Tag: fibrosis

  • Nation & World

    The cellular origin of fibrosis

    Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.

    3 minutes
  • Nation & World

    Solving the problem of shape-shifters

    Investigators at Harvard-affiliated Massachusetts General Hospital (MGH) may have found a way to solve a problem that has plagued ligand-mimicking integrin inhibitors, a group of drugs that have the potential to treat conditions ranging from heart attacks to cancer metastasis.

    2 minutes
  • Nation & World

    A cross-country collaboration

    Amy Wagers and Emmanuelle Passegué have found that cancer stem cells actively remodel the environment of bone marrow, where blood cells are formed, so that it is hospitable only to diseased cells. This finding could influence the effectiveness of bone marrow transplants.

    4 minutes