Tag: Rett syndrome
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Nation & World
Spirit of inquiry
Harvard Medical School’s Benyam Kinde, Ph.D. ’16, M.D., ’18, led investigations that uncovered a novel role of the MECP2 protein — which when mutated leads to the devastating neurodevelopmental disorder Rett syndrome — in regulating gene expression in the developing brain.
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Nation & World
New drug target for Rett syndrome
Rett syndrome is a relatively common neurodevelopmental disorder, the second most common cause of intellectual disability in girls after Down syndrome. Building on 2004 findings, Harvard researchers identified a faulty signaling pathway that, when corrected in mice, improves the symptoms of Rett syndrome.