempt at implanting electronics into the brain \u2014 deep brain stimulation has been used to treat a variety of disorders for decades \u2014 the nanofabricated scaffolds operate on a completely different scale.<\/p>\n<p>\u201cExisting techniques are crude relative to the way the brain is wired,\u201d Lieber said. \u201cWhether it\u2019s a silicon probe or flexible polymers \u2026 they cause inflammation in the tissue that requires periodically changing the position or the stimulation.<\/p>\n<p>\u201cBut with our injectable electronics, it\u2019s as if it\u2019s not there at all. They are one million times more flexible than any state-of-the-art flexible electronics and have subcellular feature sizes. They\u2019re what I call \u2018neuro-philic\u2019 \u2014 they actually like to interact with neurons.\u201d<\/p>\n<p>The process for fabricating the scaffolds is similar to that used to etch microchips, and begins with a dissolvable layer deposited on a substrate. To create the scaffold, researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is then dissolved, leaving the flexible mesh, which can be drawn into a needle and administered like any other injection.<\/p>\n<p>The input-output of the mesh can then be connected to standard measurement electronics so that the integrated devices can be addressed and used to stimulate or record neural activity.<\/p>\n<p>\u201cThese type of things have never been done before, from both a fundamental neuroscience and medical perspective,\u201d Lieber said. \u201cIt\u2019s really exciting \u2014 there are a lot of potential applications.\u201d<\/p>\n<p>Going forward, researchers hope to better understand how the body reacts to the injectable electronics over longer periods.<\/p>\n<p>Harvard\u2019s <a href=\"http:\/\/otd.harvard.edu\/\">Office of Technology Development<\/a> has filed for a provisional patent on the technology and is actively seeking commercialization opportunities.<\/p>\n<p>\u201cThe idea of being able to precisely position and record from very specific areas, or even from specific neurons over an extended period of time \u2014 this could, I think, make a huge impact on neuroscience,\u201d Lieber said.<\/p>\n\n","innerContent":["\n\t\t<p>It\u2019s a notion that might have come from the pages of a science-fiction novel \u2014 an electronic device that can be injected directly into the brain, or other body parts, and treat everything from neurodegenerative disorders to paralysis.<\/p>\n<p>Sounds unlikely, until you visit Charles Lieber\u2019s lab.<\/p>\n<p>Led by Lieber, the Mark Hyman Jr. Professor of Chemistry, an international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons. The research is described in a June 8 paper in Nature Nanotechnology.<\/p>\n<p>Contributors to the work include Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, and Ying Fang.<\/p>\n<p>\u201cI do feel that this has the potential to be revolutionary,\u201d said Lieber, who holds a joint appointment in the Harvard Paulson School of Engineering and Applied Sciences. \u201cThis opens up a completely new frontier where we can explore the interface between electronic structures and biology. For the past 30 years, people have made incremental improvements in micro-fabrication techniques that have allowed us to make rigid probes smaller and smaller, but no one has addressed this issue \u2014 the electronics\/cellular interface \u2014 at the level at which biology works.\u201d<\/p>\n<p>In an earlier study, scientists in Lieber\u2019s lab demonstrated that cardiac or nerve cells grown with embedded scaffolds could be used to create \u201ccyborg\u201d tissue. Researchers were then able to record electrical signals generated by the tissue, and to measure changes in those signals as they administered cardio- or neuro-stimulating drugs.<\/p>\n<p>\u201cWe were able to demonstrate that we could make this scaffold and culture cells within it, but we didn\u2019t really have an idea how to insert that into pre-existing tissue,\u201d Lieber said. \u201cBut if you want to study the brain or develop the tools to explore the brain-machine interface, you need to stick something into the body. When releasing the electronic scaffold completely from the fabrication substrate, we noticed that it was almost invisible and very flexible, like a polymer, and could literally be sucked into a glass needle or pipette. From there, we simply asked, \u2018Would it be possible to deliver the mesh electronics by syringe needle injection?\u2019\u201d<\/p>\n<p>Though not the first attempt at implanting electronics into the brain \u2014 deep brain stimulation has been used to treat a variety of disorders for decades \u2014 the nanofabricated scaffolds operate on a completely different scale.<\/p>\n<p>\u201cExisting techniques are crude relative to the way the brain is wired,\u201d Lieber said. \u201cWhether it\u2019s a silicon probe or flexible polymers \u2026 they cause inflammation in the tissue that requires periodically changing the position or the stimulation.<\/p>\n<p>\u201cBut with our injectable electronics, it\u2019s as if it\u2019s not there at all. They are one million times more flexible than any state-of-the-art flexible electronics and have subcellular feature sizes. They\u2019re what I call \u2018neuro-philic\u2019 \u2014 they actually like to interact with neurons.\u201d<\/p>\n<p>The process for fabricating the scaffolds is similar to that used to etch microchips, and begins with a dissolvable layer deposited on a substrate. To create the scaffold, researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is then dissolved, leaving the flexible mesh, which can be drawn into a needle and administered like any other injection.<\/p>\n<p>The input-output of the mesh can then be connected to standard measurement electronics so that the integrated devices can be addressed and used to stimulate or record neural activity.<\/p>\n<p>\u201cThese type of things have never been done before, from both a fundamental neuroscience and medical perspective,\u201d Lieber said. \u201cIt\u2019s really exciting \u2014 there are a lot of potential applications.\u201d<\/p>\n<p>Going forward, researchers hope to better understand how the body reacts to the injectable electronics over longer periods.<\/p>\n<p>Harvard\u2019s <a href=\"http:\/\/otd.harvard.edu\/\">Office of Technology Development<\/a> has filed for a provisional patent on the technology and is actively seeking commercialization opportunities.<\/p>\n<p>\u201cThe idea of being able to precisely position and record from very specific areas, or even from specific neurons over an extended period of time \u2014 this could, I think, make a huge impact on neuroscience,\u201d Lieber said.<\/p>\n\n"],"rendered":"\n\t\t<p>It\u2019s a notion that might have come from the pages of a science-fiction novel \u2014 an electronic device that can be injected directly into the brain, or other body parts, and treat everything from neurodegenerative disorders to paralysis.<\/p>\n<p>Sounds unlikely, until you visit Charles Lieber\u2019s lab.<\/p>\n<p>Led by Lieber, the Mark Hyman Jr. Professor of Chemistry, an international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons. The research is described in a June 8 paper in Nature Nanotechnology.<\/p>\n<p>Contributors to the work include Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, and Ying Fang.<\/p>\n<p>\u201cI do feel that this has the potential to be revolutionary,\u201d said Lieber, who holds a joint appointment in the Harvard Paulson School of Engineering and Applied Sciences. \u201cThis opens up a completely new frontier where we can explore the interface between electronic structures and biology. For the past 30 years, people have made incremental improvements in micro-fabrication techniques that have allowed us to make rigid probes smaller and smaller, but no one has addressed this issue \u2014 the electronics\/cellular interface \u2014 at the level at which biology works.\u201d<\/p>\n<p>In an earlier study, scientists in Lieber\u2019s lab demonstrated that cardiac or nerve cells grown with embedded scaffolds could be used to create \u201ccyborg\u201d tissue. Researchers were then able to record electrical signals generated by the tissue, and to measure changes in those signals as they administered cardio- or neuro-stimulating drugs.<\/p>\n<p>\u201cWe were able to demonstrate that we could make this scaffold and culture cells within it, but we didn\u2019t really have an idea how to insert that into pre-existing tissue,\u201d Lieber said. \u201cBut if you want to study the brain or develop the tools to explore the brain-machine interface, you need to stick something into the body. When releasing the electronic scaffold completely from the fabrication substrate, we noticed that it was almost invisible and very flexible, like a polymer, and could literally be sucked into a glass needle or pipette. From there, we simply asked, \u2018Would it be possible to deliver the mesh electronics by syringe needle injection?\u2019\u201d<\/p>\n<p>Though not the first attempt at implanting electronics into the brain \u2014 deep brain stimulation has been used to treat a variety of disorders for decades \u2014 the nanofabricated scaffolds operate on a completely different scale.<\/p>\n<p>\u201cExisting techniques are crude relative to the way the brain is wired,\u201d Lieber said. \u201cWhether it\u2019s a silicon probe or flexible polymers \u2026 they cause inflammation in the tissue that requires periodically changing the position or the stimulation.<\/p>\n<p>\u201cBut with our injectable electronics, it\u2019s as if it\u2019s not there at all. They are one million times more flexible than any state-of-the-art flexible electronics and have subcellular feature sizes. They\u2019re what I call \u2018neuro-philic\u2019 \u2014 they actually like to interact with neurons.\u201d<\/p>\n<p>The process for fabricating the scaffolds is similar to that used to etch microchips, and begins with a dissolvable layer deposited on a substrate. To create the scaffold, researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is then dissolved, leaving the flexible mesh, which can be drawn into a needle and administered like any other injection.<\/p>\n<p>The input-output of the mesh can then be connected to standard measurement electronics so that the integrated devices can be addressed and used to stimulate or record neural activity.<\/p>\n<p>\u201cThese type of things have never been done before, from both a fundamental neuroscience and medical perspective,\u201d Lieber said. \u201cIt\u2019s really exciting \u2014 there are a lot of potential applications.\u201d<\/p>\n<p>Going forward, researchers hope to better understand how the body reacts to the injectable electronics over longer periods.<\/p>\n<p>Harvard\u2019s <a href=\"http:\/\/otd.harvard.edu\/\">Office of Technology Development<\/a> has filed for a provisional patent on the technology and is actively seeking commercialization opportunities.<\/p>\n<p>\u201cThe idea of being able to precisely position and record from very specific areas, or even from specific neurons over an extended period of time \u2014 this could, I think, make a huge impact on neuroscience,\u201d Lieber said.<\/p>\n\n"}],"innerHTML":"\n<div class=\"wp-block-group alignwide\">\n\n\n\n<\/div>\n","innerContent":["\n<div class=\"wp-block-group alignwide\">\n\n","\n\n<\/div>\n"],"rendered":"\n<div class=\"wp-block-group alignwide has-global-padding is-content-justification-center is-layout-constrained wp-block-group-is-layout-constrained\">\n\n\n\t\t<p>It\u2019s a notion that might have come from the pages of a science-fiction novel \u2014 an electronic device that can be injected directly into the brain, or other body parts, and treat everything from neurodegenerative disorders to paralysis.<\/p>\n<p>Sounds unlikely, until you visit Charles Lieber\u2019s lab.<\/p>\n<p>Led by Lieber, the Mark Hyman Jr. Professor of Chemistry, an international team of researchers has developed a method of fabricating nanoscale electronic scaffolds that can be injected via syringe. The scaffolds can then be connected to devices and used to monitor neural activity, stimulate tissues, or even promote regeneration of neurons. The research is described in a June 8 paper in Nature Nanotechnology.<\/p>\n<p>Contributors to the work include Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, and Ying Fang.<\/p>\n<p>\u201cI do feel that this has the potential to be revolutionary,\u201d said Lieber, who holds a joint appointment in the Harvard Paulson School of Engineering and Applied Sciences. \u201cThis opens up a completely new frontier where we can explore the interface between electronic structures and biology. For the past 30 years, people have made incremental improvements in micro-fabrication techniques that have allowed us to make rigid probes smaller and smaller, but no one has addressed this issue \u2014 the electronics\/cellular interface \u2014 at the level at which biology works.\u201d<\/p>\n<p>In an earlier study, scientists in Lieber\u2019s lab demonstrated that cardiac or nerve cells grown with embedded scaffolds could be used to create \u201ccyborg\u201d tissue. Researchers were then able to record electrical signals generated by the tissue, and to measure changes in those signals as they administered cardio- or neuro-stimulating drugs.<\/p>\n<p>\u201cWe were able to demonstrate that we could make this scaffold and culture cells within it, but we didn\u2019t really have an idea how to insert that into pre-existing tissue,\u201d Lieber said. \u201cBut if you want to study the brain or develop the tools to explore the brain-machine interface, you need to stick something into the body. When releasing the electronic scaffold completely from the fabrication substrate, we noticed that it was almost invisible and very flexible, like a polymer, and could literally be sucked into a glass needle or pipette. From there, we simply asked, \u2018Would it be possible to deliver the mesh electronics by syringe needle injection?\u2019\u201d<\/p>\n<p>Though not the first attempt at implanting electronics into the brain \u2014 deep brain stimulation has been used to treat a variety of disorders for decades \u2014 the nanofabricated scaffolds operate on a completely different scale.<\/p>\n<p>\u201cExisting techniques are crude relative to the way the brain is wired,\u201d Lieber said. \u201cWhether it\u2019s a silicon probe or flexible polymers \u2026 they cause inflammation in the tissue that requires periodically changing the position or the stimulation.<\/p>\n<p>\u201cBut with our injectable electronics, it\u2019s as if it\u2019s not there at all. They are one million times more flexible than any state-of-the-art flexible electronics and have subcellular feature sizes. They\u2019re what I call \u2018neuro-philic\u2019 \u2014 they actually like to interact with neurons.\u201d<\/p>\n<p>The process for fabricating the scaffolds is similar to that used to etch microchips, and begins with a dissolvable layer deposited on a substrate. To create the scaffold, researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is then dissolved, leaving the flexible mesh, which can be drawn into a needle and administered like any other injection.<\/p>\n<p>The input-output of the mesh can then be connected to standard measurement electronics so that the integrated devices can be addressed and used to stimulate or record neural activity.<\/p>\n<p>\u201cThese type of things have never been done before, from both a fundamental neuroscience and medical perspective,\u201d Lieber said. \u201cIt\u2019s really exciting \u2014 there are a lot of potential applications.\u201d<\/p>\n<p>Going forward, researchers hope to better understand how the body reacts to the injectable electronics over longer periods.<\/p>\n<p>Harvard\u2019s <a href=\"http:\/\/otd.harvard.edu\/\">Office of Technology Development<\/a> has filed for a provisional patent on the technology and is actively seeking commercialization opportunities.<\/p>\n<p>\u201cThe idea of being able to precisely position and record from very specific areas, or even from specific neurons over an extended period of time \u2014 this could, I think, make a huge impact on neuroscience,\u201d Lieber said.<\/p>\n\n\n\n<\/div>\n"}},"jetpack-related-posts":[{"id":185124,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2016\/07\/the-bionic-cardiac-patch\/","url_meta":{"origin":171508,"position":0},"title":"The bionic cardiac patch","author":"harvardgazette","date":"July 7, 2016","format":false,"excerpt":"Harvard Professor Charles Lieber and other scientists conducted a study that describes the construction of nanoscale electronic scaffolds that can be seeded with cardiac cells to produce a bionic cardiac patch.","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/news.harvard.edu\/gazette\/section\/health\/"},"img":{"alt_text":"","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/07\/nanoelectronic605.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/07\/nanoelectronic605.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/07\/nanoelectronic605.jpg?resize=525%2C300 1.5x"},"classes":[]},{"id":286097,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2019\/09\/a-new-paper-examines-how-neuron-like-implants-could-treat-brain-disorders\/","url_meta":{"origin":171508,"position":1},"title":"The future of mind control","author":"Lian Parsons","date":"September 20, 2019","format":false,"excerpt":"A new paper explores why neuron-like implants could offer a better way to treat brain disorders, control prosthetics, or even enhance cognitive abilities.","rel":"","context":"In "Science & Tech"","block_context":{"text":"Science & Tech","link":"https:\/\/news.harvard.edu\/gazette\/section\/science-technology\/"},"img":{"alt_text":"raditional-neural-electrodes-versus-mesh-electronics","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/09\/Traditional-neural-electrodes-versus-mesh-electronics1.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/09\/Traditional-neural-electrodes-versus-mesh-electronics1.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/09\/Traditional-neural-electrodes-versus-mesh-electronics1.jpg?resize=525%2C300 1.5x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/09\/Traditional-neural-electrodes-versus-mesh-electronics1.jpg?resize=700%2C400 2x"},"classes":[]},{"id":228093,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2017\/07\/chemist-charles-m-lieber-receives-harvards-highest-faculty-honor\/","url_meta":{"origin":171508,"position":2},"title":"Charles M. Lieber named University Professor","author":"harvardgazette","date":"July 20, 2017","format":false,"excerpt":"Acclaimed chemist Charles M. Lieber has been named a University Professor and is the first to receive the Joshua and Beth Friedman University Professorship.","rel":"","context":"In "Campus & Community"","block_context":{"text":"Campus & Community","link":"https:\/\/news.harvard.edu\/gazette\/section\/campus-community\/"},"img":{"alt_text":"","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2017\/07\/062817_lieber_1466_605.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2017\/07\/062817_lieber_1466_605.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2017\/07\/062817_lieber_1466_605.jpg?resize=525%2C300 1.5x"},"classes":[]},{"id":267825,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2019\/03\/harvard-neuronlike-brain-implants-may-help-treat-disease-mental-illness\/","url_meta":{"origin":171508,"position":3},"title":"Sensors go undercover to outsmart the brain","author":"Lian Parsons","date":"March 12, 2019","format":false,"excerpt":"Harvard scientists have created brain implants so similar to neurons that they actually encourage tissue regeneration in animal models. They may one day be used to help treat neurological diseases, brain damage, and even mental illness.","rel":"","context":"In "Science & Tech"","block_context":{"text":"Science & Tech","link":"https:\/\/news.harvard.edu\/gazette\/section\/science-technology\/"},"img":{"alt_text":"Charles Lieber.","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/03\/062817_Lieber_14621.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/03\/062817_Lieber_14621.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/03\/062817_Lieber_14621.jpg?resize=525%2C300 1.5x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2019\/03\/062817_Lieber_14621.jpg?resize=700%2C400 2x"},"classes":[]},{"id":116133,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2012\/08\/merging-the-biological-electronic\/","url_meta":{"origin":171508,"position":4},"title":"Merging the biological, electronic","author":"harvardgazette","date":"August 26, 2012","format":false,"excerpt":"For the first time, Harvard scientists have created a type of cyborg tissue by embedding a 3-D network of functional, biocompatible, nanoscale wires into engineered human tissues.","rel":"","context":"In "Science & Tech"","block_context":{"text":"Science & Tech","link":"https:\/\/news.harvard.edu\/gazette\/section\/science-technology\/"},"img":{"alt_text":"","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2012\/08\/112105_lieber_350.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2012\/08\/112105_lieber_350.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2012\/08\/112105_lieber_350.jpg?resize=525%2C300 1.5x"},"classes":[]},{"id":182900,"url":"https:\/\/news.harvard.edu\/gazette\/story\/2016\/04\/advancing-ingenuity\/","url_meta":{"origin":171508,"position":5},"title":"Advancing ingenuity","author":"harvardgazette","date":"April 28, 2016","format":false,"excerpt":"One of the projects receiving support from the accelerator was developed by Charles Lieber, Mark Hyman Jr. Professor of Chemistry, who has invented polymer-like mesh electronics and a method of delivering the electronics by syringe injection into living organisms. Credit: Lieber Research Group Between academic discovery and product development lurks\u2026","rel":"","context":"In "Science & Tech"","block_context":{"text":"Science & Tech","link":"https:\/\/news.harvard.edu\/gazette\/section\/science-technology\/"},"img":{"alt_text":"","src":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/04\/lieber_pressfigure2_605.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/04\/lieber_pressfigure2_605.jpg?resize=350%2C200 1x, https:\/\/news.harvard.edu\/wp-content\/uploads\/2016\/04\/lieber_pressfigure2_605.jpg?resize=525%2C300 1.5x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/posts\/171508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/users\/105622744"}],"replies":[{"embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/comments?post=171508"}],"version-history":[{"count":0,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/posts\/171508\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/media\/171511"}],"wp:attachment":[{"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/media?parent=171508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/categories?post=171508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/tags?post=171508"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/gazette-formats?post=171508"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/news.harvard.edu\/gazette\/wp-json\/wp\/v2\/series?post=171508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}