Tag: Genetics
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Nation & World
‘Speed limit’ found on rate of evolution
Harvard University scientists have identified a virtual “speed limit” on the rate of molecular evolution in organisms, and the magic number appears to be six mutations per genome per generation — a rate of change beyond which species run the strong risk of extinction as their genomes lose stability.
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Nation & World
Scientists synthesize memory in yeast cells
Harvard Medical School (HMS) researchers have successfully synthesized a DNA-based memory loop in yeast cells, an experiment that marks a significant step forward in the emerging field of synthetic biology.
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Nation & World
First robust genetic link to height in humans identified
Over a century ago, scientists first proposed that height is a complex trait — one influenced by environmental factors and multiple genes. While subsequent studies revealed that most of the…
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Nation & World
Scientists have something to chew on
In a groundbreaking study, two Harvard scientists have for the first time extracted human DNA from ancient artifacts. The work potentially opens up a new universe of sources for ancient genetic material, which is used to map human migrations in prehistoric times.
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Nation & World
Brain implants relieve Alzheimer’s damage
Genetically engineered cells implanted in mice have cleared away toxic plaques associated with Alzheimer’s disease.
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Nation & World
Gene variants significantly increase risk for breast cancer
Newly identified inherited variants of a single gene increase breast cancer risk for women of European ancestry approximately 20 percent if they carry one copy of the gene and by 60 percent if they carry two copies. These variants, in the FGFR2 (Fibroblast Growth Factor Receptor 2) gene, were found in more than half of…
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Nation & World
Opossum genome shows ‘junk’ DNA source of genetic innovation
A tiny opossum’s genome has shed light on how evolution creates new creatures from old, showing that change primarily comes by finding new ways of turning existing genes on and…
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Nation & World
Advances in genetics can help kids learn
Education was becoming a no-brainer, some people at Harvard’s Graduate School of Education (HGSE) complained. Kurt Fischer and his colleagues looked at the revolution in brain scanning, genetics, and other biological technologies and decided that most teachers and students weren’t getting much benefit from them.
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Nation & World
Manipulating genetic switch in mice eases MD symptoms
Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.
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Nation & World
Genome-wide map will help fight diabetes
The Broad Institute of MIT and Harvard, Lund University, and Novartis have announced the completion of a genome-wide map of genetic differences in humans and their relationship to type 2 diabetes and other metabolic disorders. The announcement was made Monday (Feb. 12). All results of the analysis are being made accessible, free of charge, on…
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Nation & World
Viruses get the silent treatment, any disease is a target
What do you do if you’re sure you’ve found a way to knock out the AIDS virus but you can’t get the medicine into infected cells? That was the problem faced by Judy Lieberman, a professor of pediatrics at Harvard Medical School.
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Nation & World
Mystery muscles make mightier mice
Scientists have muscled in on a genetic switch that allows mice to run longer and faster. Humans possess the same switch, so the discovery might open new paths to treating muscle-wasting diseases and building better bodies.
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Nation & World
World’s largest flower evolved from family of much tinier blooms
The plant with the world’s largest flower – typically a full meter across, with a bud the size of a basketball – evolved from a family of plants whose blossoms are nearly all tiny, botanists write this week in the journal Science. Their genetic analysis of rafflesia reveals that it is closely related to a…
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Nation & World
HSPH, Broad map malaria genetic diversity
Researchers have created the first map of genetic diversity of the malaria parasite, providing new insights in the fight against a public health scourge that kills one person every 30 seconds.
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Nation & World
Research finds mutation that causes Noonan syndrome
Scientists have discovered that mutations in a gene known as SOS1 account for many cases of Noonan syndrome (NS), a common childhood genetic disorder that occurs in one in 1,000…
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Nation & World
Fruit fly bouts show gender-specific styles
Fighting like a girl or fighting like a boy is hardwired into fruit fly neurons, according to a study in the Nov. 19 Nature Neuroscience advance online publication by a…
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Nation & World
Harvard researchers map new form of genetic diversity
A new map of human genetic diversity provides a powerful tool for understanding how each person is unique. Created by researchers at Harvard Medical School, Brigham and Women’s Hospital, and…
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Nation & World
Sensitivity to pain explained
Stabbing back pain or the aches of arthritis send some people to bed in misery while the same distress seems easily tolerated by others.
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Nation & World
Genetic ‘road map’ leads to discoveries
A research team led by scientists at the Broad Institute of MIT and Harvard announced Sept. 28 the development of a new kind of genetic “road map” that can connect…
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Nation & World
HMS’s Szostak wins prestigious Lasker
Jack W. Szostak, professor of genetics at Harvard Medical School, is among this year’s Lasker Award winners. Now celebrating its 61st anniversary, the Lasker Awards are the nation’s most distinguished honor for outstanding contributions to basic and clinical medical research, as well as for special achievement in the medical research enterprise.
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Nation & World
Sons of American Revolution welcome Gates
Henry Louis Gates Jr., W.E.B. Du Bois Professor of the Humanities and director of the W.E.B. Du Bois Institute for African and African American Research at Harvard, was inducted into the Sons of the American Revolution (SAR) on July 10 at the society’s 116th annual convention, held in Addison, Texas.
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Nation & World
HSCI/MGH researchers identify gene product involved in stem cell aging and death
A multi-institutional team of Harvard researchers may have advanced our understanding of physiological aging with a new study in which they greatly reduced the impact of aging on blood stem cells. A report on their findings appears in the latest edition of the journal Nature along with similar but independent findings from research teams at…
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Nation & World
Schepens scientists first to discover angiogenesis switch inside blood vessel cells
Scientists at Schepens Eye Research Institute, an affiliate of Harvard Medical School, are the first to discover a switch inside blood vessel cells that controls angiogenesis (new blood vessel growth).…
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Nation & World
Scientists discover new genetic subtypes of common blood cancer
Scientists at Dana-Farber Cancer Institute and collaborators have identified four distinct genetic subtypes of multiple myeloma, a deadly blood cancer, that have different prognoses and might be treated most effectively…
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Nation & World
X inactivation seen as contact sport
At an early stage in a female embryo’s development, one of the two X chromosomes in each of its cells becomes inactivated. In two recent papers, the lab of Jeannie…
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Nation & World
RNA sequence restrains fatal encephalitis
One short sequence of RNA protected mice from deadly brain inflammation caused by West Nile virus and Japanese encephalitis virus, report Priti Kumar, Manjunath Swamy, and Premlata Shankar. The findings,…
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Nation & World
Binge eating disorder may have genetic ties
Researchers at Harvard-affiliated McLean Hospital have reported that binge eating disorder runs in families, raising the possibility that this condition may have a genetic basis. In the study, published in…
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Nation & World
DNA copier component found to be real drag
A study in the Feb. 2, 2006 Nature by Antoine van Oijen’s lab sheds light on a longstanding puzzle in DNA replication: how do the enzymes that copy the two…
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Nation & World
Brigham pilot program connects people with family histories
A Harvard Medical School instructor at Brigham and Women’s Hospital is spearheading a pilot project to encourage Brigham employees to gather detailed family health histories to give health care officials an edge fighting inherited diseases.